scholarly journals Angiolymphoid Hyperplasia with Eosinophilia with Clinical Presentation Concerning for Juvenile Temporal Arteritis

2019 ◽  
Vol 6 (1) ◽  
pp. 25-30
Author(s):  
Emily Li ◽  
John Sinard ◽  
Alberto Distefano ◽  
Mahsa Sohrab

A 20-year-old boy presented with a mass superotemporal to the right eyebrow of 1 month’s duration without a history of recent trauma. Complete examination and workup, including laboratory analysis, Doppler ultrasound imaging, and magnetic resonance imaging, suggested a diagnosis of juvenile temporal arteritis. Excisional biopsy and histopathology contradicted the preoperative workup and yielded the final diagnosis of angiolymphoid hyperplasia with eosinophilia, a rare eosinophilic dermatosis of unknown etiology. This case highlights the need for better characterization of temporal vascular tumors in the pediatric population.

Circulation ◽  
2010 ◽  
Vol 121 (8) ◽  
pp. 1045-1046 ◽  
Author(s):  
F. Grum ◽  
K. Hufendiek ◽  
S. Franz ◽  
U. Bogdahn ◽  
M.A. Gamulescu ◽  
...  

2018 ◽  
Vol 2 (3) ◽  

Background: A case of acute onset bilateral iridocyclitis is reported in a previously undiagnosed and asymptomatic case of sarcoidosis. Case: A 39 years old male presented with pain and redness in the right eye for one day. Slit lamp examination revealed granulomatous iridocyclitis in the eye with three hundred sixty degree posterior synechiae. While under investigation for the cause, on fourth day of initial presentation, left eye also developed similar granulomatous iridocyclitis, being symptomatic only overnight. All laboratory investigations, radiological evaluation and biopsy led to the final diagnosis of sarcoidosis. Conclusion: Sarcoidosis is a multisystem granulomatous disorder of unknown etiology which may present as an acute uveitis or chronic form. As definite prevalence studies are not available, it should be considered in the differential diagnosis of all cases of uveitis in Nepal.


2021 ◽  
Vol 10 (6) ◽  
pp. e26910615797
Author(s):  
Carlos Eduardo Nogueira Nunes ◽  
Anne Diolina Araújo Morais ◽  
João Victor Morais de Lima ◽  
Filipe Nobre Chaves ◽  
Marcelo Bonifácio da Silva Sampieri ◽  
...  

Peripheral odontogenic myxoma (POM) is a rare and extra-osseous variant of odontogenic myxoma (OM), classified as a relatively rare benign odontogenic tumor, yet presenting locally aggressive behavior. The objective this manuscript is to report a case of POM in a 75-year-old patient, located in the right maxilla, and in addition, to perform a literature review of the data in relation to clinical, radiographic aspects, hypothesis of diagnosis, and treatment. A male patient, 75 years old, clinical examination constact the presence of a nodule, with a smooth surface, on the right upper alveolar ridge, measuring 20 x 25 mm, with a color similar to the mucosa, a softened consistency, involving teeth 14 and 15, and with an undetermined time of evolution was observed. The diagnostic hypothesis was a peripheral ossifying fibroma and differential diagnosis of peripheral giant cell lesion. An excisional biopsy was performed together with extraction of the involved teeth. Histopathological examination and histochemical reaction was confirm the histopathological diagnosis of POM. The reported case is extremely rare due to the clinical presentation of the lesion, causing bone resorption with tooth mobility. In addition, the age range of involvement is very different from that presented in the literature, between the second and fourth decade of life. The final diagnosis was very important, as it is a lesion with a great potential for recurrence, long-term follow-up should be more careful, and in case of recurrence, a new intervention must be performed.


