Abstract 111: In-hospital Cardiac Arrest: Predictors Of Long Term Survival After Being Discharged Alive

Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
Wessel Keuper ◽  
Hendrik-Jan Dieker ◽  
Marc A Brouwer ◽  
Freek W Verheugt

Background Long term survival of patients discharged alive after cardiopulmonary resuscitation (CPR) for an in-hospital cardiac arrest (IHCA) has not been extensively studied. It is also largely unknown which of these patients are at high risk for poor survival. Therefore we studied survival and predictors of survival for these patients. Methods We retrospectively studied patients who suffered from an IHCA between 1997–2004 and who survived to discharge. Data were collected using an Utstein form. A Kaplan Meier curve was calculated for survival. Survivors were compared with non-survivors and Cox regression analysis was performed to determine predictors of survival. Results In this period 222 patients had an IHCA and 19% (n=42) was discharged alive. Known predictors of survival to discharge were confirmed, primarily initial rhythm. In the discharged patients, survival after a median follow-up of 2.9 years (IQR 1.5–7.2) was 57% (n=24). Non-survivors were significantly older, median age 69.3 (IQR 59.6 –75.2) versus 56.7 (IQR 48.1– 68.8) years and had significantly more often diabetes mellitus, arrhythmias, valvular disease and cancer in their medical history than survivors. Initial rhythm did not differ between groups. After adjustment for baseline differences it was found that cancer independently predicted a lower chance of survival (HR 2.8; 95% CI 1.1–7.5). Older age tended to predict a lower chance of survival as well. Conclusion Whenever a patient is discharged alive after an IHCA, the chance of survival is evidently reduced. Only cancer independently predicted a lower chance of survival. Long term survival seems to be determined more by comorbidity than arrest variables.

Resuscitation ◽  
2007 ◽  
Vol 75 (1) ◽  
pp. 23-28 ◽  
Author(s):  
Nana G. Holler ◽  
Teit Mantoni ◽  
Søren L. Nielsen ◽  
Freddy Lippert ◽  
Lars S. Rasmussen

Resuscitation ◽  
2021 ◽  
Vol 164 ◽  
pp. 30-37
Author(s):  
Richard Chocron ◽  
Carol Fahrenbruch ◽  
Lihua Yin ◽  
Sally Guan ◽  
Christopher Drucker ◽  
...  

2014 ◽  
Vol 3 (4) ◽  
pp. 293-303 ◽  
Author(s):  
Per Nordberg ◽  
Jacob Hollenberg ◽  
Mårten Rosenqvist ◽  
Johan Herlitz ◽  
Martin Jonsson ◽  
...  

2020 ◽  
Vol 13 (1) ◽  
pp. 25-29 ◽  
Author(s):  
Iisa Lindström ◽  
Sara Protto ◽  
Niina Khan ◽  
Jussi Hernesniemi ◽  
Niko Sillanpää ◽  
...  

BackgroundMasseter area (MA), a surrogate for sarcopenia, appears to be useful when estimating postoperative survival, but there is lack of consensus regarding the potential predictive value of sarcopenia in acute ischemic stroke (AIS) patients. We hypothesized that MA and density (MD) evaluated from pre-interventional CT angiography scans predict postinterventional survival in patients undergoing mechanical thrombectomy (MT).Materials and methods312 patients treated with MT for acute occlusions of the internal carotid artery (ICA) or the M1 segment of the middle cerebral artery (M1-MCA) between 2013 and 2018. Median follow-up was 27.4 months (range 0–70.4). Binary logistic (alive at 3 months, OR <1) and Cox regression analyses were used to study the effect of MA and MD averages (MAavg and MDavg) on survival.ResultsIn Kaplan–Meier analysis, there was a significant inverse relationship with both MDavg and MAavg and mortality (MDavg P<0.001, MAavg P=0.002). Long-term mortality was 19.6% (n=61) and 3-month mortality 12.2% (n=38). In multivariable logistic regression analysis at 3 months, per 1-SD increase MDavg (OR 0.61, 95% CI 0.41 to 0.92, P=0.018:) and MAavg (OR 0.57, 95% CI 0.35 to 0.91, P=0.019) were the independent predictors associated with lower mortality. In Cox regression analysis, MDavg and MAavg were not associated with long-term survival.ConclusionsIn acute ischemic stroke patients, MDavg and MAavg are independent predictors of 3-month survival after MT of the ICA or M1-MCA. A 1-SD increase in MDavg and MAavg was associated with a 39%–43% decrease in the probability of death during the first 3 months after MT.


