Somatostatin Receptor Positron Emission Tomography/Computed Tomography in Giant Cell Myocarditis: A Promising Approach to Molecular Myocardial Inflammation Imaging

Author(s):  
Christian L. Polte ◽  
Entela Bollano ◽  
Anders Oldfors ◽  
Anna Dudás ◽  
Kerstin M. Lagerstrand ◽  
...  
2013 ◽  
Vol 98 (11) ◽  
pp. 4262-4266 ◽  
Author(s):  
Justin Michel ◽  
David Taïeb ◽  
Marianne Jolibert ◽  
Julia Torrents ◽  
Michel Wassef ◽  
...  

Context: Sinonasal paragangliomas have rarely been reported in the literature. They are often aggressive. Patient: We report an original case of sinonasal paragangliomas with a tumor recurrence diagnosed 13 years after resection of the primary tumor. Somatostatin receptor scintigraphy and [18F]-fluorodeoxyglucose positron emission tomography/computed tomography were the most sensitive functional imaging techniques, and they ruled out distant metastases. Interestingly, [18F]-fluorodihydroxyphenylalanine positron emission tomography/computed tomography was negative, a feature that may be considered a sign of functional dedifferentiation. Screening for germline mutations of the SDHB, SDHC, SDHD, SDHAF2, VHL, MAX, and TMEM127 was negative. Conclusion: The diagnosis of malignancy remains challenging at initial diagnosis, and patients should be followed during their entire lifetime.


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