Apoptosis as a Possible Cause of Gradual Development of Complete Heart Block and Fatal Arrhythmias Associated With Absence of the AV Node, Sinus Node, and Internodal Pathways

Circulation ◽  
1996 ◽  
Vol 93 (7) ◽  
pp. 1424-1438 ◽  
Author(s):  
Thomas N. James ◽  
Edward St. Martin ◽  
Park W. Willis ◽  
Thomas O. Lohr
Keyword(s):  
Heart Block ◽  
Complete Heart Block ◽  
Sinus Node ◽  
Av Node ◽  
Gradual Development ◽  
Possible Cause

scholarly journals Expert’s Opinion–Challenging ECG

2020 ◽  
Vol 5 (04) ◽  
pp. 368-372
Author(s):  
Seema Kale
Keyword(s):  
Myocardial Ischaemia ◽  
Heart Block ◽  
Complete Heart Block ◽  
Conduction System ◽  
Av Block ◽  
Av Node ◽  
Purkinje System ◽  
Expert’S Opinion

AbstractVarying kinds of AV blocks can occur in the setting of myocardial ischaemia or due to degeneration of conduction system. Wenckebach AV block can present with typical Wenckebach periodicity or atypical periodicity. A variant of atypical Wenckebach periodicity may present like Mobitz II AV block. This is called Pseudo Mobitz II AV block. As we are aware that Mobitz II AV block is more dangerous and can suddenly convert into complete heart block, it is essential that we should try to differentiate between Mobitz and Pseudo Mobitz II blocks. Infact atypical Wenckebach cycles are quite common at both AV node and his Purkinje system.

scholarly journals Ventricular dyssynchrony with VVI pacemakers – Does complete heart block patients differs from sinus node dysfunction?

2015 ◽  
Vol 67 ◽  
pp. S93
Author(s):  
K. Venkatesan ◽  
M.S. Ravi ◽  
G. Palanisamy ◽  
N. Swaminathan ◽  
G. Ravishankar ◽  
...  
Keyword(s):  
Heart Block ◽  
Complete Heart Block ◽  
Sinus Node ◽  
Sinus Node Dysfunction ◽  
Ventricular Dyssynchrony

Persistent Fetal Sinus Bradycardia Associated with Maternal Anti-SSA/Ro and Anti-SSB/La Antibodies

2011 ◽  
Vol 38 (12) ◽  
pp. 2682-2685 ◽  
Author(s):  
PRIYA CHOCKALINGAM ◽  
EDGAR T. JAEGGI ◽  
LUKAS A. RAMMELOO ◽  
MONIQUE C. HAAK ◽  
PHEBE N. ADAMA van SCHELTEMA ◽  
...  
Keyword(s):  
Heart Block ◽  
Cardiac Involvement ◽  
Clinical Course ◽  
Complete Heart Block ◽  
Sinus Bradycardia ◽  
Sinus Node ◽  
Good Prognosis ◽  
Sinus Arrest ◽  
Congenital Complete Heart Block ◽  
Myocardial Involvement

Objective.To study the clinical course and outcome of fetal sinus bradycardia (SB) due to maternal antibody-induced sinus node dysfunction.Methods.We reviewed the maternal, prenatal, and postnatal findings of fetuses with SB associated with elevated maternal anti-SSA/Ro and anti-SSB/La antibodies.Results.Of the 6 cases diagnosed prenatally, 3 had isolated SB persisting after birth and had a good prognosis. Three fetuses with SB and severe myocardial involvement (congenital complete heart block and/or endocardial fibroelastosis) succumbed in utero in spite of treatment. Postmortem histopathology in 1 fetus showed inflammatory destruction of the sinus and atrioventricular nodes. SB was detected incidentally in a 7-year-old girl. She had intermittent heart block with progressive sinus arrest requiring permanent pacemaker.Conclusion.Fetal SB associated with maternal autoantibodies may persist in childhood, with a good prognosis in the absence of widespread cardiac involvement.

