scholarly journals Multifocal Urinary Tract Metastasis of Colorectal Carcinoma

Pathobiology ◽  
2021 ◽  
pp. 1-7
Author(s):  
Zsuzsanna Fejes ◽  
István Előd Király ◽  
Ádám Miklós Fehér ◽  
Péter György Kovács ◽  
Zoltán Gyuris ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Colorectal Carcinoma ◽  
Prostate Gland ◽  
Upper Urinary Tract ◽  
Primary Adenocarcinoma ◽  
Direct Invasion ◽  
Pathologic Features ◽  
Ureteral Tumor ◽  
Histological Processing ◽  
Metastatic Involvement

<b><i>Introduction:</i></b> Secondary urinary tract tumors are uncommon findings and mainly evolve by direct invasion from adjacent organs. Actual metastatic involvement often develops in the urinary bladder, while the upper urinary tract is infrequently affected. In addition, the lungs, breast, and prostate gland are the usual primary sites. Colorectal carcinoma (CRC) may spread to the ureter directly or seeds via vascular or lymphatic channels. It may pose struggles in the differential diagnosis because CRC shares standard pathologic features with the primary adenocarcinoma of the urinary tract. <b><i>Case Presentation:</i></b> We describe the case of an 81-year-old man who was referred to our hospital with a distal ureteral tumor that was treated by a ureteronephrectomy. The histopathological and genetic analysis established the diagnosis of metastatic CRC along with 3 metastases in the renal pelvis. <b><i>Conclusion:</i></b> This rare case highlights the limitations of conventional histological processing, including immunohistochemistry, and it underlines the role of molecular investigations in certain circumstances.

Pathologic Features of Recurrent Bladder Tumors after Upper Urinary Tract Transitional Cell Carcinoma

2008 ◽  
Vol 49 (6) ◽  
pp. 502
Author(s):  
Nam Seok Lee ◽  
Sung Dae Kim ◽  
Dong Wan Sohn ◽  
Sae Woong Kim ◽  
Yong-Hyun Cho
Keyword(s):  
Urinary Tract ◽  
Transitional Cell Carcinoma ◽  
Cell Carcinoma ◽  
Transitional Cell ◽  
Upper Urinary Tract ◽  
Bladder Tumors ◽  
Pathologic Features

989: Pathologic Features of Bladder Tumors Following Upper Urinary Tract Transitional Cell Carcinoma

2006 ◽  
Vol 175 (4S) ◽  
pp. 319-319
Author(s):  
Jay D. Raman ◽  
R. Ernest Sosa ◽  
E. Darracott Vaughan ◽  
Douglas S. Scherr
Keyword(s):  
Urinary Tract ◽  
Transitional Cell Carcinoma ◽  
Cell Carcinoma ◽  
Transitional Cell ◽  
Upper Urinary Tract ◽  
Bladder Tumors ◽  
Pathologic Features

Micropapillary Variant of Urothelial Carcinoma in the Upper Urinary Tract: A Clinicopathologic Study of 11 Cases

2009 ◽  
Vol 133 (1) ◽  
pp. 62-66 ◽  
Author(s):  
Charles C. Guo ◽  
Pheroze Tamboli ◽  
Bogdan Czerniak
Keyword(s):  
Urinary Tract ◽  
Urothelial Carcinoma ◽  
Lymphovascular Invasion ◽  
Clinical Course ◽  
Clinical Information ◽  
Distant Metastases ◽  
Upper Urinary Tract ◽  
Clinicopathologic Study ◽  
Pathologic Features

Abstract Context.—Micropapillary urothelial carcinoma (MPUC) is a rare variant of urothelial carcinoma. Most studies of MPUC have focused on the urinary bladder, but MPUC of the upper urinary tract remains to be investigated. Objective.—To investigate the pathologic features and clinical significance of MPUC in the upper urinary tract. Design.—We searched the pathology files at our institution and identified 11 cases of MPUC of the upper urinary tract. The histology slides were reviewed, and the clinical information was obtained by review of medical charts. Results.—The average age of the patients was 64.2 years (range, 22–76 years). The tumors were located in the renal pelvis (n = 5), ureter (n = 4), and ureteropelvic junction (n = 2). In all cases, MPUC accounted for an average of 45% (range, 10%–80%) of the tumor and was associated with conventional urothelial carcinoma. Lymphovascular invasion was present in all cases, and metastasis to lymph node was present in 4 of 5 patients whose lymph nodes were dissected. Two patients presented with pT2 disease, and both were alive without evidence of disease at 85 and 119 months after surgery. The other 9 patients presented with pT3 or pT4 disease: 4 of them died of disease at an average of 18 months; 4 surviving patients developed distant metastases; and 1 surviving patient with limited follow-up (6 months) showed no evidence of disease. Conclusions.—Micropapillary urothelial carcinoma of the upper urinary tract often presents at an advanced stage with lymphovascular invasion and distant metastasis. The presence of MPUC, even focal, indicates a poor clinical course.