1996 ◽  
Vol 17 (4) ◽  
pp. 240-245 ◽  
Author(s):  
Debra M. Don ◽  
Akira Ishiyama ◽  
Anne K. Johnstone ◽  
Yao-shi Fu ◽  
Elliot Abemayor

2017 ◽  
Vol 2017 ◽  
pp. 1-4
Author(s):  
Hans-Ullrich Voelker ◽  
Daniel Kuehn ◽  
Annette Strehl ◽  
Stefan Kircher

Inflammatory myofibroblastic tumors (IMT) are distinctive lesions of unknown etiology, composed of myofibroblastic spindle cells with an associated inflammatory background. They can occur in a wide age range and at all anatomic sites, but most frequently they can be observed in the lung (especially in pediatric cases), abdomen, or retroperitoneum. The urinary bladder is one of the most common sites in urological cases. We present a very rare case of IMT of the testis. Clinically, a 40-year-old patient showed a palpable painless lesion of the right testis. Ultrasound examination showed two solid intratesticular foci. During surgical intervention, the intraoperative frozen section revealed mesenchymal tumors admixed with an uncommon inflammatory infiltrate, consistent with a reorganized abscess. Despite the benign result, orchiectomy was performed due to the multifocal presentation and the large size of 3 cm. The final diagnosis was IMT without ALK-rearrangement. Incomplete resection increases the risk of local relapses to 30%. In this case, a complete resection could be achieved and the patient is free of tumor 15 months later.


2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Ghazal Ansari ◽  
Angela Pakozdi ◽  
Oseme Etomi

Abstract Introduction A 32-year-old man presented to rheumatology clinic with a 2-year history of progressively worsening right temporal headache, a painful hard lump on his right temple and pre-auricular tenderness not responding to conventional analgesics. Patient denied any jaw and tongue claudication. His vision was not compromised and patient denied weight loss, night sweats and arthralgia. He was fit and well otherwise. Case description Examination revealed a pulsatile mass with a length of 1 cm along the superficial temporal artery. Temporal artery ultrasound revealed lump corresponds to the superficial artery with thickened wall and halo formation raising the possibility of temporal arteritis. MRI head scan suggested inflammation of the superficial temporal artery. Discussion Because of the atypical features of young age and normal inflammatory markers, corticosteroid treatment was not commenced. A temporal artery biopsy showed no evidence of vasculitis, but revealed reactive lymphoid follicles with eosinophil infiltrates in the surrounding soft tissue. The diagnosis of angiolymphoid hyperplasia with eosinophilia (ALHE) was made. The patient’s headaches have completely resolved after the temporal biopsy. Unfortunately, three months later the lump and the headaches recurred. The symptoms improved with topical tacrolimus 0.1% ointment and he underwent for complete surgical excision of the lump. Patient is asymptomatic and remained well. Key learning points We present a case of angiolymphoid hyperplasia with eosinophilia which can mimic temporal arteritis presentation as in our case and has totally different approach to management.  ALHE, which is a benign, locally proliferative condition with predilection to the periauricular and scalp area with no definitive treatment however, complete excision can be curative. It may recur in up to one-third of cases in the absence of complete surgical excision as in our patient. Conflict of interest The authors declare no conflicts of interest.


2021 ◽  
Vol 26 (1) ◽  
Author(s):  
Jiang Huajun ◽  
Qu Wei ◽  
Wu Yuxuan ◽  
Yang Jingjing

Abstract Background Intraosseous schwannomas are extremely rare in the humerus, and less than five cases have been reported previously in the literature. This is the first report of its origin in the proximal humerus with pathologic fracture. We herein present this case to discuss the reason for its rarity and share our experience of management. Case presentation A 55-year-old female patient presented with pain in the right shoulder, which was caused by tripping and falling over a board. Radiographs, computed tomography (CT) and magnetic resonance imaging (MRI) showed considerable tumor in proximal humerus, which connected with a fracture. For this suspected tumor, we performed two operations. Pathological examination demonstrated typical picture of a schwannoma, showing whorls and interlacing fascicles of schwannoma spindle cells. Immunohistochemistry, the tumor cells were diffusely positive for S-100 protein, SOX-10 and CD68, while they were completely negative for desmin, DOG-1, AE1/AE3 and P63. The Ki-67 index was about 10%. No mitoses or features of malignancy were identified. The final diagnosis of intraosseous schwannoma was made. The treatment for intraosseous schwannoma with pathologic fracture includes excisional biopsy, curettage, bone allograft, and fracture fixation. The patient recovered well. After the surgery, the patient gradually regained mobility and the pain subsided. There was no recurrence after 6 months of follow-up by X-ray. Conclusions Although very rare, intraosseous schwannoma should be taken under consideration in the differential diagnosis of benign-appearing osseous tumor in the proximal humerus with pathologic fracture.


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