Abstract 22: Outcome Of Patients With Basilar Artery Bifurcation Aneurysm Who Underwent With Endovascular Approach

Author(s):  
Yahia M Lodi ◽  
Khalid Sethi ◽  
Dan Gaylon ◽  
Syed Bajwa

Background: Due to a high surgical risk, endovascular repair of the basilar artery (BA) aneurysm is considered the primary option for most of the cases. However, procedure related complications, clinical outcome and rate of recurrence in BA bifurcation aneurysms are not specifically addressed. Objectives: is to describe the incidence of endovascular procedure related complications, recurrence of aneurysm and long-term clinical outcome of BA aneurysm. Methods: Consecutive patients who underwent endovascular repair of BA bifurcation aneurysm were enrolled from 2007 to 2010. Patient’s demographics including the Hunt & Hess (H&H) grade, Fished scale, and size of aneurysm were collected. Complications including aneurysm rupture, intracranial hemorrhage or thromboembolic event were recorded. Additionally, 90-days outcome measurement was obtained using Glasgow Outcome Scale (GOS). Results: 36 patients with a mean age of 50 plus-minus 14 years required 48 successful procedures to treat 36 BA bifurcation aneurysms. Ruptured aneurysm was present in 20 cases (H&H I in 6, II in 4, III in 4 and IV in 6). 30 patients (83%) had wide neck aneurysm, 25 (69%) of which required stent in order to secure the aneurysm. There was no intraoperative rupture of aneurysm or thromboembolic event. However, one patient developed diplopia with visual incoordination on day one and other developed diplopia due to a small pontine stroke while stopping clopidogrel on post operative day 30 of stent-assisted repair. Both patients recovered completely with no disability. Ten patients (28%) had recurrence of aneurysm and required subsequent procedure. In recurrent aneurysms, repeat procedures had no negative impact on the clinical outcome. One patient died (GOS 1) who initially presented with H&H IV and never recovered. Good outcome was observed in 32 (89%) patients (GOS 5 in 31, GOS 4 in 1) including all unruptured cases and 3 of 5 ruptured BA aneurysm patients who presented with H&H of IV. Poor outcome was observed in 3 (8%) patients (GOS 3 in 3, 2 of which presented with H&H IV). Conclusion: Endovascular repair of the BA bifurcation aneurysms are associated with good clinical outcome despite requirement of multiple procedures to complete the treatment. However, the recurrence of aneurysm is very high. Therefore, a very close angiographic follow-up is necessary.

2005 ◽  
Vol 103 (6) ◽  
pp. 990-999 ◽  
Author(s):  
Hans Henkes ◽  
Sebastian Fischer ◽  
Wagner Mariushi ◽  
Werner Weber ◽  
Thomas Liebig ◽  
...  

Object. The aim of this study was to analyze the effect of the endovascular treatment of basilar artery (BA) bifurcation aneurysms and to compare the results with those published by other neuroendovascular teams. Methods. The authors performed a retrospective analysis of 316 aneurysms of the BA bifurcation that had been treated using endovascular coil occlusion between November 6, 1992, and February 12, 2005. After the initial embolization procedure, a 90 to 100% occlusion rate was achieved in 86% of the aneurysms. No complication was evident in 80% of the lesions, although periprocedural aneurysm rupture (3.2%) and thromboembolic events (12.3%) were the most frequent complications. Clinical outcome according to the Glasgow Outcome Scale (GOS) was a score of 5 or 4 in 77%, 3 in 11%, 2 in 5%, and 1 in 7% of patients. Initial follow-up angiography studies were obtained in 56% of patients at a mean of 19 months posttreatment and demonstrated a 90 to 100% occlusion rate in 70%. No recurrence was seen on 65% of the aneurysms. Coil compaction was evident on 24% of the follow-up angiograms. A second treatment was performed on 48 aneurysms (15%) a mean of 27 months after the first therapeutic session and resulted in 90 to 100% occlusion in 83% of the lesions. Complications were encountered in 19% of the aneurysms. Rupture did not occur during any of the procedures. Clinical outcome was rated as GOS Score 5 or 4 in 83% of the patients and Grade 3 in 17%. During a cumulative clinical follow up of 821 years in 237 patients, 182 patients (81%) were independent (GOS Score 5 or 4), 33 (14%) were dependent (GOS Score 3), eight (3%) were in a vegetative state, and two (1%) had died. Clinical outcome was significantly worse after previous aneurysm rupture and following procedural complications. Conclusions. These results are within the range of published data for coil treatment of BA tip aneurysms and confirm both the safety and efficacy of this endovascular treatment method.


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