scholarly journals The Link Between the Shape of Maximal Expiratory Flow-Volume Curves and CT-Based Phenotypes in COPDGene

Author(s):  
K. Verstraete ◽  
N. Das ◽  
J.D. Crapo ◽  
E.K. Silverman ◽  
B.J. Make ◽  
...  
1979 ◽  
Vol 47 (1) ◽  
pp. 8-12 ◽  
Author(s):  
C. F. O'Cain ◽  
M. J. Hensley ◽  
E. R. McFadden ◽  
R. H. Ingram

We examined the bronchoconstriction produced by airway hypocapnia in normal subjects. Maximal expiratory flow at 25% vital capacity on partial expiratory flow-volume (PEFV) curves fell during hypocapnia both on air and on an 80% helium- 20% oxygen mixture. Density dependence also fell, suggesting predominantly small airway constriction. The changes seen on PEFV curves were not found on maximal expiratory flow-volume curves, indicating the inhalation to total lung capacity substantially reversed the constriction. Pretreatment with a beta-sympathomimetic agent blocked the response, whereas atropine pretreatment did not, suggesting that hypocapnia affects airway smooth muscle directly, not via cholinergic efferents.


1982 ◽  
Vol 29 (1) ◽  
pp. 30-36
Author(s):  
Song Hyun Nam ◽  
Hyun Ha Park ◽  
Re Hwe Kim ◽  
Sung Koo Han ◽  
Ye Won Kim ◽  
...  

CHEST Journal ◽  
1992 ◽  
Vol 102 (5) ◽  
pp. 1636-1637
Author(s):  
Sema Umut ◽  
Bilun Gemicioğlu ◽  
Nurhayat Yildirim

CHEST Journal ◽  
1988 ◽  
Vol 94 (4) ◽  
pp. 792-798 ◽  
Author(s):  
Françoise Neukirch ◽  
René Chansin ◽  
Renata Liard ◽  
Monique Levallois ◽  
Philippe Leproux

2015 ◽  
Vol 219 ◽  
pp. 30-35 ◽  
Author(s):  
Paolo B. Dominelli ◽  
Glen E. Foster ◽  
Jordan A. Guenette ◽  
Hans C. Haverkamp ◽  
Neil D. Eves ◽  
...  

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