scholarly journals Use of Krypton 85 for the Measurement of Cardiac Output by the Single-Injection Indicator-Dilution Technique

1961 ◽  
Vol 9 (5) ◽  
pp. 984-988 ◽  
Author(s):  
WILLIAM P. CORNELL ◽  
EUGENE BRAUNWALD ◽  
EDWIN C. BROCKENBROUGH
1962 ◽  
Vol 11 (4) ◽  
pp. 712-720 ◽  
Author(s):  
Julian C. Sleeper ◽  
Howard K. Thompson ◽  
Henry D. McIntosh ◽  
Robert C. Elston

1959 ◽  
Vol 196 (4) ◽  
pp. 751-752 ◽  
Author(s):  
Leo A. Sapirstein ◽  
Frank A. Hartman

The cardiac output of the chicken has been measured by the indicator dilution technique and its distribution determined by the indicator distribution technique. The cardiac output is 218 ml/kg/min. The coronary flow fraction is 4.9% of the cardiac output, the renal flow fraction, 15.2% of the cardiac output, and the splanchnic flow fraction, 17.4% of the cardiac output. The perfusion rates of the thyroid and adrenal glands are similar to those found in the rat.


1977 ◽  
Vol 233 (3) ◽  
pp. H350-H355
Author(s):  
L. D. Homer ◽  
A. Small

A model incorporating the effects of recirculation time lag, cardiac output, clearance, volume of distribution, and the variance of the distribution of recirculation times is applied to the analysis of indicator dilution curves. Experiments on dogs with use of radioactively labeled diethylenetriaminepentaacetic acid were done to evaluate the model. This five-parameter model can be fitted to data obtained during the period from less than 1 min to 3 h after a single injection of indicator. Estimates of cardiac output and clearance are in satisfactory agreement with estimates obtained by alternative techniques. Estimates of the time lag and volume of distribution are of physiologically plausible magnitude. The variance of the distribution of recirculation times is a new parameter, of which the possible usefulness to physiologists is discussed.


1990 ◽  
Vol 67 (4) ◽  
pp. 902-912 ◽  
Author(s):  
J H Revkin ◽  
L H Young ◽  
W S Stirewalt ◽  
D M Dahl ◽  
R A Gelfand ◽  
...  

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