A Single Nail Dystrophy as a Unique Manifestation of Sarcoidosis: A Case Report

2021 ◽  
pp. 1-4
Author(s):  
Laura Mengeot ◽  
Bernard Stallenberg ◽  
Ivan Théate ◽  
Oliver Vanhooteghem
Keyword(s):  
Case Report ◽  
Clinical Evaluation ◽  
Systemic Disease ◽  
Radiological Examination ◽  
Bone Involvement ◽  
Nail Dystrophy ◽  
Nail Changes ◽  
Osseous Involvement ◽  
Nail Involvement

Sarcoidosis with nail involvement is rare and most commonly affecting plural digits. Nail changes are frequently an indication of systemic disease and underlying bone involvement, thus complete clinical evaluation with bone and thorax radiological examination is a necessity in suspected cases. We report a case of onychodystrophy with osseous involvement of only one finger as unique manifestation of sarcoidosis, which is very rare.

Psoriatic Nails: A Prospective Clinical Study

2003 ◽  
Vol 7 (4) ◽  
pp. 317-321 ◽  
Author(s):  
Joanna Salomon ◽  
Jacek C. Szepietowski ◽  
Alina Proniewicz
Keyword(s):  
Clinical Study ◽  
Skin Disorder ◽  
Fungal Infections ◽  
Prospective Clinical Study ◽  
Common Symptom ◽  
Clinical Parameters ◽  
Nail Dystrophy ◽  
Predisposing Factor ◽  
Nail Changes ◽  
Nail Involvement

Background: Psoriasis is a widespread skin disorder in which nail involvement is a common symptom. Many psoriatic patients have nail changes morphologically resembling onychomycosis. Objective: The present study was undertaken (1) to evaluate the frequency of nail involvement in psoriatic patients, (2) to assess the types of nail changes in psoriasis, (3) to find eventual relationships between nail involvement and some clinical parameters, and finally (4) to determine the prevalence of fungal nail infections in psoriatic individuals. Material and Methods: One hundred six patients hospitalized in our department due to exacerbation of psoriasis participated in the study. Each patient underwent dermatologic examination with special attention paid to the nail changes. In any case of abnormalities clinically suspected of fungal infection, further mycological investigations were performed. Results: Nail changes were present in 83 patients (78.3%) with psoriasis. The most common nail abnormality observed on both fingernails and toenails was subungual hyperkeratosis. Hyperkeratosis, onychorrexis, and discoloration of nail plates were observed significantly more often on toenails. Pitting and longitudinal ridges were significantly more frequent on fingernails. Patients with psoriatic nail dystrophy were significantly older than psoriatic patients without nail abnormalities. Nails were involved statistically more often in patients with arthropathic psoriasis. Positive mycological cultures were obtained from 18% of patients with nail changes. The most commonly isolated fungi were molds. Conclusions: Dystrophic nails are frequently found in psoriatic individuals, especially those suffering from arthropathic psoriasis. Subungual hyperkeratosis and pitting are the most typical lesions. It is difficult to assess definitively whether psoriasis is a predisposing factor to the development of fungal infections of the nails.

NAIL DYSTROPHY IN PSORIATIC ARTHRITIS PRESENTING AS NAIL ONYCHOMYCOSIS: A CASE REPORT

Hand Surgery ◽  
2012 ◽  
Vol 17 (01) ◽  
pp. 139-142 ◽  
Author(s):  
Joon Yub Kim ◽  
Goo Hyun Baek ◽  
Hyun Sik Gong
Keyword(s):  
Case Report ◽  
Psoriatic Arthritis ◽  
Skin Lesion ◽  
Joint Infection ◽  
Interphalangeal Joint ◽  
Nail Dystrophy ◽  
Rare Form ◽  
Nail Changes ◽  
Methotrexate Treatment ◽  
Dystrophic Nail

Dystrophic nail changes without a skin lesion is a rare form of psoriasis. We describe a patient that presented with a chronic nail onychomycosis and a destructive thumb interphalangeal joint which was initially considered as onychomycotic joint infection, and was later diagnosed as having dystrophic nail changes in psoriatic arthritis and coexistent onychomycosis. The nail changes were completely normalized after methotrexate treatment.

