Lateral Inferotemporal Cortex Maintains Conceptual—Semantic Representations in Verbal Working Memory

2007 ◽  
Vol Early Access (Early Access) ◽  
pp. 080219115128817-15
Author(s):  
Christian J. Fiebach ◽  
Angela D. Friederici ◽  
Edward E. Smith ◽  
David Swinney
2007 ◽  
Vol 19 (12) ◽  
pp. 2035-2049 ◽  
Author(s):  
Christian J. Fiebach ◽  
Angela D. Friederici ◽  
Edward E. Smith ◽  
David Swinney

Verbal working memory, that is, the temporary maintenance of linguistic information in an activated state, is typically assumed to rely on phonological representations. Recent evidence from behavioral, neuropsychological, and electrophysiological studies, however, suggests that conceptual-semantic representations may also be maintained in an activated state. We developed a new semantic working memory task that involves the maintenance of a novel conceptual combination. Functional magnetic resonance imaging data acquired during the maintenance of conceptual combinations, relative to an item recognition task without the possibility of conceptual combination, demonstrate increased activation in the posterior left middle and inferior temporal gyri (known to be involved in conceptual representations) and left inferior frontal gyrus (known to be involved in semantic control processes). We suggest that this temporo-frontal system supports maintenance of conceptual information in working memory, with the frontal regions controlling the sustained activation of heteromodal conceptual representations in the inferior temporal cortex.


Neuron ◽  
2006 ◽  
Vol 51 (2) ◽  
pp. 251-261 ◽  
Author(s):  
Christian J. Fiebach ◽  
Jesse Rissman ◽  
Mark D'Esposito

Author(s):  
Jörg-Tobias Kuhn ◽  
Elena Ise ◽  
Julia Raddatz ◽  
Christin Schwenk ◽  
Christian Dobel

Abstract. Objective: Deficits in basic numerical skills, calculation, and working memory have been found in children with developmental dyscalculia (DD) as well as children with attention-deficit/hyperactivity disorder (ADHD). This paper investigates cognitive profiles of children with DD and/or ADHD symptoms (AS) in a double dissociation design to obtain a better understanding of the comorbidity of DD and ADHD. Method: Children with DD-only (N = 33), AS-only (N = 16), comorbid DD+AS (N = 20), and typically developing controls (TD, N = 40) were assessed on measures of basic numerical processing, calculation, working memory, processing speed, and neurocognitive measures of attention. Results: Children with DD (DD, DD+AS) showed deficits in all basic numerical skills, calculation, working memory, and sustained attention. Children with AS (AS, DD+AS) displayed more selective difficulties in dot enumeration, subtraction, verbal working memory, and processing speed. Also, they generally performed more poorly in neurocognitive measures of attention, especially alertness. Children with DD+AS mostly showed an additive combination of the deficits associated with DD-only and A_Sonly, except for subtraction tasks, in which they were less impaired than expected. Conclusions: DD and AS appear to be related to largely distinct patterns of cognitive deficits, which are present in combination in children with DD+AS.



2012 ◽  
Author(s):  
Klaus Oberauer ◽  
Stephan Lewandowsky

2007 ◽  
Author(s):  
Christelle Robert ◽  
Delphine Fagot ◽  
Thierry Lecerf ◽  
Anik de Ribaupierre

2009 ◽  
Author(s):  
Klaus Oberauer ◽  
Stephan Lewandowsky

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