Comprehensive risk reduction in patients with atrial fibrillation: Emerging diagnostic and therapeutic options

2011 ◽  
Vol 106 (12) ◽  
pp. 1012-1019. ◽  
Author(s):  
Gregory Lip ◽  
Isabelle Van Gelder ◽  
Jeroen Bax ◽  
Elaine Hylek ◽  
Stefan Kääb ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Heart Rhythm ◽  
Consensus Conference ◽  
Risk Markers ◽  
Summary Report ◽  
Competence Network ◽  
Executive Summary ◽  
New Developments ◽  
Esc Guidelines

SummaryThere are exciting new developments in several areas of atrial fibrillation (AF) management that carry the hope of improving outcomes in AF patients. This paper is an executive summary that summarises the proceedings from the 3rd AFNET/EHRA consensus conference on atrial fibrillation, held in Sophia Antipolis from November 7th to 9th 2010, shortly after the release of the new ESC guidelines on AF. The conference was jointly organised by the German Atrial Fibrillation competence NETwork (AFNET) and the European Heart Rhythm Association (EHRA). This executive summary report covers four sections: 1. Risk factors and risk markers for AF, 2. Pathophysiological classification of AF, 3. Relevance of monitored AF duration for AF-related outcomes, and 4. Perspectives and needs for implementing better antithrombotic therapy.

scholarly journals Peripheral blood leukocyte telomere length as a possible prognostic marker for the development of atrial fibrillation

2020 ◽  
Vol 11 (2) ◽  
pp. 50-54
Author(s):  
Svetlana Yu. Nikulina ◽  
Ksenya Yu. Shihkova ◽  
Vladimir A. Shulman ◽  
Anna A. Chernova ◽  
Vladimir N. Maksimov
Keyword(s):  
Atrial Fibrillation ◽  
Telomere Length ◽  
Heart Rhythm ◽  
Peripheral Blood Leukocyte ◽  
Response To Therapy ◽  
Leukocyte Telomere Length ◽  
Risk Markers ◽  
Heart Rhythm Disorders ◽  
Blood Leukocyte

Atrial fibrillation is one of the most common heart rhythm disorders. The most prominent risk factor for atrial fibrillation is advanced age. Population ageing contributes to an increase in both the prevalence of this pathology and socio-economic burden of the disease for society in general and the patient in particular. Adequate therapy and prevention of atrial fibrillation requires the search for novel prognostic risk markers for disease development, progression, and patients response to therapy. One of these markers is the length of telomeres structures at the ends of chromosomes that protect them from degradation during cell division. The article provides an overview of world studies, both confirming and disproving the role of leukocyte telomere length in atrial fibrillation development.

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