scholarly journals Remarkable Improvement of Nail Changes in Alopecia Areata Universalis with 10 Months of Treatment with Tofacitinib: A Case Report

2016 ◽  
Vol 8 (3) ◽  
pp. 262-266 ◽  
Author(s):  
Sineida Berbert Ferreira ◽  
Morton Scheinberg ◽  
Denise Steiner ◽  
Tatiana Steiner ◽  
Gustavo Longhi Bedin ◽  
...  
Keyword(s):  
Case Report ◽  
Alopecia Areata ◽  
Whole Body ◽  
Nail Dystrophy ◽  
Main Symptom ◽  
Remarkable Improvement ◽  
Nail Changes ◽  
Function Recovery ◽  
Patient Consent ◽  
Chronic Autoimmune Disease

Alopecia areata (AA) is a chronic, autoimmune disease. The main symptom is massive hair loss, localized or diffuse, in the scalp and the whole body. However, nails may also be involved, and brittleness, fragility and pitting can be signs of nail dystrophy in AA patients. Here, we report the case of a male patient with AA refractory to various treatments, including oral, topical and intralesional corticosteroids, immunosuppressants, cyclosporin and PUVA (oxoralen plus ultraviolet light), all interrupted due to side effects. The patient’s nails had erythematous blotches (striated lunulae) with regular and superficial pitting as well as fragility (trachyonychia), and he could no longer play the guitar because of these symptoms. With patient consent, we introduced tofacitinib (5 mg twice daily), which resulted in remarkable improvements not only regarding hair regrowth but also nail changes, with function recovery within 10 months.

scholarly journals Oral and Dental Changes of Dyskeratosis Congenita: A Case Report with Literature Review

2018 ◽  
Vol 9 (1-2) ◽  
pp. 20-23 ◽  
Author(s):  
Gozde Serindere
Keyword(s):  
Case Report ◽  
Early Diagnosis ◽  
Literature Review ◽  
Aggressive Periodontitis ◽  
Dyskeratosis Congenita ◽  
Tooth Decay ◽  
Nail Dystrophy ◽  
Uncommon Disease ◽  
Missing Tooth ◽  
Enamel Layer

Dyskeratosis congenita (DC) is an uncommon disease characterized by nail dystrophy, cutaneous hyperpigmentation, leukoplakia, pancytopenia, and malignant transformation. There can be some oral and dental changes such as oral leukoplakia, increase in tooth decay, hypodontia, thinning of enamel layer, aggressive periodontitis, intraoral brown pigmentation, missing tooth, taurodontism, and blunted roots. Most of cases belong to dermatology or pediatrics department. There are few reports about dentistry. The aim of this report is to lay emphasis on this fatal syndrome among dentists about the multisystem findings and oro-dental changes. Thus, this information may aid dentists in early diagnosis. A case of 21-year-old male diagnosed with DC is reported.

scholarly journals Cardiac Sarcoidosis as an Uncommon Etiology for Posterior Circulation Stroke Presenting with Alexia without Agraphia

2018 ◽  
Vol 2018 ◽  
pp. 1-3
Author(s):  
Mohankumar Kurukumbi ◽  
Lauren Gardiner ◽  
Shevani Sahai ◽  
John W. Cochran
Keyword(s):  
Case Report ◽  
Early Diagnosis ◽  
Cardiac Involvement ◽  
Clinical Presentation ◽  
Cardiac Sarcoidosis ◽  
Systemic Disease ◽  
Pulmonary Sarcoidosis ◽  
Posterior Circulation ◽  
Presenting Symptoms ◽  
Memory And Recall

Sarcoidosis is a systemic disease with cardiac involvement occurring in 20-50% of cases. Cardiogenic stroke caused by cardiac sarcoidosis, especially PCA infarction, is a rare clinical presentation that necessitates timely diagnosis and may warrant treatment prophylaxis against CVA. In this case report, we describe a 54-year-old Caucasian male presenting with left PCA stroke in the setting of cardiac and pulmonary sarcoidosis, and hypertension. His presenting symptoms included right partial hemianopia, difficulty with naming, memory, and recall, and alexia without agraphia. Cardiogenic stroke is an uncommon manifestation of cardiac sarcoidosis, and given the disabling nature of these sequelae, the importance of early diagnosis and prevention with anticoagulation is crucial to prevent morbidity and mortality.

