A Possible Role for Helicobacter pylori in the Pathogenesis of Reflux Esophagitis

2015 ◽  
pp. 9-19
Author(s):  
Peter Malfertheiner ◽  
Gianpiero Manes ◽  
Andreas Hackelsberger ◽  
Joachim Labenz ◽  
J. Enrique Dominguez-Mu�oz
Keyword(s):  
Helicobacter Pylori ◽  
Reflux Esophagitis

Reflux Esophagitis and Helicobacter Pylori Infection in Patients with Systemic Scleroderma

2006 ◽  
Vol 63 (5) ◽  
pp. AB138
Author(s):  
Kanako Yamaguchi ◽  
Ryuichi Iwakiri ◽  
Akiko Danjyo ◽  
Yasuhisa Sakata ◽  
Hibiki Ootani ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Reflux Esophagitis ◽  
Helicobacter Pylori Infection ◽  
Systemic Scleroderma

50 - Reflux Esophagitis after Helicobacter Pylori Eradication: The Role of Gastric Acid Secretion

2018 ◽  
Vol 154 (6) ◽  
pp. S-17
Author(s):  
Francesco Di Mario ◽  
Serena Scida ◽  
Marilisa Franceschi ◽  
Chiara Miraglia ◽  
Kryssia Rodriguez ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Acid Secretion ◽  
Gastric Acid Secretion ◽  
Gastric Acid ◽  
Reflux Esophagitis ◽  
Helicobacter Pylori Eradication

scholarly journals Incidence of reflux esophagitis and Helicobacter pylori infection in diabetic patients

2008 ◽  
Vol 14 (20) ◽  
pp. 3212 ◽  
Author(s):  
Ken Ariizumi ◽  
Tomoyuki Koike ◽  
Shuichi Ohara ◽  
Yoshifumi Inomata ◽  
Yasuhiko Abe ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Reflux Esophagitis ◽  
Helicobacter Pylori Infection ◽  
Diabetic Patients

Helicobacter Pylori Infection Inhibits Reflux Esophagitis by Inducing Atrophic Gastritis

1999 ◽  
Vol 94 (12) ◽  
pp. 3468-3472 ◽  
Author(s):  
Tomoyuki Koike ◽  
Shuichi Ohara ◽  
Hitoshi Sekine ◽  
Katsunori Iijima ◽  
Katsuaki Kato ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Atrophic Gastritis ◽  
Reflux Esophagitis ◽  
Helicobacter Pylori Infection

Efficacy of Helicobacter pylori eradication therapy for reflux esophagitis

2001 ◽  
Vol 120 (5) ◽  
pp. A432
Author(s):  
Kazuki Ohta ◽  
Hiroto Miwa ◽  
Ryuichi Ohkura ◽  
Akihito Nagahara ◽  
Toshio Murai ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Reflux Esophagitis ◽  
Eradication Therapy ◽  
Helicobacter Pylori Eradication ◽  
Helicobacter Pylori Eradication Therapy

scholarly journals Effect of Helicobacter pylori Eradication on Reflux Esophagitis Therapy

2015 ◽  
Vol 128 (8) ◽  
pp. 995-999 ◽  
Author(s):  
Yan Xue ◽  
Li-Ya Zhou ◽  
San-Ren Lin ◽  
Xiao-Hua Hou ◽  
Zhao-Shen Li ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Reflux Esophagitis ◽  
Helicobacter Pylori Eradication

scholarly journals Verrucous antral gastritis in relation to Helicobacter pylori infection, nutrition, and gastric atrophy

2019 ◽  
Vol 8 (4) ◽  
pp. 293-298
Author(s):  
Naoko Tsuji ◽  
Yasuko Umehara ◽  
Mamoru Takenaka ◽  
Yasunori Minami ◽  
Tomohiro Watanabe ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Reflux Esophagitis ◽  
English Literature ◽  
Indigo Carmine ◽  
Gastric Atrophy ◽  
Helicobacter Pylori Infection ◽  
Antral Gastritis ◽  
Numerous Type ◽  
History Of ◽  
H Pylori