Resuscitation ◽  
2020 ◽  
Vol 157 ◽  
pp. 108-111
Author(s):  
David Majewski ◽  
Stephen Ball ◽  
Paul Bailey ◽  
Janet Bray ◽  
Judith Finn

Resuscitation ◽  
2016 ◽  
Vol 106 ◽  
pp. e23-e24
Author(s):  
Simone Savastano ◽  
Gianmarco Iannopollo ◽  
Marco Ferlini ◽  
Gabriele Crimi ◽  
Alessandra Repetto ◽  
...  

Resuscitation ◽  
2018 ◽  
Vol 130 ◽  
pp. e108
Author(s):  
Sidsel Møller ◽  
Fredrik Folke ◽  
Carolina Malta Hansen ◽  
Steen Møller Hansen ◽  
Freddy Lippert ◽  
...  

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Guang-Chuan Mu ◽  
Yuan Huang ◽  
Zhi-Ming Liu ◽  
Xiang-Hua Wu ◽  
Xin-Gan Qin ◽  
...  

Abstract Background The aim of this study was to explore the prognostic factors and establish a nomogram to predict the long-term survival of gastric cancer patients. Methods The clinicopathological data of 421 gastric cancer patients, who were treated with radical D2 lymphadenectomy by the same surgical team between January 2009 and March 2017, were collected. The analysis of long-term survival was performed using Cox regression analysis. Based on the multivariate analysis results, a prognostic nomogram was formulated to predict the 5-year survival rate probability. Results In the present study, the total overall 3-year and 5-year survival rates were 58.7 and 45.8%, respectively. The results of the univariate Cox regression analysis revealed that tumor staging, tumor location, Borrmann type, the number of lymph nodes dissected, the number of lymph node metastases, positive lymph nodes ratio, lymphocyte count, serum albumin, CEA, CA153, CA199, BMI, tumor size, nerve invasion, and vascular invasion were prognostic factors for gastric cancer (all, P < 0.05). However, merely tumor staging, tumor location, positive lymph node ratio, CA199, BMI, tumor size, nerve invasion, and vascular invasion were independent risk factors, based on the results of the multivariate Cox regression analysis (all, P < 0.05). The nomogram based on eight independent prognostic factors revealed a well-degree of differentiation with a concordance index of 0.76 (95% CI: 0.72–0.79, P < 0.001), which was better than the AJCC-7 staging system (concordance index = 0.68). Conclusion The present study established a nomogram based on eight independent prognostic factors to predict long-term survival in gastric cancer patients. The nomogram would be beneficial for more accurately predicting the prognosis of gastric cancer, and provide important basis for making individualized treatment plans following surgery.


Author(s):  
Xiaoying Lou ◽  
Andrew Sanders ◽  
Kaustubh Wagh ◽  
Jose N. Binongo ◽  
Manu Sancheti ◽  
...  

Objective Octogenarians comprise an increasing proportion of patients presenting with non-small-cell lung cancer (NSCLC). This study examines postoperative morbidity and mortality, and long-term survival in octogenarians undergoing thoracoscopic anatomic lung resection for NSCLC, compared with younger cohorts. Methods We conducted a retrospective review of our institutional Society of Thoracic Surgeons General Thoracic Surgery Database of all patients ≥60 years old undergoing elective lobectomy or segmentectomy for pathologic stage I, II, and IIIA NSCLC between 2009 and 2018. Results were compared between octogenarians ( n = 71) to 2 younger cohorts of 60- to 69-year-olds ( n = 359) and 70- to 79-year-olds ( n = 308). Long-term survival among octogenarians was graphically summarized using the Kaplan–Meier method. Cox regression analysis was used to identify preoperative risk factors for mortality. Results A greater proportion of octogenarians required intensive care unit admission and discharge to extended-care facilities; however, postoperative length of stay was similar between groups. Among postoperative complications, arrhythmia and renal failure were more likely in the older cohort. Compared to the youngest cohort, in-hospital and 30-day mortality were highest among octogenarians. Overall survival among octogenarians at 1, 3, and 5 years was 87.3%, 61.8%, and 50.5%, respectively. On multivariable Cox regression analysis of baseline demographic variables, presence of stroke (hazard ratio [HR] = 28.5, 95% confidence interval [CI]: 6.1 to 132.7, P < 0.001) and coronary artery disease (HR = 2.5, 95% CI: 1.2 to 5.3, P = 0.02) were significant predictors of overall mortality among octogenarians. Conclusions Thoracoscopic resection can be performed with favorable early postoperative outcomes among octogenarians. Long-term survival, although comparable to their healthy peers, is worse than those of younger cohorts. Further study into preoperative risk stratification and alternative therapies among octogenarians is needed.


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