Abstract TP333: The Volume of an Acute Intracerebral Hemorrhage May Be Larger Than it Appears on Computed Tomography Scan

Stroke ◽  
2020 ◽  
Vol 51 (Suppl_1) ◽  
Author(s):  
Takahiro Sato

Background and Purpose: Computed tomography (CT) scan is difficult to detect early-onset acute intracerebral hemorrhage (ICH) rich in fresh blood correctly. We identified the presence of a perihematomal low-density lesion on CT imaging, which showed a high-intensity signal on T2-weighted imaging and an iso-intensity signal on fluid-attenuated inversion recovery imaging in magnetic resonance imaging (MRI) (Figure. A~C). It located inside of the hypo-intensity rim at the edge of hematoma on gradient recalled echo T2*-weighted imaging (Figure. D). We named it the “CT wall sign” and investigated the association with imaging findings in acute ICH. Methods: Patients with acute ICH within 24 hours from onset who underwent non-contrast head CT and MRI scan at the same time periods were included. The ICH volumes on CT and MRI (cm 3 ) were measured using a three-dimensional slicer and compared. Subjects were divided according to the presence or absence of the CT wall sign and compared the neuroradiological variables. Statistical analyses were performed to evaluate the association between the CT wall sign and other imaging findings. Results: A total of 146 patients were included and the CT wall sign was observed in 42 (29%) patients. The difference in the ICH volume between MRI and CT were significantly larger in the CT wall sign-positive group than in -negative group (6.0 cm 3 versus 0.40 cm 3 , P <0.001). The presence of CT wall sign was significantly associated with putamen hemorrhage ( P =0.049), large hematoma > 11.36 cm 3 ( P =0.005), and niveau formation in the hematoma ( P <0.001). Conclusions: The presence of the CT wall sign suggests that the volume of an acute ICH may be larger than it appears on CT imaging. Key words: Acute intracerebral hemorrhage, Computed tomography, Magnetic resonance imaging, Perihematomal low-density area.

2011 ◽  
Vol 1 (2) ◽  
pp. 87-90
Author(s):  
Chen Wang Jin ◽  
Netra Rana ◽  
Yuan Wang ◽  
ShaoHui Ma ◽  
Min Li ◽  
...  

Objective: To assess the computed tomography (CT) imaging and magnetic resonance imaging (MRI) features of primary orbital lymphoma and to establish a differential diagnosis. Material & Methods: Fourteen patients (9 male and 5 female) suffering from primary orbital lymphoma underwent CT scanning with and without contrast. Pre- and post-contrast MRI scans were performed in 10 patients. Their ages ranged from 1.5 to 65 years (average age: 36 years). The course of diseases varied from 2 months to 16 years. Results: The diagnosis was confirmed pathologically in all cases. Lesions were bilateral in 4 cases and unilateral in 10 cases. Periorbital preseptal tissues were involved mainly in the upper lateral quadrant of the orbit. Focal masses were observed in 5 patients. Lesions that infiltrated the lacrimal gland, adjacent extraocular muscles and intraorbital tissues, along with the extraocular muscles, were found in other patients. The tumors that had advanced into intraorbital tissues and had involved extraocular muscles, displayed either a 'casting sign' or a 'ring sign'. Isodense soft-tissue masses with clear demarcation were found on plain CT film and lesions displayed low to intermediate signal intensity on T1- weighted MRI and relatively low or high signal intensity on T2-weighted MRI. The lesions demonstrated homogeneously marked enhancement on CT and MRI with contrast medium. Conclusion: CT imaging and MRI - particularly MRI - can demonstrate the location, configuration, inner structure and characteristic manifestations of the orbital lymphomas. This may assist the pre-operative diagnosis of these lesions. Key Words: Orbital tumor; Lymphoma; Pseudotumor; Computed tomography; Magnetic resonance imaging DOI: 10.3126/ajms.v1i2.3401Asian Journal of Medical Sciences 1 (2010) 87-90


2014 ◽  
Vol 38 (2) ◽  
pp. 212-214 ◽  
Author(s):  
Mehmet Beyazal ◽  
Necip Pirinççi ◽  
Alpaslan Yavuz ◽  
Sercan Özkaçmaz ◽  
Gülay Bulut

2010 ◽  
Vol 50 (8) ◽  
pp. 701-704 ◽  
Author(s):  
Atsushi ARAI ◽  
Takashi SASAYAMA ◽  
Junji KOYAMA ◽  
Atsushi FUJITA ◽  
Kohkichi HOSODA ◽  
...  

Stroke ◽  
2021 ◽  
Author(s):  
Jean François Hak ◽  
Grégoire Boulouis ◽  
Basile Kerleroux ◽  
Sandro Benichi ◽  
Sarah Stricker ◽  
...  

