scholarly journals Enhancement of the Frequency and Function of IL-10-Secreting Type I T Regulatory Cells after 1 Year of Cluster Allergen-Specific Immunotherapy

2012 ◽  
Vol 159 (4) ◽  
pp. 391-398 ◽  
Author(s):  
Wei Lou ◽  
Chengshuo Wang ◽  
Yang Wang ◽  
Demin Han ◽  
Luo Zhang
Keyword(s):  
Specific Immunotherapy ◽  
T Regulatory Cells ◽  
Type I ◽  
Regulatory Cells ◽  
Allergen Specific Immunotherapy ◽  
And Function

scholarly journals Allergen-specific immunotherapy: an update on immunological mechanisms of action

2016 ◽  
Vol 65 (1) ◽  
Author(s):  
G. Ciprandi ◽  
G.L. Marseglia ◽  
M.A. Tosca
Keyword(s):  
Specific Immunotherapy ◽  
T Regulatory Cells ◽  
Sublingual Immunotherapy ◽  
Mechanisms Of Action ◽  
Regulatory Cells ◽  
Allergen Specific Immunotherapy ◽  
Specific Antibodies ◽  
Immunological Mechanisms ◽  
Specific Igg4 ◽  
History Of

Specific immunotherapy (SIT) is the only treatment able to modify the natural history of the allergic subjects. Several aspects of the immunopathological response modified by SIT have been investigated; the first parameter historically studied was the production of allergen-specific antibodies. An increase of allergen-specific IgG4 and a decrease of IgE appear after SIT. A shift from Th2-polarized immune response toward Th1-oriented pattern has been reported after SIT. More recently, a crucial role for a subpopulation of T cells has been evidenced: T regulatory cells (Treg). Allergic patients have a defect of Tregs. SIT is able of inducing a specific Treg response. Sublingual immunotherapy is an alternative route of administration for SIT. Recent evidence shows that SLIT is also able of inducing a Treg response as detected by IL- 10 production.

Mechanisms of Allergen-Specific Immunotherapy: T-Regulatory Cells and More

2006 ◽  
Vol 26 (2) ◽  
pp. 207-231 ◽  
Author(s):  
Johan Verhagen ◽  
Kurt Blaser ◽  
Cezmi A. Akdis ◽  
Mübeccel Akdis
Keyword(s):  
Specific Immunotherapy ◽  
T Regulatory Cells ◽  
Regulatory Cells ◽  
Allergen Specific Immunotherapy

T Regulatory Cells in Allergen-Specific Immunotherapy

2005 ◽  
Vol 24 (5-6) ◽  
pp. 533-548 ◽  
Author(s):  
Johan Verhagen ◽  
Alison Taylor ◽  
Kurt Blaser ◽  
Mübeccel Akdis ◽  
Cezmi A. Akdis
Keyword(s):  
Specific Immunotherapy ◽  
T Regulatory Cells ◽  
Regulatory Cells ◽  
Allergen Specific Immunotherapy

scholarly journals CD18 Is Required for Optimal Development and Function of CD4+CD25+ T Regulatory Cells

2005 ◽  
Vol 175 (12) ◽  
pp. 7889-7897 ◽  
Author(s):  
Marissa Marski ◽  
Sravanthi Kandula ◽  
Jerrold R. Turner ◽  
Clara Abraham
Keyword(s):  
T Regulatory Cells ◽  
Regulatory Cells ◽  
Optimal Development ◽  
And Function

Dexamethasone affects day/night development and function of thymus-derived T regulatory cells

Immunobiology ◽  
2019 ◽  
Vol 224 (5) ◽  
pp. 614-624
Author(s):  
Ewelina Kiernozek ◽  
Anna Bieńkowska ◽  
Magdalena Markowska ◽  
Ewa Kozlowska ◽  
Nadzieja Drela
Keyword(s):  
T Regulatory Cells ◽  
Regulatory Cells ◽  
And Function

scholarly journals Pertussis toxin as an adjuvant suppresses the number and function of CD4+CD25+ T regulatory cells

2006 ◽  
Vol 36 (3) ◽  
pp. 671-680 ◽  
Author(s):  
Xin Chen ◽  
Robin T. Winkler-Pickett ◽  
Nicholas H. Carbonetti ◽  
John R. Ortaldo ◽  
Joost J. Oppenheim ◽  
...  
Keyword(s):  
Pertussis Toxin ◽  
T Regulatory Cells ◽  
Regulatory Cells ◽  
And Function

Regulatory cells in allergen-specific immunotherapy

Immunotherapy ◽  
2012 ◽  
Vol 4 (4) ◽  
pp. 389-396 ◽  
Author(s):  
Michael B Soyka ◽  
David Holzmann ◽  
Cezmi A Akdis
Keyword(s):  
Specific Immunotherapy ◽  
Regulatory Cells ◽  
Allergen Specific Immunotherapy

scholarly journals Runx1 and Runx3 Are Involved in the Generation and Function of Highly Suppressive IL-17-Producing T Regulatory Cells

PLoS ONE ◽  
2012 ◽  
Vol 7 (9) ◽  
pp. e45115 ◽  
Author(s):  
Lequn Li ◽  
Nikolaos Patsoukis ◽  
Victoria Petkova ◽  
Vassiliki A. Boussiotis
Keyword(s):  
T Regulatory Cells ◽  
Regulatory Cells ◽  
And Function

The anti-cancer agents lenalidomide and pomalidomide inhibit the proliferation and function of T regulatory cells

2008 ◽  
Vol 58 (7) ◽  
pp. 1033-1045 ◽  
Author(s):  
Christine Galustian ◽  
Brendan Meyer ◽  
Marie-Christine Labarthe ◽  
Keith Dredge ◽  
Deborah Klaschka ◽  
...  
Keyword(s):  
T Regulatory Cells ◽  
Regulatory Cells ◽  
Anti Cancer ◽  
And Function
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