Safety and Tolerability of Medium and High Doses of Mometasone Furoate/Formoterol (MF/F) Combination Treatment, Administered Via a Metered-Dose Inhaler (MDI), in Severe Asthma Patients Previously Treated with High-Dose Inhaled Corticosteroids (ICS).

2009 ◽  
Author(s):  
SF Weinstein ◽  
M White ◽  
J Corren ◽  
H Nolte
Keyword(s):  
Severe Asthma ◽  
Combination Treatment ◽  
Inhaled Corticosteroids ◽  
Dose Inhaler ◽  
High Dose ◽  
Metered Dose Inhaler ◽  
Metered Dose ◽  
Asthma Patients ◽  
Previously Treated ◽  
High Doses

scholarly journals Is it Difficult to Treat Asthma in Children?

2017 ◽  
Vol 1 (3) ◽  
pp. 23-30
Author(s):  
Anirban Mandal ◽  
Puneet Kaur Sahi
Keyword(s):  
Severe Asthma ◽  
Poor Response ◽  
Response To Therapy ◽  
Dose Inhaler ◽  
Metered Dose Inhaler ◽  
Metered Dose ◽  
Asthma Patients ◽  
Underlying Causes ◽  
Higher Doses ◽  
Substantial Morbidity

Asthma, the commonest chronic lung disease in childhood, is managed effectively with inhaled medications in most of the cases. But a subset of pediatric asthma patients continues to experience substantial morbidity even after higher doses of medications; they are referred to as problematic severe asthma. In many such cases, the apparent resistance to therapy is actually due to a number of remediable factors. These cases are called ‘difficult to treat asthma’. The physician dealing with a child with problematic severe asthma needs to follow a systematic step- wise approach to find any possible underlying causes of poor response to therapy. The evaluation starts with revisiting the diagnosis of asthma and goes through a checking the prescription, patient compliance, assessment for co-morbidities, environmental triggers and psychological factors. Only in a very small number of cases where no such remediable factors are identified, a diagnosis of severe therapy-resistant asthma is made and the child should be referred to a pediatric pulmonologist for further evaluation and therapy. Keywords: Severe therapy-resistant asthma; problematic severe asthma, metered dose inhaler, allergic rhinitis

scholarly journals Outcome of illustrated information leaflet on correct usage of asthma-metered dose inhaler

2019 ◽  
Vol 11 (1) ◽  
Author(s):  
Wendy Wrench ◽  
Lynette Van Dyk ◽  
Sunitha Srinivas ◽  
Ros Dowse
Keyword(s):  
Health Care ◽  
Health Care Professionals ◽  
Dose Inhaler ◽  
Metered Dose Inhaler ◽  
Low Literacy ◽  
Post Intervention ◽  
Care Clinic ◽  
Metered Dose ◽  
Asthma Patients

Background: Research globally has shown that metered dose inhaler (MDI) technique is poor, with patient education and regular demonstration critical in maintaining correct use of inhalers. Patient information containing pictorial aids improves understanding of medicine usage; however, manufacturer leaflets illustrating MDI use may not be easily understood by low-literacy asthma patients.Aim: To develop and evaluate the outcome of a tailored, simplified leaflet on correct MDI technique in asthma patients with limited literacy skills.Setting: A rural primary health care clinic in the Eastern Cape, South Africa.Methods: Pictograms illustrating MDI steps were designed to ensure cultural relevance. The design process of the leaflet was iterative and consultative involving a range of health care professionals as well as patients. Fifty-five rural asthma patients were recruited for the pre-post design educational intervention study. Metered dose inhaler technique was assessed using a checklist, and patients were then educated using the study leaflet. The principal researcher then demonstrated correct MDI technique. This process was repeated at follow-up 4 weeks later.Results: The number of correct steps increased significantly post intervention from 4.6 ± 2.2 at baseline to 7.9 ± 2.7 at follow-up (p 0.05). Statistically significant improvement of correct technique was established for 10 of the 12 steps. Patients liked the pictograms and preferred the study leaflet over the manufacturer leaflet.Conclusion: The tailored, simple, illustrated study leaflet accompanied by a demonstration of MDI technique significantly increased correct MDI technique in low-literacy patients. Patients approved of the illustrated, simple text leaflet, and noted its usefulness in helping them improve their MDI technique.

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