scholarly journals Renin Gene Polymorphisms and Haplotypes, Blood Pressure, and Responses to Renin-Angiotensin System Inhibition

Hypertension ◽  
2007 ◽  
Vol 50 (2) ◽  
pp. 340-347 ◽  
Author(s):  
Niamh Moore ◽  
Patrick Dicker ◽  
John K. O’Brien ◽  
Milos Stojanovic ◽  
Ronán M. Conroy ◽  
...  
1992 ◽  
Vol 4 (2) ◽  
pp. 59-71 ◽  
Author(s):  
F Broughton Pipkin

Given the phylogenic antiquity of the renin angiotensin system (RAS) and the high degree of renin gene sequence conservation between species, it is perhaps not surprising that the RAS should be central to cardiovascular homeostasis. Nor, given the common embryological origin of the kidneys and reproductive tracts, is it especially surprising that the system should be influenced by, and may itself influence, the state of pregnancy. In this review I shall attempt to give an outline of the workings of the system in normal and in hypertensive pregnancy. The RAS is now known to be involved in spheres far beyond the ‘simple’ control of sodium and water homeostasis, and hence of blood pressure. Its roles in reproduction and in fetal life in animals have been very recently reviewed; this review will therefore confine itself to human studies unless otherwise stated.


2017 ◽  
Vol 18 (1) ◽  
Author(s):  
Sandrita Simonyte ◽  
Renata Kuciene ◽  
Jurate Medzioniene ◽  
Virginija Dulskiene ◽  
Vaiva Lesauskaite

Sign in / Sign up

Export Citation Format

Share Document