Fine-Needle Aspiration Cytology Is an Effective Diagnostic Tool in Paediatric Patients with Mucoepidermoid Carcinoma as Secondary Neoplasm

2020 ◽  
Vol 64 (6) ◽  
pp. 520-531 ◽  
Author(s):  
Andrea Ronchi ◽  
Martina Di Martino ◽  
Alessandro Caputo ◽  
Pio Zeppa ◽  
Giuseppe Colella ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Fine Needle Aspiration ◽  
Diagnostic Tool ◽  
Fine Needle Aspiration Cytology ◽  
Mucoepidermoid Carcinoma ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Paediatric Patients ◽  
Needle Aspiration Cytology

<b><i>Background:</i></b> Mucoepidermoid carcinoma (MEC) is the most common malignant salivary gland tumour in paediatric population, accounting for 16% of all cases. Patients affected by a previous solid or leukaemic neoplasm during their childhood may develop a second different tumour during the follow-up. In this setting, salivary gland MEC is relatively frequent, accounting for 6% of the second neoplasms in paediatric patients. Consequently, the occurrence of salivary gland nodules in paediatric patients with a previous neoplasm should be considered an event with a high risk of malignancy that poses peculiar diagnostic challenges. <b><i>Summary:</i></b> This study was designed to define clinical and instrumental findings and morphological features of MEC on fine-needle aspiration cytology (FNAC) samples in paediatric patients with and without a previous neoplasm. Five patients under 19 years are included in this series. FNAC was performed in all patients on a parotid nodule. We have identified 2 groups of patients: (a) 2 cases with previous history of malignancy (acute lymphoblastic leukaemia and Hodgkin lymphoma) and (b) 3 cases without previous malignant neoplasms. In all cases, a final diagnosis of MEC was rendered. <b><i>Key Messages:</i></b> MEC may occur as a second malignancy in paediatric patients. FNAC is certainly a valid and accurate diagnostic tool for this type of neoplasm, even in the paediatric age, allowing the correct management of the patients.

Profile of Fine-Needle Aspiration Cytology (FNAC) of Salivary Gland Lesions with Histopathological Correlation in a Tertiary Care Hospital of Maharashtra

2021 ◽  
Vol 8 (14) ◽  
pp. 893-898
Author(s):  
Pradip Ramabhau Butale ◽  
Sagar Jagdish Gawai
Keyword(s):  
Salivary Gland ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Mucoepidermoid Carcinoma ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Histopathological Correlation ◽  
Neoplastic Lesions ◽  
Needle Aspiration Cytology

BACKGROUND Fine needle aspiration cytology (FNAC) is a method for the diagnosis of superficial lesions like swellings of the salivary glands since many years. The present study was undertaken to identify the patterns of salivary gland lesions (SGL) on FNAC and histopathology specimens and also describe the age and sex distribution of SGL. METHODS A total 319 cases of SGL were studied from June 2009 to July 2019 which included both retrospective and prospective cases. A detailed history was taken, clinical and necessary laboratory investigations were done; and then FNAC of salivary gland was done. Histopathology examination of specimens was done whenever available; FNAC and histopathology slides of retrospective cases were reviewed. Correlation between cytomorphology and histomorphology was done only where available. RESULTS The majority of cases was in the age group of 21 - 40 years (42.98 %) with female predominance (53 %) and commonest gland involved was parotid gland (52.97 %) in both the sexes. 138 (43 %) cases were non-neoplastic lesions and 181 (57 %) were diagnosed as neoplastic lesions. Of the 138 non neoplastic lesions, on cytology and histopathology, sialadenitis constituted 110 (79.71 %) cases; most being chronic sialadenitis (107). Out of 181 neoplastic lesions, 142 (77.78 %) were benign while 39 (22.22 %) cases were malignant. Pleomorphic adenoma was the commonest benign neoplasm (71.27 %) and mucoepidermoid carcinoma (66.69 %) was the commonest malignant neoplasm. Histopathological correlation was available in 37 cases. CONCLUSIONS FNAC is useful as an outdoor diagnostic procedure because of the availability of earlier diagnosis in comparison with the histopathological diagnosis. Histopathology correlation is helpful in cases where diagnosis at FNAC is difficult. KEYWORDS FNAC, Salivary Glands, Histopathology, Specimens, Cytomorphology, Sialadenitis, Pleomorphic Adenoma, Mucoepidermoid Carcinoma

Dermal Analogue Tumor of the Salivary Gland Diagnosed by Fine Needle Aspiration Cytology

2004 ◽  
Vol 48 (1) ◽  
pp. 78-82 ◽  
Author(s):  
Jesùs Vera-Alvarez ◽  
Miguel Marigil-Gómez ◽  
María Dolores García-Prats ◽  
Manuel Abascal-Agorreta ◽  
Miguel Lacasa-Laliena ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology

scholarly journals A comparative study of fine-needle aspiration cytology and histopathology in salivary gland lesions

1970 ◽  
Vol 1 (2) ◽  
pp. 108-113 ◽  
Author(s):  
S Vaidya ◽  
A Sinha ◽  
S Narayan ◽  
S Adhikari ◽  
KC Sabira
Keyword(s):  
Salivary Gland ◽  
Diagnostic Accuracy ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Neoplastic Lesions ◽  
Needle Aspiration Cytology ◽  
Sensitivity Specificity

Background: A wide variety of benign and malignant tumours originate in the salivary glands and insufficient tumour cells make their diagnosis difficult in some patients. The aim of this study was to evaluate the efficacy of fine-needle aspiration cytology in the diagnosis of salivary gland lesions and to correlate cytological findings with histopathology. Materials and Methods: This was a prospective study done from September 2002 to May 2004. Fine needle aspiration cytology was performed in 58 patients with clinically significant salivary gland masses. Results: Fine needle aspiration cytology categorized 67.24% of the salivary gland lesions as neoplastic and 32.76% as non-neoplastic lesions. Amongst the neoplastic lesions, 76.9% were benign and 23.1% were malignant cases. Histopathological examination revealed that 81.05% of the cases were benign and 18.95% were malignant. Fine needle aspiration cytology had a sensitivity, specificity and diagnostic accuracy of 81.82%, 100% and 96.55%, respectively. The positive predictive value and negative predictive value was 100% and 95.9%, respectively. Conclusion: Fine needle aspiration of the salivary gland is a safe and reliable technique in the primary diagnosis of salivary gland lesions. Although, limitations are encountered while predicting specific lesions on cytology, especially when dealing with cystic and some malignant lesions, this study has shown that fine needle aspiration cytology has a high sensitivity, specificity and diagnostic accuracy in diagnosing salivary gland lesions. Keywords: Salivary glands; Fine needle aspiration cytology; Histopathology DOI: http://dx.doi.org/10.3126/jpn.v1i2.5403 JPN 2011; 1(2): 108-113

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