scholarly journals Torsion of the Ovary in Infancy, a Rare Emergency; A Case Report

2021 ◽  
pp. 90-96
Author(s):  
Abdelilah Radi ◽  
Karima Larbi Ouassou ◽  
Amal Hassani ◽  
Rachid Abilkassem ◽  
Aomar Agadr ◽  
...  
Keyword(s):  
Abdominal Pain ◽  
Case Report ◽  
Clinical Evaluation ◽  
Clinical Picture ◽  
Acute Abdominal Pain ◽  
Rare Condition ◽  
Ovarian Torsion ◽  
Positive Diagnosis ◽  
Hemorrhagic Risk ◽  
Made In

Torsion of the ovary is a rare condition whose diagnosis remains difficult given the non-specificity of the clinical picture as well as the difficulty of clinical evaluation, especially in young girls. It is a surgical emergency because it involves the vital prognosis by the hemorrhagic risk, and functional prognosis by the risk of infertility. The clinical picture is dominated by acute abdominal pain. Our work reports the case of a 2-year-old girl in whom the diagnosis of ovarian torsion was made in front of an atypical clinical picture. Laparoscopy is the method of choice for making a positive diagnosis and performing a conservative procedure as described in this work.

scholarly journals Riedel’s thyroiditis as a part of the IgG4 systemic disease: A case report

2021 ◽  
Vol 12 ◽  
pp. 1
Author(s):  
Thamyres Marques ◽  
Bárbara Gehrke ◽  
Francinne Machado Ribeiro ◽  
Marise Machado ◽  
Sérgio de Oliveira Romano ◽  
...  
Keyword(s):  
Case Report ◽  
Systemic Disease ◽  
Riedel’S Thyroiditis ◽  
Riedel's Thyroiditis

scholarly journals Pleural effusion caused by polyostotic fibrous dysplasia involving the ribs, the sternum and the thoracic spine associated with multiple cystic degenerations – a case report

2019 ◽  
Vol 72 (1-2) ◽  
pp. 39-42
Author(s):  
Ivan Ergelasev ◽  
Ivan Kuhajda ◽  
Dejan Djuric ◽  
Danijela Kuhajda ◽  
Sinisa Maksimovic
Keyword(s):  
Case Report ◽  
Pleural Effusion ◽  
Fibrous Dysplasia ◽  
The Body ◽  
Bone Involvement ◽  
Cystic Degeneration ◽  
Histopathological Analysis ◽  
Daily Routine ◽  
Polyostotic Fibrous Dysplasia ◽  
Chest Wall Injury

Introduction. Fibrous dysplasia is a noninherited benign skeletal disorder associated with abnormal bone development. Single bone involvement, the monostotic form, accounts for 70 ? 80% of cases, while the polyostotic form, with multiple bone involvement, accounts for 20 ? 30% of cases. Cystic degeneration and occasional aneurysmal bone cyst formation may be found in fibrous dysplasia lesions, particularly in the costal lesions. Case Report. A 51-year-old man presented with acute shortness of breath after sustaining simple chest wall injury. Chest computed tomography showed multiple massive osteolytic rib lesions, as well as a massive left-sided pleural effusion with compression atelectasis of the lung parenchyma. Osteolytic lesions of the anterior 2nd and 7th thoracic vertebral body were found, along with a well defined osteolytic lesion in the body of the sternum. Video-assisted thoracoscopy of the left pleural space was performed and frozen sections, collected using endoscopic biopsy forceps of the cystic wall and solid parts of the tumors, were sent for ex tempore histopathological analysis. Results showed fibrous dysplasia with suspected malignancy. Talc pleurodesis was performed based on the obtained results. At present, the patient is asymptomatic with his daily routine uninterrupted by his medical condition. Conclusion. Treatment of pleural effusion caused by a cyst rupture of unresectable degenerated polyostotic fibrous dysplasia of the ribs represents a surgical challenge. Surgical drainage of the cysts followed by chemical pleurodesis seems to be a reasonable solution in cases where pulmonary functions are impacted by combined effects of pleural effusion and cystic compression.

Sign in / Sign up

Export Citation Format

Share Document