Abstract 2490: Non-uniformity of Three-dimensional Left Ventricular Relaxation Abnormalities in Hypertensive Left Ventricular Hypertrophy by Speckle Tracking Global Strain Rate Imaging

Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
Takeshi Takamura ◽  
Kaoru Dohi ◽  
Katsuya Onishi ◽  
Naoki Fujimoto ◽  
Tairo Kurita ◽  
...  
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Strain Rate ◽  
Speckle Tracking ◽  
Ventricular Hypertrophy ◽  
Systolic Function ◽  
Left Ventricular ◽  
Strain Rate Imaging ◽  
Global Strain ◽  
Lv Systolic Function ◽  
Global Strain Rate

Background: We tested the hypothesis that global strain rate imaging can quantify and stratify the severity of left ventricular (LV) relaxation abnormality in patients with left ventricular hypertrophy (LVH) ranged from normal to reduced LV systolic function independently from longitudinal (L), circumferential (C), and radial axes (R). Methods: Fifty-seven patients with hypertensive LVH and thirty age matched controls (Control, EF 65 ± 5 %) had echo-study with speckle tracking strain and strain rate imaging from (L), (C), and (R). LVH were divided into two groups; normal EF (LVH-NEF) defined as EF ≥ 55% (n = 35, EF 64 = 5 %), and systolic dysfunction (LVH-SD) defined as EF < 55% (n = 22, EF 48 ± 8 %). Global peak systolic strain (PSS) and peak relaxation rate (PRR) were used as indices of global LV contraction and relaxation, respectively (Vivid 7 and EchoPAC, GE Electronic). Results: PSS was maintained in LVH-NEF but reduced in LVH-SD from all three perpendicular axes. PRR (L) was impaired in LVH-NEF and was further decreased in LVH-SD (0.95 ± 0.33* and 0.58 ± 0.24* † 1/s, *p <0.05 vs. Control and † p <0.05 vs. LVH-NEF, respectively)compared to Control (1.14 ± 0.30 1/s). PRR (C) was maintained in LVH-NEF but reduced in LVH-SD (1.24 ± 0.50 and 0.73 ± 0.36 1/s*, p <0.05 vs. Control) compared to Control (1.30 ± 0.48 1/s). PRR (R) was impaired in both LVH-NEF and LVH-SD in the same degrees (-1.53 ± 0.60* and -1.27 ± 0.64* 1/s, p <0.05 vs. Control: -2.08 ± 0.84 1/s). Conclusion: Speckle tracking strain rate imaging quantified and stratified the severity of LV relaxation abnormality in patients with LVH ranged from normal to reduced LV systolic function independently from all three perpendicular ventricular axes.

scholarly journals Transplantation of cardiac allografts with left ventricular hypertrophy 1.5 cm and more

2019 ◽  
Vol 21 (1) ◽  
pp. 7-16 ◽  
Author(s):  
V. N. Poptsov ◽  
E. A. Spirina ◽  
S. Yu. Ustin ◽  
S. A. Masutin ◽  
A. A. Dogonacheva ◽  
...  
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Ventricular Hypertrophy ◽  
Systolic Function ◽  
Early Period ◽  
Left Ventricular ◽  
Donor Heart ◽  
Term Survival ◽  
Cardiac Allografts ◽  
Lv Systolic Function

Introduction. In case of donor heart shortage and expanding pool of patients waiting for heart transplantation (OHTx) liberalization of donor selection, especially use of donors with left ventricular hypertrophy (LVH), may be one of most realistic methods to extending number of OHTx.Aim: to evaluate early and late outcomes after OHTx from donors with LVH ≥1.5 cm.Methods. We reviewed 160 heart recipients who underwent OHTx from donors with LVH 1.5 cm or more from 2011 to 2017.Results. The duration of anesthesia was 6.5 ± 0.7 h, surgery – 4.7 ± 0.3 h, cardiopulmonary bypass – 63–290 (145 ± 47) min and ischemia time was – 86–426 (168 ± 44) min. ICU stay was 7.4 ± 8.5 days. Hospital mortality in the study group was 8,1% (n = 13) and 30-day survival was 91.9%. Patients with or without donor LVH had similar early and long-term survival (p = 0.659).Conclusions. Own experience demonstrates the satisfactory results of HT from donors with LVH. In more cases, LV systolic function of cardiac allograft quickly normalized in the early period after HT.

scholarly journals Value of quantitative analysis of left ventricular systolic function in patients on maintenance hemodialysis based on myocardial work technique

2021 ◽  
Author(s):  
Chang Liu ◽  
Yi-Ping Feng ◽  
Zi-Ning Yan ◽  
Li Fan ◽  
Yi-Fei Rui ◽  
...  
Keyword(s):  
Quantitative Analysis ◽  
Left Ventricular Hypertrophy ◽  
Receiver Operating Characteristic ◽  
Ventricular Hypertrophy ◽  
Operating Characteristic ◽  
Systolic Function ◽  
Left Ventricular ◽  
Maintenance Hemodialysis ◽  
Global Work ◽  
Lv Systolic Function

