5-Lipoxygenase Deficiency Prevents Respiratory Failure during Ventilator-induced Lung Injury

Invasive and noninvasive ventilation are important tools in the clinician’s armamentarium for managing acute respiratory failure. Although these modalities do not treat the underlying disease, they can provide the necessary oxygenation and ventilatory support until the causal pathology resolves. Care must be taken as even appropriate application can cause harm. Knowledge of pulmonary mechanics, appreciation of the basic machine settings, and an understanding of how common and advanced modes function allows the clinician to optimally tailor support to the patient while limiting iatrogenic injury. This second chapter reviews indications for mechanical ventilation, routine management, troubleshooting, and liberation from mechanical ventilation This review contains 6 figures, 7 tables and 60 references Keywords: Mechanical ventilation, lung protective ventilation, sedation, ventilator-induced lung injury, liberation from mechanical ventilation

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Current Applications for the Use of Extracorporeal Carbon Dioxide Removal in Critically Ill Patients

BioMed Research International ◽

10.1155/2016/9781695 ◽

2016 ◽

Vol 2016 ◽

pp. 1-8 ◽

Cited By ~ 21

Author(s):

Luigi Camporota ◽

Nicholas Barrett

Keyword(s):

Carbon Dioxide ◽

Mechanical Ventilation ◽

Respiratory Failure ◽

Lung Injury ◽

Carbon Dioxide Removal ◽

Extracorporeal Carbon Dioxide Removal ◽

Ventilator Induced Lung Injury ◽

Patient Groups ◽

Protective Mechanical Ventilation

Mechanical ventilation in patients with respiratory failure has been associated with secondary lung injury, termed ventilator-induced lung injury. Extracorporeal venovenous carbon dioxide removal (ECCO2R) appears to be a feasible means to facilitate more protective mechanical ventilation or potentially avoid mechanical ventilation in select patient groups. With this expanding role of ECCO2R, we aim to describe the technology and the main indications of ECCO2R.

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Partial liquid ventilation and positive end-expiratory pressure reduce ventilator-induced lung injury in an ovine model of acute respiratory failure

Critical Care Medicine ◽

10.1097/00003246-200201000-00026 ◽

2002 ◽

Vol 30 (1) ◽

pp. 182-189 ◽

Cited By ~ 9

Author(s):

Craig A. Reickert ◽

Preston B. Rich ◽

Stefania Crotti ◽

Simon A. Mahler ◽

Samir S. Awad ◽

...

Keyword(s):

Respiratory Failure ◽

Lung Injury ◽

Acute Respiratory Failure ◽

Partial Liquid Ventilation ◽

Positive End Expiratory Pressure ◽

Ovine Model ◽

Liquid Ventilation ◽

Ventilator Induced Lung Injury

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Noninvasive and Invasive Ventilatory Support II

10.2310/tywc.8366 ◽

2018 ◽

Author(s):

Pauline K. Park ◽

Nicole L Werner ◽

Carl Haas

Keyword(s):

Mechanical Ventilation ◽

Respiratory Failure ◽

Lung Injury ◽

Acute Respiratory Failure ◽

Ventilatory Support ◽

Underlying Disease ◽

Protective Ventilation ◽

Lung Protective Ventilation ◽

Pulmonary Mechanics ◽

Ventilator Induced Lung Injury

Invasive and noninvasive ventilation are important tools in the clinician’s armamentarium for managing acute respiratory failure. Although these modalities do not treat the underlying disease, they can provide the necessary oxygenation and ventilatory support until the causal pathology resolves. Care must be taken as even appropriate application can cause harm. Knowledge of pulmonary mechanics, appreciation of the basic machine settings, and an understanding of how common and advanced modes function allows the clinician to optimally tailor support to the patient while limiting iatrogenic injury. This second chapter reviews indications for mechanical ventilation, routine management, troubleshooting, and liberation from mechanical ventilation This review contains 6 figures, 7 tables and 60 references Keywords: Mechanical ventilation, lung protective ventilation, sedation, ventilator-induced lung injury, liberation from mechanical ventilation

Download Full-text