Background and Purpose: Pediatric nontraumatic intracerebral hemorrhage accounts for half of stroke in children. Early diagnostic of the causative underlying lesion is the first step toward prevention of hemorrhagic recurrence. We aimed to investigate the performance of arterial spin labeling sequence (ASL) in the acute phase etiological workup for the detection of an arteriovenous shunt (AVS: including malformation and fistula), the most frequent cause of pediatric nontraumatic intracerebral hemorrhage. Methods: Children with a pediatric nontraumatic intracerebral hemorrhage between 2011 and 2019 enrolled in a prospective registry were retrospectively included if they had undergone ASL-magnetic resonance imaging before any etiological treatment. ASL sequences were reviewed using cerebral blood flow maps by 2 raters for the presence of an AVS. The diagnostic performance of ASL was compared with admission computed tomography angiography, other magnetic resonance imaging sequences including contrast-enhanced sequences and subsequent digital subtraction angiography. Results: A total of 121 patients with pediatric nontraumatic intracerebral hemorrhage were included (median age, 9.9 [interquartile range, 5.8–13]; male sex 48.8%) of whom 76 (63%) had a final diagnosis of AVS. Using digital subtraction angiography as an intermediate reference, visual ASL inspection had a sensitivity and a specificity of, respectively, 95.9% (95% CI, 88.5%–99.1%) and 79.0% (95% CI, 54.4%–94.0%). ASL had a sensitivity, specificity, and accuracy of 90.2%, 97.2%, and 92.5%, respectively for the detection of the presence of an AVS, with near perfect inter-rater agreement (κ=0.963 [95% CI, 0.912–1.0]). The performance of ASL alone was higher than that of other magnetic resonance imaging sequences, individually or combined, and higher than that of computed tomography angiography. Conclusions: ASL has strong diagnostic performance for the detection of AVS in the initial workup of intracerebral hemorrhage in children. If our findings are confirmed in other settings, ASL may be a helpful diagnostic imaging modality for patients with pediatric nontraumatic intracerebral hemorrhage. REGISTRATION: URL: https://www.clinicaltrials.gov ; Unique identifiers: 3618210420, 2217698.


2016 ◽  
Vol 49 (2) ◽  
pp. 122-125 ◽  
Author(s):  
Daniel Alvarenga Fernandes ◽  
Ricardo Yoshio Zanetti Kido ◽  
Ricardo Hoelz de Oliveira Barros ◽  
Daniel Lahan Martins ◽  
Thiago José Penachim ◽  
...  

Abstract We present a case of immunoglobulin G4 (IgG4)-related disease with pancreatic and extrapancreatic involvement, including the biliary and renal systems. Given the importance of imaging methods for the diagnosis of IgG4-related disease and its differentiation from pancreatic adenocarcinoma, we emphasize important abdominal computed tomography and magnetic resonance imaging findings related to this recently recognized systemic autoimmune disease.


2019 ◽  
Vol 33 (08) ◽  
pp. 768-776 ◽  
Author(s):  
Si Heng Sharon Tan ◽  
Beatrice Ying Lim ◽  
Kiat Soon Jason Chng ◽  
Chintan Doshi ◽  
Francis K.L. Wong ◽  
...  

AbstractThe tibial tubercle–trochlear groove (TT–TG) distance was originally described for computed tomography (CT) but has recently been used on magnetic resonance imaging (MRI) without sufficient evidence demonstrating its validity on MRI. The current review aims to evaluate (1) whether there is a difference in the TT–TG distances measured using CT and MRI, (2) whether both the TT–TG distances measured using CT and MRI could be used to differentiate between patients with or without patellofemoral instability, and (3) whether the same threshold of 15 to 20 mm can be applied for both TT–TG distances measured using CT and MRI. The review was conducted using the preferred reporting items for systematic reviews and meta-analyses (PRSIMA) guidelines. All studies that compared TT–TG distances either (1) between CT and MRI or (2) between patients with and without patellofemoral instability were included. A total of 23 publications were included in the review. These included a total of 3,040 patients. All publications reported the TT–TG distance to be greater in patients with patellofemoral instability as compared to those without patellofemoral instability. This difference was noted for both TT–TG distances measured on CT and on MRI. All publications also reported the TT–TG distance measured on CT to be greater than that measured on MRI (mean difference [MD] = 1.79 mm; 95% confidence interval [CI]: 0.91–2.68). Pooling of the studies revealed that the mean TT–TG distance for the control group was 12.85 mm (95% CI: 11.71–14.01) while the mean TT–TG distance for patients with patellofemoral instability was 18.33 mm (95% CI: 17.04–19.62) when measured on CT. When measured on MRI, the mean TT–TG distance for the control group was 9.83 mm (95% CI: 9.11–10.54), while the mean TT–TG distance for patients with patellofemoral instability was 15.33 mm (95% CI: 14.24–16.42). Both the TTTG distances measured on CT and MRI could be used to differentiate between patients with and without patellofemoral instability. Patients with patellofemoral instability had significantly greater TT–TG distances than those without. However, the TT–TG distances measured on CT were significantly greater than that measured on MRI. Different cut-off values should, therefore, be used for TT–TG distances measured on CT and on MRI in the determination of normal versus abnormal values. Pooling of all the patients included in the review then suggest for 15.5 ± 1.5 mm to be used as the cut off for TT–TG distance measured on CT, and for 12.5 ± 2 mm to be used as the cut-off for TT–TG distance measured on MRI. The Level of evidence for this study is IV.


2013 ◽  
Vol 76 (9) ◽  
pp. 524-526 ◽  
Author(s):  
Hsien-Tzu Liu ◽  
Chui-Mei Tiu ◽  
Zen-Chung Weng ◽  
Yi-Hong Chou ◽  
Huai-Cheng Hsueh ◽  
...  

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