Abstract Background There have been few studies in the English literature regarding verrucous gastritis (VG). The present study investigated the clinical and endoscopic features of verrucous antral gastritis, especially focusing on Helicobacter pylori infection, nutrition, and gastric atrophy. Methods We performed a retrospective study of patients who underwent routine endoscopy with indigo carmine chromoendoscopy and a comparative study was conducted between VG-positive and VG-negative groups. VG was subdivided into classical and numerous types based on the number and distribution of verrucous lesions. Demographic, clinical, and endoscopic data including body mass index (BMI), serum albumin and cholesterol, gastric atrophy, reflux oesophagitis, Barrett’s oesophagus, and H. pylori status were collected. Univariate and multivariable analyses were performed to identify factors associated with VG. Results We analysed the data of 621 patients undergoing routine endoscopy and found that VG (n = 352) was significantly associated with increased BMI (1.12 [1.05–1.18], P < 0.01), reflux esophagitis (1.96 [1.10–3.28], P < 0.01), and H. pylori negativity with or without a history of eradication (9.94 [6.00–16.47] and 6.12 [3.51–10.68], P < 0.001, respectively). Numerous-type (n = 163) VG was associated with both closed- and open-type gastric atrophy (9.9 [4.04–21.37] and 8.10 [3.41–19.24], P < 0.001, respectively). There were no statistical differences between groups regarding age, sex, total cholesterol, albumin, and bile-colored gastric juice. Conclusions Verrucous antral gastritis was related to increased BMI, reflux esophagitis, and H. pylori negativity. Numerous-type verrucous lesions were associated with gastric atrophy. These indicate that VG may be a physiological phenomenon due to high gastric acidity, mechanical overload, and vulnerability of background mucosa.

scholarly journals Endoscopic Reflux Esophagitis and Reflux-Related Symptoms after Helicobacter pylori Eradication Therapy: Meta-Analysis

2020 ◽  
Vol 9 (9) ◽  
pp. 3007 ◽  
Author(s):  
Mitsushige Sugimoto ◽  
Masaki Murata ◽  
Hitomi Mizuno ◽  
Eri Iwata ◽  
Naoyoshi Nagata ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Reflux Esophagitis ◽  
Reflux Disease ◽  
Meta Analysis ◽  
Eradication Therapy ◽  
Case Group ◽  
Inclusion Criteria ◽  
Helicobacter Pylori Eradication ◽  
Significant Difference ◽  
H Pylori

Backgrounds: The etiology of gastroesophageal reflux disease (GERD) including reflux esophagitis and non-erosive reflux disease is multifactorial and a recent meta-analysis showed no association between the development of GERD and Helicobacter pylori eradication in both Western and East-Asian populations. However, the problem remains that various inclusion criteria are used in these studies, which hinders meta-analysis. With a focus on reflux esophagitis with endoscopic mucosal injury, we meta-analysed to evaluate the association between eradication and reflux esophagitis and symptoms using a clearly defined set of inclusion criteria. Methods: We conducted a meta-analysis of studies published up until March 2020, which compared the incidence of reflux esophagitis and symptoms between patients undergoing H. pylori eradication therapy in a randomized placebo-controlled trial (Category A); between patients with successful and failed eradication (Category B); and between patients with successful vs. failed eradication, receipt of placebo, or no-treatment H. pylori-positives (Category C). Results: A total of 27 studies were included. Significant statistical effects were found for development of endoscopic reflux esophagitis [relative risk (RR): 1.46, 95% confidence interval (CI): 1.16–1.84, p = 0.01] or de novo reflux esophagitis (RR: 1.42, 95% CI: 1.01–2.00, p = 0.03) in the case group that received eradication in all studies, especially in Western populations. There was no significant difference in the incidence of symptoms after eradication between patient and control groups, regardless of category, location of population, or baseline disease. Conclusions: Eradication therapy for H pylori increases the risk of reflux esophagitis, irrespective of past history of esophagitis. In contrast, no effect was seen on reflux-related symptoms.

IL1B and IL1RN polymorphic genes and Helicobacter pylori cagA strains decrease the risk of reflux esophagitis

2004 ◽  
Vol 127 (1) ◽  
pp. 73-79 ◽  
Author(s):  
Dulciene Maria Magalhães Queiroz ◽  
Juliana Becattini Guerra ◽  
Gifone Aguiar Rocha ◽  
Andreia Maria Camargos Rocha ◽  
Adriana Santos ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Reflux Esophagitis ◽  
Polymorphic Genes
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