scholarly journals Intravitreal Voriconazole for Treatment of Bilateral Endogenous Candida Chorioretinitis

2020 ◽  
Vol 11 (2) ◽  
pp. 402-410 ◽  
Author(s):  
Ha Eun Sim ◽  
Min Ji Kang ◽  
Jae Suk Kim ◽  
Je Hyung Hwang
Keyword(s):  
Optical Coherence Tomography ◽  
Candida Albicans ◽  
Intravitreal Bevacizumab ◽  
Retinal Hemorrhage ◽  
Fundus Photography ◽  
Fundus Examination ◽  
Blurred Vision ◽  
Intravitreal Bevacizumab Injection ◽  
History Of ◽  
Bevacizumab Injection

This report describes a patient with bilateral endogenous candida chorioretinitis. The patient had a 2-day history of bilateral blurred vision. Fundus photography revealed multiple chorioretinal infiltrations in both eyes and a parafoveal hemorrhage in the left eye. After 2 days, fundus examination showed an increased number of infiltrations and hemorrhages in both eyes and worsening vitreous inflammation. A large infiltrative intraretinal lesion and a retinal hemorrhage of the left eye were discovered on optical coherence tomography. Candida albicans was diagnosed from blood culture. The bilateral candida chorioretinitis had not responded to systemic or topical antifungal medication. The chorioretinitis was refractory to intravitreal amphotericin B as well. Intravitreal voriconazole injection in both eyes and intravitreal bevacizumab injection in the left eye were performed thereafter. The chorioretinal infiltrations and hemorrhages decreased in both eyes. Intravitreal voriconazole injection was effective in the treatment of intractable candida chorioretinitis.

scholarly journals Bilateral idiopathic choroidal folds

2014 ◽  
Vol 155 (27) ◽  
pp. 1083-1086
Author(s):  
Milán Tamás Pluzsik ◽  
Miklós Schneider
Keyword(s):  
Optical Coherence Tomography ◽  
Visual Acuity ◽  
Fluorescein Angiography ◽  
Fundus Photography ◽  
Fundus Examination ◽  
Optical Coherence ◽  
Blurred Vision ◽  
History Of ◽  
Choroidal Folds

Choroidal folds present as parallel bright and dark lines, which may be detected with funduscopy. Optical coherence tomography, red free fundus photography, autofluorescence and fluorescein angiography may be also helpful to establish the diagnosis. The authors present the case of a 70-year-old male who was evaluated because of a 1-month history of blurred vision on his right eye. Dilated fundus examination revealed choroidal folds in both eyes, which failed to affect visual acuity. No neurogical pathologies were found. There was no change in the patient condition durind a follow-up period of 6 months. The authors note that choroidal folds are often not recognized because they are usually asymptomatic. There are several possible causes which should be considered. The diagnosis of idiopathic choroidal folds is based on the exclusion of other pathologies. Observation of the patient’s visual acuity and monitoring for fundus changes are needed. Orv. Hetil., 2014, 155(27), 1083–1086.

scholarly journals Prompt Response to single injection of Bevacizumab in a case of Fibrinous Central Serous Choroidopathy (CSC).

2017 ◽  
Vol 16 (1) ◽  
pp. 157-160
Author(s):  
Balbir Khan ◽  
Rajwinder Kaur ◽  
Vartika Anand ◽  
Prithpal S Matreja
Keyword(s):  
Therapeutic Option ◽  
Pigment Epithelium ◽  
Retinal Pigment ◽  
Serous Retinal Detachment ◽  
Medical Science ◽  
Subretinal Fluid ◽  
Intravitreal Bevacizumab ◽  
Fundus Photography ◽  
Intravitreal Bevacizumab Injection ◽  
Bevacizumab Injection

Purpose: Central Serous Choroidopathy (CSC) is a disease of young and middle aged adults as a localized detachment of the neurosensory retina. Though the cause of CSC remains unknown, it is believed that abnormalities in choroidal circulation make overlying retinal pigment epithelium dysfunctional, resulting in development of a serous retinal detachment. Subretinal fibrin accumulation is rare but vision threatening association of CSC.Methods: A young 31 years female with acute central serous chorioretinopathy received an Intravitreal bevacizumab (1.25 mg/0.05 ml) injection. At baseline and follow-up visits, patients had best corrected visual acuity (BCVA), IOP assessment, dilated fundus examination, fundus photography, fluorescein angiography (FA), and Optical Coherence Topography(OCT) imaging.Results: Patient showed resolution of fibrin, resolution of intraretinal or subretinal fluid promptly, and improvement in visual symptoms and acuity within 1 month. At 6 months patient is maintaining 20/20 vision without any recurrence.Conclusions: Intravitreal bevacizumab injection for acute fibrinous central serous choroidopathy may result in prompt resolution of neurosensory detachment and reduction of angiographic leakage. These short-term results suggest that Intravitreal bevacizumab injection may constitute a promising therapeutic option in fibrinous central serous chorioretinopathy.Bangladesh Journal of Medical Science Vol.16(1) 2017 p.157-160

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