scholarly journals Metachronous Primary Adenocarcinoma of Distal and Proximal Ureter within Two Years

2014 ◽  
Vol 2014 ◽  
pp. 1-3
Author(s):  
Dominik Abt ◽  
Gautier Müllhaupt ◽  
Livio Mordasini ◽  
Pierre André Diener ◽  
Hans-Peter Schmid
Keyword(s):  
Urinary Tract ◽  
Urinary Tract Obstruction ◽  
Upper Urinary Tract ◽  
Primary Adenocarcinoma ◽  
R0 Resection ◽  
Rare Entity ◽  
Distal Ureter ◽  
First Case ◽  
Proximal Ureter ◽  
Low Incidence

Primary adenocarcinoma of the upper urinary tract, particularly of the ureter, is an extremely rare entity. We are reporting on the first case of metachronous appearance in one patient. The 71-year-old man underwent partial ureterectomy (R0 resection) for primary adenocarcinoma of the left distal ureter. 3 years later, nephroureterectomy had to be performed because of metachronous primary adenocarcinoma of the left proximal ureter. Extensive examinations revealed no evidence for further malignancies at both times. Primary adenocarcinoma of the upper urinary tract is rare but should be kept in mind, especially in patients with chronic inflammation and urinary tract obstruction. Due to the low incidence, there is a lack of data regarding its pathogenesis, diagnosis, and optimal treatment.

UPPER URINARY TRACT CHOLESTEATOMA MISDIAGNOSED AS A URETERAL TUMOR

2000 ◽  
pp. 120-121
Author(s):  
WON HEE PARK ◽  
HYEONG GON KIM ◽  
YUN CHAN CHOI ◽  
HYEON GYEOM KIM ◽  
JE HEE KIM ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Upper Urinary Tract ◽  
Ureteral Tumor

scholarly journals Comparative analysis of patients with upper urinary tract urothelial carcinoma in black-foot disease endemic and non-endemic area

2020 ◽  
Author(s):  
Che-Wei Chang ◽  
Chien-Hui Ou ◽  
Chih-Chin Yu ◽  
Chi-Wen Lo ◽  
Chung-You Tsai ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Urothelial Carcinoma ◽  
Water Contamination ◽  
Disease Free Survival ◽  
Upper Urinary Tract ◽  
Survival Curves ◽  
Free Survival ◽  
Ureteral Tumor ◽  
Disease Free ◽  
Urinary Tract Urothelial Carcinoma

Abstract Objective High incidence of upper urinary tract urothelial carcinoma has been reported in South- Western area of Taiwan, where arsenic water contamination was considered to be the main cause. However, there is no definite proof to show the correlation between the arsenic water contamination and upper urinary tract urothelial carcinoma. To investigate the clinical and epidemiological features of the patients with upper urinary tract urothelial carcinoma between arsenic water endemic and non-endemic areas, we analyzed patients in terms of characteristics, stratified overall survival, disease-free survival and cancer-specific survival Method The records of a total 1194 patients diagnosed with upper urinary tract urothelial carcinoma were retrospectively reviewed. Clinical data and current medical status were collected from medical records. Statistical analyses were performed to determine the clinical variables and stratified survival curves between endemic and non-endemic groups. Results Female predominance was revealed in both endemic and non-endemic groups (Male:Female=1:1.2- 1.4). No statistical differences were found in histological types, staging and tumor size among two groups. Nonetheless, patients with characteristics of aging and having end stage renal disease outnumbered in non-endemic group while higher prevalence of previous bladder tumor and more ureteral tumor were found in endemic group. Adjusted stratified cumulative survival curves suggested poorer prognosis fashion in endemic patients, especially in disease free survival of early stage disease. Conclusions Higher mortality rate with more previous bladder cancer history and ureteral tumor were seen in patients with upper urinary tract urothelial carcinoma residing in arsenic water contamination area. This may attribute to the long-term carcinogenesis effect of arsenic underground water.

UPPER URINARY TRACT CHOLESTEATOMA MISDIAGNOSED AS A URETERAL TUMOR

2000 ◽  
Vol 164 (1) ◽  
pp. 120-121 ◽  
Author(s):  
WON HEE PARK ◽  
HYEONG GON KIM ◽  
YUN CHAN CHOI ◽  
HYEON GYEOM KIM ◽  
J.E. HEE KIM ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Upper Urinary Tract ◽  
Ureteral Tumor

Simultaneous Antegrade/Retrograde Upper Urinary Tract Access: Bart's Modified Lateral Position for Complex Upper Tract Endourologic Pathologic Features

Urology ◽  
2012 ◽  
Vol 79 (2) ◽  
pp. 287-292 ◽  
Author(s):  
Konstantinos Moraitis ◽  
Prodromos Philippou ◽  
Tamer El-Husseiny ◽  
Hassan Wazait ◽  
Junaid Masood ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Lateral Position ◽  
Upper Urinary Tract ◽  
Upper Tract ◽  
Pathologic Features
Sign in / Sign up

Export Citation Format

Share Document