scholarly journals Ulceration and Stenosis of Internal Carotid Artery Imaged by Convergent Color Doppler

Circulation ◽  
1999 ◽  
Vol 100 (17) ◽  
Author(s):  
Katsufumi Mizushige ◽  
Hideo Ohyama ◽  
Masaya Kitadai ◽  
Shoichi Senda ◽  
Hirohide Matsuo
1989 ◽  
Vol 152 (6) ◽  
pp. 1299-1305 ◽  
Author(s):  
SJ Erickson ◽  
MW Mewissen ◽  
WD Foley ◽  
TL Lawson ◽  
WD Middleton ◽  
...  

Stroke ◽  
2016 ◽  
Vol 47 (suppl_1) ◽  
Author(s):  
Soichiro Abe ◽  
Kozue Saito ◽  
Hatsue Ishibashi-Ueda ◽  
Shuichi Tonomura ◽  
Kota Mori ◽  
...  

Background: The ulcerated atheroma of the carotid artery is a risk factor of ipsilateral ischemic stroke. Contrast-enhanced ultrasound (CEUS) is a novel noninvasive technique useful for evaluating the morphology of carotid plaques, and can detect small disruptions on plaque surface. However, it remains unclear whether the disrupted carotid plaque detected by CEUS is related to the symptomatic internal carotid artery stenosis (ICS). Methods: A total of 79 ICS patients who underwent carotid endarterectomy (CEA) were enrolled from July 2010 to July 2015. Before operation, ICA lesions were examined by color Doppler ultrasound (CDUS) and CEUS using perflubutane. The ulceration was diagnosed when both of the color Doppler signal on CDUS and the pooling of microbubbles on CEUS were observed within the plaque. The disruption was diagnosed only by CEUS when microbubbles pooled through the fissured surface, unlike the linear delineation of neovessels. We validated findings on ultrasound compared with the histopathological findings of ulceration and present/recent plaque rupture. The associations between ulceration/disruption on ultrasound and symptomatic ICS (with a history of ipsilateral transient ischemic attack and/or ischemic stroke) were investigated. Results: Of 79 subjects (mean age 71.2±6.8 years old, 78 men), 55 had symptomatic ICS. The ulceration by CEUS and CDUS was recognized in 20 patients (25%), and the disruption on plaque surface was seen by CEUS solitary in 26 patients (33%). The sensitivity and specificity of detecting plaque ulceration or disruption using CEUS compared with histopathological findings were 0.57 (45/66) and 1.00 (13/13), respectively. The detection rate of ulceration or disruption using CEUS was higher in symptomatic ICS than in asymptomatic ICS (66% vs 42%, P=0.049). Compared to plaques without ulceration/disruption on ultrasound, prevalence of symptomatic ICS was higher in plaques with the disruption (88% vs 58%, P=0.01), whereas it was similar in plaques with the ulceration (65% vs 58%, P=0.77) Conclusion: Small disruptions on carotid plaque surface detected by CEUS were significantly related to symptomatic ICS and this results may help the detailed assessment of plaque vulnerability.


Author(s):  
Ulrich Sliwka ◽  
Peter Schmidt ◽  
Jürgen Reul ◽  
Johannes Noth

Neurosurgery ◽  
2001 ◽  
Vol 48 (2) ◽  
pp. 328-333 ◽  
Author(s):  
Shoichiro Kawaguchi ◽  
Shuzo Okuno ◽  
Toshisuke Sakaki ◽  
Norikiyo Nishikawa

Abstract OBJECTIVE We evaluated the effect of carotid endarterectomy on chronic ocular ischemic syndrome due to internal carotid artery stenosis by use of data obtained from ophthalmic artery color Doppler flow imaging. METHODS We examined 11 patients with ocular ischemic syndrome due to internal carotid artery stenosis (>70% stenosis) who were being treated by carotid endarterectomy. Ophthalmic artery color Doppler flow imaging indicated ophthalmic artery flow direction and peak systolic flow velocity and was performed before and at 1 week, 1 month, and 3 months after surgery. RESULTS We assessed the ophthalmic arteries of 11 patients via color Doppler flow imaging. Before undergoing carotid endarterectomy, five patients showed reversed ophthalmic artery flow. In the other six patients who experienced antegrade ophthalmic artery flow, the average peak systolic flow velocity was 0.09 ± 0.05 m/s (mean ± standard deviation). Preoperative reversed flow resolved in each patient 1 week after undergoing surgery. All patients showed antegrade ophthalmic artery flow. The average peak systolic flow velocity in the patients who had preoperative antegrade flow rose significantly, to 0.21 ± 0.14 m/s (P < 0.05). There was no significant change as compared with findings at 1 week after surgery. During the follow-up period (mean, 32.4 mo), no patients complained of recurrent visual symptoms. At the end of the study period, visual acuity had improved in five patients and had not worsened in the other six patients. CONCLUSION Carotid endarterectomy was effective for improving or preventing the progress of chronic ocular ischemia caused by internal carotid artery stenosis.


Congenital absence of the internal carotid artery is a rare anomaly, occurring in less than 0.01% of the population [1, 3]. It includes agenesis, aplasia, and hypoplasia of the internal carotid artery [2, 5]. Recognition of these anomalies has important implications during planned surgery, in thromboembolic disease and in the surveillance and detection of associated cerebral aneurysms [2, 3]. It is usually an incidental finding on color Doppler carotid ultra sonography, angiography, computed tomography or magnetic resonance imaging of the head and neck taken for some other indication [2, 6]. Most of the patients are asymptomatic due to the presence of sufficient cerebral circulation supplied by the communicating arteries of the circle of Willis, inter cavernous anastomosis, external carotid artery and by persistent embryologic arteries to the carotid artery territory. Nevertheless, in some cases this anatomic variation may eventually lead to some clinical signs and symptoms [2, 4, 6]. We present a rare case of congenital absence of both internal carotid arteries and its possible implications.


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