scholarly journals Patient-Reported Side Effects of Intradetrusor Botulinum Toxin Type A for Idiopathic Overactive Bladder Syndrome

2011 ◽  
Vol 86 (1) ◽  
pp. 68-72 ◽  
Author(s):  
Ricarda M. Bauer ◽  
Christian Gratzke ◽  
Alexander Roosen ◽  
Yasmin Hocaoglu ◽  
Margit E. Mayer ◽  
...  
2021 ◽  
pp. 205141582110166
Author(s):  
Timothy P Napier-Hemy ◽  
Oladapo Feyisetan ◽  
Heather Stewart ◽  
Alaa Chamsin ◽  
Michael S Floyd ◽  
...  

Objectives: To determine whether administration of single dose prophylactic intravenous gentamicin prior to intravesical injection of botulinum toxin type A (BoNT-A) is associated with adverse extravesical neuromuscular effects in idiopathic overactive bladder syndrome. Patients and methods: A retrospective analysis of 220 consecutive idiopathic overactive bladder patients following sedation-free flexible cystoscopic injection of intravesical BoNT-A. All patients received a single dose of intravenous gentamicin (160 mg) followed by 100-200 IU of BoNT-A. They were followed up at intervals to determine whether they had experienced any adverse extravesical neuromuscular side effects. Results: None of our patients developed adverse extravesical neuromuscular side effects from intravesical botulinum injections with concomitant administration of intravenous gentamicin. Conclusion: Single dose intravenous gentamicin is safe to use as a prophylaxis for intravesical BoNT-A injections of 200 IU or below in idiopathic overactive bladder patients. Level of evidence: Not applicable.


2014 ◽  
Vol 47 (4) ◽  
pp. 528-532 ◽  
Author(s):  
José Abraão Carneiro Neto ◽  
Valéria Gusmão Bittencourt ◽  
Cassius de Oliveira ◽  
Rosana Andrade ◽  
Edgar Marcelino de Carvalho

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