scholarly journals The Effect of a Decrease in Intraocular Pressure on Optic Nerve Function in Patients with Optic Nerve Drusen

2017 ◽  
Vol 61 (3) ◽  
pp. 153-158 ◽  
Author(s):  
Dorota Pojda-Wilczek ◽  
Patrycja Wycisło-Gawron
Eye ◽  
2000 ◽  
Vol 14 (3) ◽  
pp. 476-487 ◽  
Author(s):  
George L Spaeth ◽  
Mary Lucy Marques Pereira

2007 ◽  
Vol 10 (s1) ◽  
pp. 101-107 ◽  
Author(s):  
Sinisa D. Grozdanic ◽  
Milan Matic ◽  
Daniel M. Betts ◽  
Donald S. Sakaguchi ◽  
Randy H. Kardon

2018 ◽  
Vol 59 (8) ◽  
pp. 3488 ◽  
Author(s):  
Naoki Kiyota ◽  
Yukihiro Shiga ◽  
Kohei Ichinohasama ◽  
Masayuki Yasuda ◽  
Naoko Aizawa ◽  
...  

2009 ◽  
Vol 137 (3-4) ◽  
pp. 130-133
Author(s):  
Ivan Stefanovic ◽  
Ivan Marjanovic ◽  
Gordana Vlajkovic

Introduction. The ultrasound diagnostics of the optic nerve includes the analysis of the optic nerve disc (PNO) and measuring of its retrobulbar diameter. With B-scan, by Schraeder's method, it is possible to measure very precisely the optic nerve, the pial diameter, the normal values for the pial diameter being 2.8-4.1 mm. In glaucoma, the disease that is most frequently associated with higher intraocular pressure, there comes the destruction of nerve fibres, which can be visualized as the excavation of the optic nerve disc. Objective. In this paper, we were interested in finding whether in glaucoma, and in what phase of the disease, the optic nerve starts growing thinner. Aware of many forms of this very complex disease, we were interested in knowing if the visualization of excavation on the optic nerve disc is related to diminishing of the pial diameter of the retrobulbar nerve part. Methods. There were treated the patients who had already had the diagnosis of glaucoma and the visualized excavation of the optic disc of various dimensions. Echographically, there was measured the thickness of the retrobulbar part of the optic nerve and the finding compared in relation to the excavation of the optic disc. Results. In all eyes with glaucoma, a normal size of the retrobulbar part of the optic nerve was measured, ranging from 3.01 to 3.91 mm with the median of 3.36 mm. Also, by testing the correlation between the thickness of the optic nerve and the excavation of the PNO, by Pearson test, we found that there was no correlation between these two parameters (r=0.109; p>0.05). Conclusion. In the patients with glaucoma, the retrobulbar part of the optic nerve is not thinner (it has normal values), even not in the cases with a totally excavated optic disc. There is no connection between the size of the PNO excavation and the thickness of the retrobulbar part of the optic nerve.


Author(s):  
Jigyasa Sahu

Aim: To describe a case of glaucoma which showed increase in optical coherence tomography (OCT) angiographic vessel densities after intraocular pressure reduction suggesting reperfusion of optic nerve. Presentation of Case: A 55 year old female with primary open angle glaucoma was taken up for trabeculectomy in view of inadequate control of intraocular pressure (IOP) despite maximal medical therapy. In addition to routine glaucoma assessment by visual fields and nerve fiber layer assessment by OCT, OCT angiographic evaluation of peripapillary vessel density was done preoperatively. Three months after trabeculectomy, her intraocular pressure decreased from 35mmHg to 14mmHg. Compared with the preoperative baseline value, the vessel density increased significantly in all quadrants after three months from surgery as demonstrated by OCT angiography. Discussion: This case report suggests that decreased optic nerve head perfusion due to high IOP can be reversed by reduction of IOP. Conclusion: Vascular parameters like angiographic vessel density can show reversible changes as decreased blood flow reinstates and thus can be better prognostic indicators than structural parameters like OCT retinal nerve fiber layer (RNFL) in glaucoma patients.


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