scholarly journals Primary Conjunctival Pigmented Basal Cell Carcinoma with Increased Numbers of Intra-Tumour Melanocytes, Mimicking Melanoma: A Case Report and Review of the Literature

2019 ◽  
Vol 6 (3) ◽  
pp. 168-173
Author(s):  
Hardeep Singh Mudhar ◽  
Soma Rani Roy ◽  
Murtuza Nuruddin ◽  
Fahmida Hoque

A 60-year-old, South-Asian male patient presented with a dark brown lesion on his left conjunctiva surface near the limbus for 2 years. Examination showed a globular, dark brown-coloured mass near the temporal limbus at 4 to 5 o’clock position, measuring 3 × 3 × 2 mm. There were a few scattered flat pigmented lesions near the mass and also a few prominent vessels. The mass underwent wide local excision, with a clear margin, followed by double freeze cryotherapy of the conjunctival margins along with the application of Mitomycin C. The bare sclera was covered by amniotic membrane. Histology surprisingly revealed a nodular basal cell carcinoma (BCC) containing melanin. The melanin was present in the tumour cell cytoplasm, within melanophages and within dendritic, Melan A-positive melanocytes. The BCC was immunohistochemically positive for BerEP4 and negative for EMA. The clinically observed smaller nodules flanking the main pigmented BCC corresponded histologically to pigmented superficial growth pattern BCC connected to the under surface of the conjunctival epithelium. This is the first report of a pigmented BCC of the conjunctiva, mimicking a conjunctival melanoma. Pigmented BCC should be considered in the differential diagnosis of pigmented tumours of the conjunctiva.

Hand Surgery ◽  
2002 ◽  
Vol 07 (02) ◽  
pp. 295-298 ◽  
Author(s):  
M. Galeano ◽  
M. Colonna ◽  
M. Lentini ◽  
F. Stagno D'Alcontres

Basal cell carcinoma (BCC) is the most common skin malignancy arising from cells of the basal layer of the epithelium or from the external root sheath of the hair follicle. BCC of the digit is a rare entity. The article presents one such case of bowenoid BCC of the thumb which required amputation at the MP joint.


Author(s):  
Anna Mleczko ◽  
Ingolf Franke ◽  
Anna Pokrywka ◽  
Harald Gollnick ◽  
Martin Leverkus

2021 ◽  
Vol 22 (4) ◽  
Author(s):  
Cornel Petreanu ◽  
Elena-Daniela Șerban ◽  
Maria-Magdalena Constantin ◽  
Cornel Savu ◽  
Alexandru Zariosu ◽  
...  

2007 ◽  
Vol 116 (9) ◽  
pp. 663-666 ◽  
Author(s):  
Ilka Charlotte Naumann ◽  
Susan R. Cordes

Basal cell carcinoma (BCC) is the most common malignant skin lesion and is frequently curatively treated with local excision. Improper removal or neglect of BCC is a particular problem for head and neck surgeons. We describe a case of a recurrent BCC that aggressively grew from the forehead skin through the skull and into the frontal lobe. We also present a review of the literature. Despite its fairly benign growth pattern, BCC should never be underestimated, and care should be taken not only in the complete primary excision but also in cancer surveillance.


1993 ◽  
Vol 19 (2) ◽  
pp. 137-139 ◽  
Author(s):  
DANIEL BENHARROCH ◽  
DAVID B. GEFFEN ◽  
JOHANAN PEISER ◽  
LIOR ROSENBERG

2000 ◽  
Vol 79 (7) ◽  
pp. 511-519 ◽  
Author(s):  
James P. Malone ◽  
Fred G. Fedok ◽  
Deborah A. Belchis ◽  
Mary E. Maloney

2011 ◽  
Vol 3 (3) ◽  
pp. 37 ◽  
Author(s):  
Marie Caucanas ◽  
Gebhard Müller ◽  
Olivier Vanhooteghemv

2008 ◽  
Vol 61 (1) ◽  
pp. 65-70 ◽  
Author(s):  
Ulrich M. Rieger ◽  
Daniel F. Kalbermatten ◽  
Reto Wettstein ◽  
Ilonka Heider ◽  
Martin Haug ◽  
...  

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