scholarly journals Remarkable Improvement of Nail Changes in Alopecia Areata Universalis with 10 Months of Treatment with Tofacitinib: A Case Report

2016 ◽  
Vol 8 (3) ◽  
pp. 262-266 ◽  
Author(s):  
Sineida Berbert Ferreira ◽  
Morton Scheinberg ◽  
Denise Steiner ◽  
Tatiana Steiner ◽  
Gustavo Longhi Bedin ◽  
...  
Keyword(s):  
Case Report ◽  
Alopecia Areata ◽  
Whole Body ◽  
Nail Dystrophy ◽  
Main Symptom ◽  
Remarkable Improvement ◽  
Nail Changes ◽  
Function Recovery ◽  
Patient Consent ◽  
Chronic Autoimmune Disease

Alopecia areata (AA) is a chronic, autoimmune disease. The main symptom is massive hair loss, localized or diffuse, in the scalp and the whole body. However, nails may also be involved, and brittleness, fragility and pitting can be signs of nail dystrophy in AA patients. Here, we report the case of a male patient with AA refractory to various treatments, including oral, topical and intralesional corticosteroids, immunosuppressants, cyclosporin and PUVA (oxoralen plus ultraviolet light), all interrupted due to side effects. The patient’s nails had erythematous blotches (striated lunulae) with regular and superficial pitting as well as fragility (trachyonychia), and he could no longer play the guitar because of these symptoms. With patient consent, we introduced tofacitinib (5 mg twice daily), which resulted in remarkable improvements not only regarding hair regrowth but also nail changes, with function recovery within 10 months.

A Single Nail Dystrophy as a Unique Manifestation of Sarcoidosis: A Case Report

2021 ◽  
pp. 1-4
Author(s):  
Laura Mengeot ◽  
Bernard Stallenberg ◽  
Ivan Théate ◽  
Oliver Vanhooteghem
Keyword(s):  
Case Report ◽  
Clinical Evaluation ◽  
Systemic Disease ◽  
Radiological Examination ◽  
Bone Involvement ◽  
Nail Dystrophy ◽  
Nail Changes ◽  
Osseous Involvement ◽  
Nail Involvement

Sarcoidosis with nail involvement is rare and most commonly affecting plural digits. Nail changes are frequently an indication of systemic disease and underlying bone involvement, thus complete clinical evaluation with bone and thorax radiological examination is a necessity in suspected cases. We report a case of onychodystrophy with osseous involvement of only one finger as unique manifestation of sarcoidosis, which is very rare.

NAIL DYSTROPHY IN PSORIATIC ARTHRITIS PRESENTING AS NAIL ONYCHOMYCOSIS: A CASE REPORT

Hand Surgery ◽  
2012 ◽  
Vol 17 (01) ◽  
pp. 139-142 ◽  
Author(s):  
Joon Yub Kim ◽  
Goo Hyun Baek ◽  
Hyun Sik Gong
Keyword(s):  
Case Report ◽  
Psoriatic Arthritis ◽  
Skin Lesion ◽  
Joint Infection ◽  
Interphalangeal Joint ◽  
Nail Dystrophy ◽  
Rare Form ◽  
Nail Changes ◽  
Methotrexate Treatment ◽  
Dystrophic Nail

Dystrophic nail changes without a skin lesion is a rare form of psoriasis. We describe a patient that presented with a chronic nail onychomycosis and a destructive thumb interphalangeal joint which was initially considered as onychomycotic joint infection, and was later diagnosed as having dystrophic nail changes in psoriatic arthritis and coexistent onychomycosis. The nail changes were completely normalized after methotrexate treatment.

scholarly journals Neuropathic pain post-COVID-19: a case report

2021 ◽  
Vol 14 (7) ◽  
pp. e243459
Author(s):  
Matthew McWilliam ◽  
Michael Samuel ◽  
Fadi Hasan Alkufri
Keyword(s):  
Neuropathic Pain ◽  
Case Report ◽  
Hospital Admission ◽  
Skin Biopsy ◽  
Neurological Examination ◽  
Autonomic Failure ◽  
Whole Body ◽  
Shortness Of Breath ◽  
Burning Pain ◽  
Electrophysiological Tests

A 61-year-old man with no significant medical history developed fever, headache and mild shortness of breath. He tested positive for SARS-CoV-2 and self-isolated at home, not requiring hospital admission. One week after testing positive, he developed acute severe burning pain affecting his whole body, subsequently localised distally in the limbs. There was no ataxia or autonomic failure. Neurological examination was unremarkable. Electrophysiological tests were unremarkable. Skin biopsy, lumbar puncture, enhanced MRI of the brachial plexus and MRI of the neuroaxis were normal. His pain was inadequately controlled with pregabalin but improved while on a weaning regimen of steroids. This case highlights the variety of possible symptoms associated with SARS-CoV-2 infection.

