Correlation of High-Resolution Manometric Findings with Symptoms of Dysphagia and Endoscopic Features in Adults with Eosinophilic Esophagitis

2017 ◽  
Vol 35 (5) ◽  
pp. 472-477 ◽  
Author(s):  
Ulrike von Arnim ◽  
Arne Kandulski ◽  
Jochen Weigt ◽  
Peter Malfertheiner
Keyword(s):  
High Resolution ◽  
Proton Pump ◽  
Eosinophilic Esophagitis ◽  
Esophageal Motility ◽  
Clinical Impact ◽  
Endoscopic Appearance ◽  
High Resolution Manometry ◽  
Chicago Classification ◽  
Significant Difference ◽  
Endoscopic Score

Background: Eosinophilic esophagitis (EoE) presents with dysphagia, but data about motility patterns using high-resolution manometry (HRM) are rare. We aimed at evaluating esophageal motility patterns in EoE and their correlation to endoscopic and dysphagia scores. Methods: Twenty-six EoE patients and 23 controls were included after 4 weeks of treatment with proton pump inhibitors. Dysphagia and endoscopic scores were evaluated before performing HRM. EoE patients were classified to have fibrostenotic (FS) or inflammatory (IF) type. HRM analysis was performed according to the Chicago classification (CC) system. Results: According to the CC, the HRM findings in EoE and controls were normal in 11 (42%) and 20 (88.5%), p < 0.0001. Weak and failed peristaltic integrity was only seen in EoE patients (failed 1/2.7%, weak 7/26.9%, p = 0.004). Of the EoE patients, 17 had IF and 9 presented with FS type. HRM parameters showed no differences according to the EoE subtype. The endoscopic score in the FS subtype was significantly higher than in EoE with IF subtype (5.33 vs. 3.58, p = 0.001). No significant difference was seen in dysphagia scores in EoE subtypes. Discussion: HRM findings in EoE are often diagnostic, but they are non-specific and do not correlate with the severity of dysphagia or endoscopic appearance. The clinical impact of HRM in EoE needs further evaluation.

scholarly journals ESOPHAGEAL MOTILITY IN MEN AND WOMEN EVALUATED BY HIGH-RESOLUTION MANOMETRY

2017 ◽  
Vol 54 (2) ◽  
pp. 145-147 ◽  
Author(s):  
Tarciana Vieira COSTA ◽  
Roberto Oliveira DANTAS
Keyword(s):  
High Resolution ◽  
Esophageal Motility ◽  
Esophageal Manometry ◽  
Sitting Position ◽  
Men And Women ◽  
Proximal Contraction ◽  
High Resolution Manometry ◽  
Contraction Duration ◽  
Significant Difference ◽  
Esophageal Sphincter

ABSTRACT BACKGROUND Esophageal motility has been described in the literature as having differences between men and women. Most of these investigations use the water perfusion method for esophageal manometry. In this investigation the esophageal motility of men and women was compared with high-resolution manometry of the esophagus. OBJECTIVE To compare the esophageal motility of men and women with the high-resolution manometry method for esophageal manometry, performed in the sitting position. The hypothesis was that men and women have differences in esophageal motility. METHODS High-resolution manometry was performed in normal volunteers, 10 men [mean age: 37.5 (8.1) years] and 12 women [mean age: 38.7 (7.5) years], in the sitting position and with 10 swallows of a 5 mL bolus of saline, with an interval of at least 30 seconds between consecutive swallows. We evaluated the integrated relaxation pressure of the lower esophageal sphincter, contraction front velocity, distal contraction integral, distal latency, proximal contraction extension, proximal contraction duration >30 mmHg, proximal contraction duration, proximal contraction integral and maximal upper esophageal sphincter pressure. RESULTS There was no significant difference between men and women in the variables measured. CONCLUSION There was no difference in esophageal motility of men and women evaluated by the high resolution manometry method, in the sitting position with swallows of a liquid bolus.

