scholarly journals Multicenter Evaluation of Dynamic Three-Dimensional Magnetic Resonance Myocardial Perfusion Imaging for the Detection of Coronary Artery Disease Defined by Fractional Flow Reserve

Author(s):  
Robert Manka ◽  
Lukas Wissmann ◽  
Rolf Gebker ◽  
Roy Jogiya ◽  
Manish Motwani ◽  
...  
2021 ◽  
Vol 8 ◽  
Author(s):  
Russell Franks ◽  
Sven Plein ◽  
Amedeo Chiribiri

Functionally significant coronary artery disease impairs myocardial blood flow and can be detected non-invasively by myocardial perfusion imaging. While multiple myocardial perfusion imaging modalities exist, the high spatial and temporal resolution of cardiovascular magnetic resonance (CMR), combined with its freedom from ionising radiation make it an attractive option. Dynamic contrast enhanced CMR perfusion imaging has become a well-validated non-invasive tool for the assessment and risk stratification of patients with coronary artery disease and is recommended by international guidelines. This article presents an overview of CMR perfusion imaging and its clinical application, with a focus on chronic coronary syndromes, highlighting its strengths and challenges, and discusses recent advances, including the emerging role of quantitative perfusion analysis.


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