Abstract Background: This study aimed to determine the left ventricular (LV) systolic function in patients on maintenance hemodialysis (MHD) using the myocardial work (MW) technique and investigate the clinical value of the MW technique for the quantitative analysis of left ventricular (LV) systolic function in MHD patients with left ventricular hypertrophy (LVH).Methods: A total of 68 MHD patients and 35 controls were registered in this study. The MHD patients were divided into the non-left ventricular hypertrophy (NLVH) group (n=35) and the LVH group (n=33) according to the LV mass index (LVMI). MW was used to generate the LV global longitudinal strain (GLS), global work index (GWI), global constructive work (GCW), and global wasted work (GWW), global work efficiency (GWE). GLS and the MW parameters (GWI, GCW, GWW, GWE) were compared between groups and the correlations between these parameters and the LV ejection fraction (LVEF) in the LVH group were examined. The receiver operating characteristic (ROC) curve was used to evaluate the efficacy of MW parameters and GLS for the assessment of LV systolic dysfunction in MHD with LVH patients.Results: The LVH group had significantly lower GWE, GWI, GCW, and GLS but higher GWW than the control and NLVH groups. Compared with the control group, the NLVH group had significantly lower GWE and GLS and higher GWW, but no significant differences in GWI, GCW were observed between these two groups. The LVEF was negatively correlated with GWW in MHD patients, but positively correlated with GWI, GWE, and GCW in the LVH group. Receiver operating characteristic curve (ROC) analysis revealed that GWE, GWW, GWI, and GCW had appreciable area under the curve (AUC), sensitivity, and specificity for evaluating LV function in LVH patients on MHD. Conclusion: The MW parameters can quantitatively represent the LV myocardial work in MHD patients. Thus, the technique provides a new method for the quantitative evaluation of LV systolic function in MHD with LVH patients.

scholarly journals Value of quantitative analysis of left ventricular systolic function in patients on maintenance hemodialysis based on myocardial work technique

2020 ◽  
Author(s):  
Chang Liu ◽  
Yi-Ping Feng ◽  
Zi-Ning Yan ◽  
Li Fan ◽  
Yi-Fei Rui ◽  
...  
Keyword(s):  
Quantitative Analysis ◽  
Left Ventricular Hypertrophy ◽  
Receiver Operating Characteristic ◽  
Ventricular Hypertrophy ◽  
Operating Characteristic ◽  
Systolic Function ◽  
Left Ventricular ◽  
Maintenance Hemodialysis ◽  
Global Work ◽  
Lv Systolic Function

Abstract Background: To detect the left ventricular (LV) systolic function in maintenance hemodialysis (MHD) patients by using myocardial work (MW) technique. And investigated the clinical value of the MW technique for the quantitative analysis of left ventricular (LV) systolic function in MHD patients with left ventricular hypertrophy (LVH).Methods: A total of 58 MHD patients and 29 normal subjects were registered in this study. The MHD patients were divided into the non-left ventricular hypertrophy (NLVH) group (n=32) and the LVH group (n=26) according to the LV myocardial index (LVMI). MW was used to generated the LV global longitudinal strain (GLS), global work index (GWI), global constructive work (GCW), global wasted work (GWW), global work efficiency (GWE. GLS and the MW parameters (GWI, GCW, GWW, GWE) were compared between groups and the correlations between these parameters and the LV ejection fraction (LVEF) in the LVH group were examined. The receiver operating characteristic (ROC) curve was used to evaluate the efficacy of MW parameters and GLS for the assessment of LV systolic dysfunction in MHD patients with LVH.Results: The LVH group had significantly lower GWE, GWI, GCW, and GLS but higher GWW than the control and NLVH groups. Compared with the control group, the NLVH group had significantly lower GWE and GLS and higher GWW, but no significant differences in GWI, GCW were observed between these two groups. The LVEF was negatively correlated with GWW in MHD patients, but positively correlated with GWI, GWE, and GCW in the LVH group. Receiver operating characteristic curve (ROC) analysis revealed that GWE, GWW, GWI, and GCW had appreciable area under the curve (AUC), sensitivity, and specificity for evaluating LV function in LVH patients. Conclusion: MW parameters can be effectively used to evaluate the LV systolic function in MHD patients with or without LVH.

Abstract 2431: Global Strain with Speckle Tracking Method is Next Generation Index of Left Ventricular Systolic Function

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Hideaki Kanzaki ◽  
Makoto Amaki ◽  
Takuya Hasegawa ◽  
Takahiro Ohara ◽  
Kazuhiko Hashimura ◽  
...  
Keyword(s):  
Speckle Tracking ◽  
Systolic Function ◽  
Myocardial Strain ◽  
Left Ventricular ◽  
Peak Strain ◽  
Anterior Myocardial Infarction ◽  
Endocardial Border ◽  
Global Strain ◽  
Lv Systolic Function ◽  
Bull's Eye

Background. Myocardial strain is an index of regional function, whereas global left ventricular (LV) systolic function is generally assessed with ejection fraction (EF). Recent development of speckle tracking analysis software allows angle-independent and less time-consuming measurement of whole LV strain. Our objective was to assess whether the method is useful as another index of global LV systolic function. Methods. In 54 patients (LVEF 36±19%, 7–72%), digital gray-scales cine-loops were acquired from the apical 4-, 2-chamber, and long-axis views (GE Vivid7). After defining a region of interest (ROI) by tracing the LV endocardial border with several points at each view, a bull’s eye map was automatically constructed based on longitudinal strain and an averaged value of systolic peak strain was easily determined (EchoPAC Dimension AFI, GE). The strain value multiplied by −1 was used as global strain. Nineteen of the 54 patients underwent dobutamine stress and global strain value was calculated at baseline and during administration of 10 μg/kg/min. Results. Figure at left shows a bull’s eye strain map in a case of anterior myocardial infarction with regional dyskinetic wall motion. The blue area indicates the dyskinetic region. Despite of low dose, dobutamine increased global strain value (from 15.3 ± 5.3 to 17.1 ± 6.0, P <0.001) as well as LVEF. Figure at right shows global strain value was well correlated with LVEF ( r =0.917, P <0.001). Conclusion. Global strain is a new index which reflects the location, severity and extent of myocardial damage in addition to global LV systolic function.

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