Clinical impact of different cut-off values in high-resolution manometry systems on diagnosing esophageal motility disorders

2019 ◽  
Vol 54 (12) ◽  
pp. 1078-1082 ◽  
Author(s):  
Shiko Kuribayashi ◽  
Katsuhiko Iwakiri ◽  
Tomohiro Shinozaki ◽  
Hiroko Hosaka ◽  
Akiyo Kawada ◽  
...  
Keyword(s):  
High Resolution ◽  
Esophageal Motility ◽  
Clinical Impact ◽  
Esophageal Motility Disorders ◽  
Motility Disorders ◽  
High Resolution Manometry

scholarly journals Esophageal motility disorders on high‐resolution manometry: Chicago classification version 4.0 ©

2020 ◽  
Vol 33 (1) ◽  
Author(s):  
Rena Yadlapati ◽  
Peter J. Kahrilas ◽  
Mark R. Fox ◽  
Albert J. Bredenoord ◽  
C. Prakash Gyawali ◽  
...  
Keyword(s):  
High Resolution ◽  
Esophageal Motility ◽  
Esophageal Motility Disorders ◽  
Motility Disorders ◽  
High Resolution Manometry ◽  
Chicago Classification

scholarly journals A pictorial presentation of 3.0 Chicago Classification for esophageal motility disorders

2016 ◽  
Vol 14 (3) ◽  
pp. 439-442 ◽  
Author(s):  
Fernando Augusto Herbella ◽  
Priscila Rodrigues Armijo ◽  
Marco Giuseppe Patti
Keyword(s):  
High Resolution ◽  
Esophageal Motility ◽  
Esophagogastric Junction ◽  
Esophageal Motility Disorders ◽  
Motility Disorders ◽  
High Resolution Manometry ◽  
Ineffective Esophageal Motility ◽  
Chicago Classification ◽  
Esophageal Spasm ◽  
Pictorial Presentation

ABSTRACT High resolution manometry changed several esophageal motility paradigms. The 3.0 Chicago Classification defined manometric criteria for named esophageal motility disorders. We present a pictorial atlas of motility disorders. Achalasia types, esophagogastric junction obstruction, absent contractility, distal esophageal spasm, hypercontractile esophagus (jackhammer), ineffective esophageal motility, and fragmented peristalsis are depicted with high-resolution manometry plots.

scholarly journals A PICTORIAL PRESENTATION OF ESOPHAGEAL HIGH RESOLUTION MANOMETRY CURRENT PARAMETERS

2017 ◽  
Vol 30 (1) ◽  
pp. 69-71 ◽  
Author(s):  
Fernanda M. LAFRAIA ◽  
Fernando A. M. HERBELLA ◽  
Julia R. KALLUF ◽  
Marco G. PATTI
Keyword(s):  
High Resolution ◽  
Lower Esophageal Sphincter ◽  
Esophageal Motility ◽  
Clinical Applications ◽  
High Resolution Manometry ◽  
Chicago Classification ◽  
Pictorial Presentation ◽  
New Concepts ◽  
Esophageal Sphincter ◽  
Integrated Relaxation Pressure

ABSTRACT Introduction: High resolution manometry is the current technology used to the study of esophageal motility and is replacing conventional manometry in important centers for esophageal motility with parameters used on esophageal motility, following the Chicago Classification. This classification unifies high resolution manometry interpretation and classifies esophageal disorders. Objective: This review shows, in a pictorial presentation, the new parameters established by the Chicago Classification, version 3.0, aimed to allow an easy comprehension and interpretation of high resolution manometry. Methods: Esophageal manometries performed by the authors were reviewed to select illustrative tracings representing Chicago Classification parameters. Results: The parameters are: Esophagogastric Morphology, that classifies this junction according to its physiology and anatomy; Integrated Relaxation Pressure, that measures the lower esophageal sphincter relaxation; Distal Contractile Integral, that evaluates the contraction vigor of each wave; and, Distal Latency, that measures the peristalsis velocity from the beginning of the swallow to the epiphrenic ampulla. Conclusion: Clinical applications of these new concepts is still under evaluation.

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