The Influence of Tumor Growth Kinetics on the Response to Radiation Therapy and Drug Therapy in Man

Author(s):  
Edmond P. Malaise ◽  
Nicole Chavaudra ◽  
Marcelle Guichard ◽  
Adel Courdi ◽  
Tabar� V�zquez

2004 ◽  
Vol 64 (3) ◽  
pp. 1094-1101 ◽  
Author(s):  
Monica Simeoni ◽  
Paolo Magni ◽  
Cristiano Cammia ◽  
Giuseppe De Nicolao ◽  
Valter Croci ◽  
...  


2015 ◽  
Vol 40 (8) ◽  
pp. 3043-3051 ◽  
Author(s):  
Adeel R. Seyal ◽  
Keyur Parekh ◽  
Atilla Arslanoglu ◽  
Fernanda D. Gonzalez-Guindalini ◽  
Sandra M. Tochetto ◽  
...  


BMC Cancer ◽  
2010 ◽  
Vol 10 (1) ◽  
Author(s):  
Luis E Bergues Cabrales ◽  
Juan J Godina Nava ◽  
Andrés Ramírez Aguilera ◽  
Javier A González Joa ◽  
Héctor M Camué Ciria ◽  
...  


2009 ◽  
Vol 16 (10) ◽  
pp. 2834-2839 ◽  
Author(s):  
Jonathan H. Lee ◽  
Seza A. Gulec ◽  
Ainura Kyshtoobayeva ◽  
Myung-Shin Sim ◽  
Donald L. Morton


Oncotarget ◽  
2020 ◽  
Vol 11 (18) ◽  
pp. 1618-1628
Author(s):  
Andy Karabajakian ◽  
Thibaut Garrivier ◽  
Carole Crozes ◽  
Nicolas Gadot ◽  
Jean-Yves Blay ◽  
...  


2014 ◽  
Vol 21 (8) ◽  
pp. 950-957 ◽  
Author(s):  
Adeel R. Seyal ◽  
Keyur Parekh ◽  
Yuri S. Velichko ◽  
Riad Salem ◽  
Vahid Yaghmai


1988 ◽  
Vol 74 (3) ◽  
pp. 269-274 ◽  
Author(s):  
Romano Demicheli ◽  
Roberto Foroni ◽  
Fernando C. Giuliani ◽  
Giuseppina Savi

The influence of tumor growth kinetics on response to doxorubicin treatment of C3H mammary carcinoma was investigated. Gompertzian growth curves were obtained for the tumor mass of each mouse by a computerized best fit program. The response was assessed by evaluating: a) the total clonogenic cell reduction as a fraction of the initial tumor volume or the tumor volume that should result at the end of treatment in a free growth condition, and b) the partial clonogenic cell reduction at each drug administration, assuming a first order cell kill hypothesis. Slowly growing tumors at each dose level showed a significantly poorer response than rapidly growing tumors. Each response index exhibited a linear correlation with the specific instantaneous growth rate at the time of treatment. Data also suggested a dose-response dependence.



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