Serum Cardiac Troponin T and Creatine Kinase–MB Elevations in Murine Autoimmune Myocarditis

Circulation ◽  
1995 ◽  
Vol 92 (7) ◽  
pp. 1927-1932 ◽  
Author(s):  
Kurt Bachmaier ◽  
Johannes Mair ◽  
Felix Offner ◽  
Christian Pummerer ◽  
Nikolaus Neu
Keyword(s):  
Creatine Kinase ◽  
Cardiac Troponin ◽  
Troponin T ◽  
Cardiac Troponin T ◽  
Autoimmune Myocarditis ◽  
Creatine Kinase Mb ◽  
Serum Cardiac Troponin

scholarly journals A comparison of cardiac troponin T and creatine kinase-MB for patient evaluation after cardiac surgery

2002 ◽  
Vol 39 (9) ◽  
pp. 1518-1523 ◽  
Author(s):  
James L Januzzi ◽  
Kent Lewandrowski ◽  
Thomas E MacGillivray ◽  
John B Newell ◽  
Sekar Kathiresan ◽  
...  
Keyword(s):  
Creatine Kinase ◽  
Cardiac Surgery ◽  
Cardiac Troponin ◽  
Troponin T ◽  
Cardiac Troponin T ◽  
Patient Evaluation ◽  
Creatine Kinase Mb

Cardiac troponin I, cardiac troponin T and creatine kinase MB concentrations in umbilical cord blood of healthy term neonates

2007 ◽  
Vol 92 (12) ◽  
pp. 1463-1467 ◽  
Author(s):  
D Trevisanuto ◽  
M Pitton ◽  
S Altinier ◽  
M Zaninotto ◽  
M Plebani ◽  
...  
Keyword(s):  
Creatine Kinase ◽  
Cord Blood ◽  
Umbilical Cord ◽  
Umbilical Cord Blood ◽  
Cardiac Troponin ◽  
Troponin I ◽  
Troponin T ◽  
Cardiac Troponin T ◽  
Term Neonates ◽  
Creatine Kinase Mb

Cardiac troponin T and creatine kinase MB mass concentrations in children receiving anthracycline chemotherapy

1995 ◽  
Vol 25 (3) ◽  
pp. 185-189 ◽  
Author(s):  
Franz-Martin Fink ◽  
Norbert Genser ◽  
Christoph Fink ◽  
Markus Falk ◽  
Johannes Mair ◽  
...  
Keyword(s):  
Creatine Kinase ◽  
Cardiac Troponin ◽  
Troponin T ◽  
Cardiac Troponin T ◽  
Creatine Kinase Mb ◽  
Anthracycline Chemotherapy ◽  
Mass Concentrations

scholarly journals Cardiac Troponin T and Creatine Kinase MB Content in Skeletal Muscle of the Uremic Rat

2002 ◽  
Vol 48 (6) ◽  
pp. 859-868 ◽  
Author(s):  
Salim Fredericks ◽  
Joanne F Murray ◽  
Nicholas D Carter ◽  
Alistair MS Chesser ◽  
Stavroula Papachristou ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Creatine Kinase ◽  
Cardiac Troponin ◽  
Skeletal Muscles ◽  
Troponin T ◽  
Clinical Settings ◽  
Positive Staining ◽  
Cardiac Troponin T ◽  
Creatine Kinase Mb ◽  
Trace Concentrations

Abstract Background: The assertion that creatine kinase MB (CK-MB) and the developmental isoforms of cardiac troponin T (cTnT) are expressed by skeletal muscle in some clinical settings is an extrapolation from nonuremic rodent studies. We studied the content of CK-MB and cTnT in skeletal muscle of the renal-insufficient rat. Methods: Skeletal muscles (gastrocnemius) were collected from both five-sixths nephrectomized rats (n = 11) and sham-operated controls (n = 11). cTnT content was analyzed by Elecsys (Roche), immunoblotting, and immunohistochemistry with antibodies M7 and M11-7 (Roche). CK isoenzymes were analyzed electrophoretically. Results: Trace concentrations of cTnT were detected in some of the skeletal muscle samples [controls (3 of 11) and uremic rats (1 of 11)] at concentrations <0.01% of that detected in heart. By contrast, positive staining appeared in both groups with M11-7 by immunoblotting and immunohistochemistry. No immunoreactivity was detected in skeletal muscle using M7 in the immunoblot format, although immunoreactivity was detected by immunohistochemistry in all samples. The median percentages of CK-MB were 6.0% and 4.1% for the skeletal muscle from control and uremic rats, respectively. Conclusion: The detection of cTnT and CK-MB in skeletal muscle does not differ for uremic rats compared with sham-operated controls. cTnT isoforms detected by qualitative methods are not detected with the cTnT immunoassay. Observations with rodents should not necessarily be extrapolated to humans.

Sign in / Sign up

Export Citation Format

Share Document