Regulatory Effect of Neurotransmitter by Hemofiltration in Cardiogenic Shock Patients after Open Heart Surgery

Author(s):  
F. I. Coraim ◽  
Alyson Owen ◽  
W. Trubel ◽  
H. Kassal ◽  
K. Widhalm

1976 ◽  
Vol 10 (3) ◽  
pp. 231-235 ◽  
Author(s):  
Morten Kveim ◽  
Chr. Cappelen ◽  
Tor Frøysaker ◽  
Karl Victor Hall


2020 ◽  
Vol 4 (1) ◽  
pp. 1-6 ◽  
Author(s):  
Michael DiVita ◽  
Gautam K Visveswaran ◽  
Kasaiah Makam ◽  
Peyman Naji ◽  
Marc Cohen ◽  
...  

Abstract Background  Acute severe mitral regurgitation (MR) associated with cardiogenic shock is a life-threatening emergency. Traditional teaching has focused on the need for emergent coronary angiography and/or intra-aortic balloon counterpulsation in preparation for emergent open-heart surgery for repair/replacement. Unfortunately, emergent open-heart surgery in patients with acute MR complicated by cardiogenic shock is associated with 25–46% perioperative mortality. New devices have provided additional options for stabilization prior to emergent surgery which facilitate improved outcomes. Case summary  We present two cases of acute severe MR resulting in cardiogenic shock and profound hypoxaemia. TandemHeart® mechanical circulatory support with an oxygenator spliced into the circuit, akin to veno-arterial extracorporeal membrane oxygenation (ECMO), facilitated haemodynamic stabilization and decongestion of the lungs facilitating successful bridge to mitral valve surgery. Successful discharge to home was achieved in both patients with good neurological outcomes and sustained long-term functional recovery at 18 and 14 months, respectively. Discussion Selective use of the TandemHeart®, with or without ECMO, facilitates management of the critically ill cardiogenic shock patient with acute severe MR.



CHEST Journal ◽  
1988 ◽  
Vol 94 (3) ◽  
pp. 503-506 ◽  
Author(s):  
Kevin H. Olsen ◽  
Jeffrey Kluger ◽  
Arnold Fieldman


1978 ◽  
Vol 39 (02) ◽  
pp. 474-487 ◽  
Author(s):  
E R Cole ◽  
F Bachmann ◽  
C A Curry ◽  
D Roby

SummaryA prospective study in 13 patients undergoing open-heart surgery with extracorporeal circulation revealed a marked decrease of the mean one-stage prothrombin time activity from 88% to 54% (p <0.005) but lesser decreases of factors I, II, V, VII and X. This apparent discrepancy was due to the appearance of an inhibitor of the extrinsic coagulation system, termed PEC (Protein after Extracorporeal Circulation). The mean plasma PEC level rose from 0.05 U/ml pre-surgery to 0.65 U/ml post-surgery (p <0.0005), and was accompanied by the appearance of additional proteins as evidenced by disc polyacrylamide gel electrophoresis of plasma fractions (p <0.0005). The observed increases of PEC, appearance of abnormal protein bands and concomitant increases of LDH and SGOT suggest that the release of an inhibitor of the coagulation system (similar or identical to PIVKA) may be due to hypoxic liver damage during extracorporeal circulation.



1967 ◽  
Vol 18 (03/04) ◽  
pp. 634-646 ◽  
Author(s):  
N Thurnherr

SummaryBlood clotting investigations have been executed in 25 patients who have undergone open heart surgery with extracorporeal circulation. A description of alterations in the activity of blood clotting factors, the fibrinolytic system, prothrombin consumption and platelets during several phases of the operation is given.



2005 ◽  
Vol 53 (S 3) ◽  
Author(s):  
U Boeken ◽  
P Feindt ◽  
J Litmathe ◽  
E Gams




2007 ◽  
Vol 55 (S 1) ◽  
Author(s):  
N Madershahian ◽  
T Wittwer ◽  
J Strauch ◽  
J Wippermann ◽  
UFW Franke ◽  
...  


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