scholarly journals Traumatic myositis ossificans: multifocal lesions suggesting malignancy on FDG-PET/CT—a case report

2020 ◽  
Vol 50 (1) ◽  
pp. 249-254
Author(s):  
Miho Sasaki ◽  
Yuka Hotokezaka ◽  
Reiko Ideguchi ◽  
Masataka Uetani ◽  
Shuichi Fujita
Keyword(s):  
Case Report ◽  
Fdg Pet ◽  
Myositis Ossificans ◽  
Whole Body ◽  
Left Cheek ◽  
Multiple Fractures ◽  
Fdg Uptake ◽  
Pet Ct ◽  
Multiple Regions ◽  
Fdg Pet Ct

AbstractMyositis ossificans (MO) is a benign soft-tissue lesion characterized by the heterotopic formation of the bone in skeletal muscles, usually due to trauma. MO is occasionally difficult to diagnose because of its clinical and radiological similarities with malignancy. We report a case of traumatic MO (TMO) in the masseter and brachial muscles of a 37-year-old man who presented with painless swelling in the left cheek and severe trismus. Due to the absence of a traumatic history at the first consultation and identification of a tumorous lesion in the left masseter muscle by magnetic resonance imaging (MRI), the lesion was suspected to be a malignant tumor. Subsequently, 18F-fluorodeoxyglucose positron-emission tomography/computed tomography (FDG-PET/CT) showed multiple regions of high FDG uptake across the whole body, suggestive of multiple metastases or other systemic diseases. However, intramuscular calcifications were also observed in the left masseter and brachial muscles, overlapping the areas with high FDG uptake. Moreover, multiple fractures were seen in the rib and lumbar spine, also overlapping the areas with high FDG uptake. Based on these imaging findings, along with a history of jet-ski trauma, TMO was suspected. The left cheek mass was surgically excised and histologically diagnosed as TMO. In this case report, FDG-PET/CT could detect multiple TMOs across the whole body. To the best of our knowledge, cases of multiple TMOs located far apart in different muscles are rare, and this may be the first report.

Ayurvedic management of Alopecia areata (Indralupta) with surgical procedure Kuttanam and internal medications: A case report

2021 ◽  
Vol 4 (3) ◽  
pp. 105
Author(s):  
GN Sree Deepthi ◽  
CB Roopesh Kumar ◽  
VKrishna Kumar ◽  
EmyS Surendran ◽  
D Sudhakar ◽  
...  
Keyword(s):  
Case Report ◽  
Alopecia Areata ◽  
Surgical Procedure

Abstract 1122‐000205: Bilateral ACA Stroke ‐ A Case Report of an Unusual Presentation

2021 ◽  
Vol 1 (S1) ◽  
Author(s):  
Tejeswi Suryadevara ◽  
Bhavya Narapureddy ◽  
Carlos Y Lopez ◽  
Karen C Albright
Keyword(s):  
Case Report ◽  
Brain Magnetic Resonance Imaging ◽  
Whole Body ◽  
Rapid Improvement ◽  
Stroke Registry ◽  
Disconnection Syndrome ◽  
Leg Weakness ◽  
Anatomic Variants ◽  
Computed Tomography Angiogram ◽  
Cerebrovascular Risk

Introduction : Bilateral ACA strokes are rare, with one stroke registry reporting 2 cases out of 1490 strokes (1). These strokes are even less common in the absence of anatomic variants, such as an azygos ACA. Diagnosis may be difficult given the variability in clinical presentation. Methods : This is a case report. Results : A 51‐year‐old right handed man with no cerebrovascular risk factors on no antithrombotic medications presented two hours from last known well with complaints of generalized weakness, inability to speak or move, and feeling numb all‐over during intercourse. He reported rapid improvement in symptoms. Emergency room exam was notable for right leg weakness (3/5) and left leg plegia with intact sensation. Hoover’s sign was positive in the left leg and the patient was able to bear some weight while standing with a two‐person assist. A computed tomography angiogram (CTA) of his head and neck was preliminarily interpreted as normal. No azygos ACA or single internal carotid artery origin for the ACAs were present. His exam improved to an isolated left foot dorsiflexor and plantar flexor weakness. The decision was made not to use thrombolytics based on his symptoms and exam which were improving and not entirely consistent with acute stroke. Brain magnetic resonance imaging demonstrated bilateral parasagittal acute strokes. It was later noted the that non‐contrast head CT demonstrated bilateral hyperdense ACAs. Conclusions : This case demonstrates the difficulty in diagnosing bilateral ACA infarcts in a previously healthy adult in the setting of whole‐body numbness and positive Hoover’s sign. In retrospect, his transient inability to speak or move may have been transient akinetic mutism or callosal disconnection syndrome. Additionally, this case emphasizes the importance of evaluating for the hyperdense ACA sign (2) in patients complaining of bilateral leg weakness.

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