scholarly journals Magnetic Resonance Imaging of Ventilation and Perfusion Changes in Response to Pulmonary Endarterectomy in Chronic Thromboembolic Pulmonary Hypertension

2014 ◽  
Vol 190 (5) ◽  
pp. e18-e19 ◽  
Author(s):  
Helen Marshall ◽  
David G. Kiely ◽  
Juan Parra-Robles ◽  
David Capener ◽  
Martin H. Deppe ◽  
...  
2006 ◽  
Vol 17 (1) ◽  
pp. 11-21 ◽  
Author(s):  
Karl-Friedrich Kreitner ◽  
R. Peter Kunz ◽  
Sebastian Ley ◽  
Katja Oberholzer ◽  
Daniel Neeb ◽  
...  

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Christian Alcaraz Frederiksen ◽  
Farhad Waziri ◽  
Steffen Ringgaard ◽  
Søren Mellemkjær ◽  
Tor Skibsted Clemmensen ◽  
...  

Abstract Background To investigate changes in tricuspid annulus (TA) and tricuspid valve (TV) morphology among chronic thromboembolic pulmonary hypertension (CTEPH) patients before and 12 months after pulmonary thromboendarterectomy (PEA) and compare these findings to normal control subjects. Methods 20 CTEPH patients and 20 controls were enrolled in the study. The patients were examined with echocardiography, right heart catherization and cardiac magnetic resonance imaging prior to PEA and 12 months after. Results Right atrium (RA) volume was significantly reduced from baseline to 12 months after PEA (30 ± 9 vs 23 ± 5 ml/m2, p < 0.005). TA annular area in systole remained unchanged (p = 0.11) and was comparable to controls. The leaflet area, tenting volume and tenting height in systole were significantly increased at baseline but decreased significantly with comparable values to controls after 12 months (p < 0.005). There was correlation between the changes of right ventricular-pulmonary artery coupling and changes of TV tenting height (r = − 0.54, p = 0.02), TV tenting volume (r = − 0.73, p < 0.001) and TV leaflet area (− 0.57, p = 0.01) from baseline to 12 months after PEA. Tricuspid regurgitation jet area/RA area was significantly (p < 0.01) reduced from baseline (30 ± 13%) to 12 months after PEA (9 ± 10%). Conclusion In CTEPH patients selected for PEA, TV tenting height, volume and valve area are significantly increased whereas annulus size and shape are less affected. The alterations in TV morphology are fully reversed after PEA and correlates to improvements of right ventricular-pulmonary arterial coupling.


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