Chronotropic competence of the sinus node in congenital complete heart block

1998 ◽  
Vol 82 (9) ◽  
pp. 1119-1121 ◽  
Author(s):  
Anil Menon ◽  
Earl Dean Silverman ◽  
Robert Malcolm Gow ◽  
Robert Murray Hamilton
Keyword(s):  
Heart Block ◽  
Complete Heart Block ◽  
Sinus Node ◽  
Congenital Complete Heart Block

Complete heart block in a patient with acute lymphoblastic leukaemia: teicoplanin as a possible cause and review of literature

2012 ◽  
Vol 38 (2) ◽  
pp. 156-158 ◽  
Author(s):  
A. Sharif-Yakan ◽  
M. Arabi ◽  
U. M. Musharrafieh ◽  
F. F. Bitar ◽  
R. Saab ◽  
...  
Keyword(s):  
Acute Lymphoblastic Leukaemia ◽  
Lymphoblastic Leukaemia ◽  
Heart Block ◽  
Complete Heart Block ◽  
Review Of Literature ◽  
Possible Cause

Mobitz Type II Atrioventricular Block in a Newborn

PEDIATRICS ◽  
1972 ◽  
Vol 50 (2) ◽  
pp. 333-336
Author(s):  
David T. Kelly ◽  
Richard D. Rowe
Keyword(s):  
Heart Block ◽  
Complete Heart Block ◽  
Type Ii ◽  
Av Block ◽  
Ventricular Pacing ◽  
Qrs Complex ◽  
Av Node ◽  
Cardiac Lesion ◽  
Congenital Complete Heart Block ◽  
Mobitz Type

Patients with congenital complete heart block and no other cardiac lesion usually are asvmptomatic and have a normal axis and QRS pattern on the electrocardiogram. The site of the block is usually in the region of the AV node. Another less common type of congenital AV block has an abnormal QRS complex on the electrocardiogram. Death from Stokes-Adams attack has been recorded in infancy in this group. Mobitz Type II block is very rare in infancy but may precede complete heart block which requires ventricular pacing. The purpose of this report is to illustrate Mobitz Type II heart block in a newborn which progressed to complete block.

How many patients treated for bradycardia may be eligible for His bundle pacing?

EP Europace ◽  
2021 ◽  
Vol 23 (Supplement_3) ◽  
Author(s):  
R Chattopadhyay ◽  
P Chousou ◽  
R Thomas ◽  
J O"brien ◽  
F Pierres ◽  
...  
Keyword(s):  
Heart Block ◽  
Sinus Node ◽  
Conduction System ◽  
Ventricular Pacing ◽  
Av Node ◽  
His Bundle ◽  
His Bundle Pacing ◽  
Funding Sources ◽  
System Disease ◽  
Class Iib

Abstract Funding Acknowledgements Type of funding sources: None. Introduction Pacing-Induced Cardiomyopathy (PICM) can lead to significant morbidity, requiring treatment by device upgrade procedures. The risk of occurrence is directly related to the burden of right ventricular pacing, which can be reduced by careful device programming. When frequent ventricular stimulation cannot be avoided, pacing the conduction system may offer an alternative to myocardial pacing and reduce the risk of PICM. The most recent international pacing guidelines recommend that His-bundle pacing should be considered among 1) patients with EF 36-50% and expected to require >40% ventricular pacing (Vp > 40%) (class IIa); and 2) patients requiring pacing who have block at the level of the AV node (class IIb). Purpose This study sought to determine how many patients undergoing bradycardia pacing would have fulfilled those criteria. Methods This was a single-centre retrospective study over a 5 year period to the end of April 2020. Demographic and clinical details of patients receiving device implants were obtained from the Pacing Service Database, along with the indication for pacing, electrocardiographic and echocardiographic data. A cardiology consultant with a special interest in pacing reviewed each case with regards to the likelihood of requiring >40% ventricular pacing. Heart block at the level of the AV node was considered present if patients presented with a narrow QRS in conjunction with second or third degree heart block. Results 1,265 patients underwent pacemaker implant for bradycardia during the study period, 888 for conduction system disease (198 second degree block, 333 complete heart block), 349 for sinus node disease and 28 for other indication. Figure 1 gives a breakdown of patients with conduction system block according to i) level of block; ii) ejection fraction; iii) expectation or not of Vp > 40%.  In total, 166 patients had a class IIa indication for His-bundle pacing. 227 patients had block at the level of the AV node, of whom 36 also fulfilled the class IIa criteria for His-bundle pacing; 191 patients (16% of the total) had a sole class IIb indication for His-bundle pacing. Adjusting for the 176 patients who did not undergo echocardiography, up to an additional 45 patients may be expected to have an indication for His-bundle pacing Conclusion As many as 32% of patients in a bradycardia pacing population may be eligible for His-bundle pacing. This has significant implications for training and service provision. Abstract Figure 1. Flowsheet showing distribution

Congenital Complete Heart Block

2007 ◽  
Vol 3 (2) ◽  
pp. 111
Author(s):  
Robert Campbell ◽  
Peter Fischbach ◽  
Patricio Frias ◽  
Margaret Strieper ◽  
◽  
...  
Keyword(s):  
Heart Block ◽  
Complete Heart Block ◽  
Congenital Complete Heart Block
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