Ruthenium-106 Eye Plaque Brachytherapy in the Conservative Treatment of Uveal Melanoma: Evaluation of 175 Patients Treated with 150 Gy from 1981�1989

Author(s):  
R. P�tter ◽  
K. Janssen ◽  
F. J. Prott ◽  
J. Widder ◽  
U. Haverkamp ◽  
...  

Brachytherapy ◽  
2017 ◽  
Vol 16 (6) ◽  
pp. 1225-1231 ◽  
Author(s):  
Alexander J. Lin ◽  
Yuan J. Rao ◽  
Sahaja Acharya ◽  
Julie Schwarz ◽  
Prabakar Kumar Rao ◽  
...  


2011 ◽  
Vol 99 ◽  
pp. S354
Author(s):  
K. Leonard ◽  
N. Gagne ◽  
J. Mignano ◽  
J. Duker ◽  
E. Bannon ◽  
...  


2015 ◽  
Vol 93 (3) ◽  
pp. E77-E78
Author(s):  
P. Jiang ◽  
G. Kanzia ◽  
D. Neumann ◽  
J. Roider ◽  
J. Dunst


2014 ◽  
Vol 4 (4) ◽  
pp. e189-e194 ◽  
Author(s):  
Vinita Takiar ◽  
Dan S. Gombos ◽  
Firas Mourtada ◽  
Laura A. Rechner ◽  
Ann A. Lawyer ◽  
...  


2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Ping Jiang ◽  
Konstantine Purtskhvanidze ◽  
Gerit Kandzia ◽  
Dirk Neumann ◽  
Ulf Luetzen ◽  
...  


Author(s):  
A.J. Lin ◽  
Y.J. Rao ◽  
S. Acharya ◽  
J.K. Schwarz ◽  
P.K. Rao ◽  
...  


2021 ◽  
pp. 100712
Author(s):  
Neil Chevli ◽  
Amy C. Schefler ◽  
Maria E. Bretana ◽  
Ramiro Pino ◽  
E. Brian Butler ◽  
...  


Brachytherapy ◽  
2011 ◽  
Vol 10 (4) ◽  
pp. 331-339 ◽  
Author(s):  
Kara L. Leonard ◽  
Nolan L. Gagne ◽  
John E. Mignano ◽  
Jay S. Duker ◽  
Elizabeth A. Bannon ◽  
...  


Author(s):  
K.L. Leonard ◽  
E.A. Bannon ◽  
J.E. Mignano ◽  
J.S. Duker ◽  
N. Gagne ◽  
...  


2020 ◽  
Author(s):  
Ping Jiang ◽  
Konstantine Purtskhvanidze ◽  
Gerit Kandzia ◽  
Dirk Neumann ◽  
Ulf Luetzen ◽  
...  

Abstract Background: To evaluate 106Ruthenium Brachytherapy in management of medium sized uveal melanoma, with emphasis on 5-year outcome and toxicity.Methods: From 2007 to 2015, 39 patients were treated with 106 Ru eye plaques brachytherapy. At the time of diagnosis, the median tumor depth was 3.0 mm (CI: 1.6-8.9 mm). Median dose at the apex of the tumor was 145 Gy (± SD: 12.1Gy). The median sclera dose was 444.0Gy (±SD: 257.3 Gy). Results: Median follow-up was 61.5 months (CI: 8.1-138 mon.). 34 patients (87.1%) remained free of recurrence. In 26 (66.7%) patients a total regression was achieved after a median period of 12 months (CI: 3-60 mon.). By the final examination, the visual acuity of 26 (66.7%) patients was better than 20/200. 12 (30.7%) patients had a visual acuity better than 20/40.Retinopathy was detected in 11 (28.2%) patients. After treatments only 1 (5.1%) patients had active vascular changes by the last examination. Moderate optic neuropathy was observed in 4 (10.3%) patients. Cataract development was diagnosed in 21 (53.8%) patients, although 16 (41%) of them had bilateral cataract development.Special emphasis was made on patients with larger tumors. Twelve out of the 39 patients had a tumor with a depth of 5mm or more. There was no significant difference neither in local control (75 % in tumors ≥5mm versus 92.6 % in tumors <5mm) nor in side effects between both groups. Conclusions: Our study proved 106 Ru -brachytherapy to be an excellent treatment option with regard to tumor control and preservation of the visual acuity in well-selected patients. The data suggest that this treatment is also suitable for tumors with a depth of more than 5mm.



Sign in / Sign up

Export Citation Format

Share Document