scholarly journals Large Granular Lymphocytes Leukemia: A Case Report with a Review of the Literature

2020 ◽  
Vol 8 (1) ◽  
pp. 1
Author(s):  
Maryam Mouamin ◽  
Ghita Badou ◽  
Hicham Yahyaoui ◽  
Imane Benjelloun ◽  
Mohamed Raissi ◽  
...  
2016 ◽  
Vol 69 (11-12) ◽  
pp. 376-378 ◽  
Author(s):  
Vanja Zeremski ◽  
Aleksandar Savic ◽  
Vesna Cemerikic-Martinovic ◽  
Ivana Milosevic ◽  
Marina Dragicevic ◽  
...  

Case report. A 41-year-old man presented with anemia, lymphocytosis and splenomegaly. T-cell large granular lymphocyte leukemia was diagnosed based on lymphocytosis of T-cell large granular lymphocytes, characteristic immunophenotype (CD3+, CD8+, CD16+, CD57+) of the lymphocytes and clonally rearranged T-cell receptor genes. Therapy indication was transfusion-dependent anemia. Initial cyclosporine therapy and low-dose oral methotrexate failed to control anemia and lymphocytosis. Yet, a complete clinical and hematological response (without molecular remission) was achieved and sustained when cyclosporine was reintroduced into the therapy. Conclusion. Our case confirms that cyclosporine therapy is effective in treating T-cell large granular lymphocyte leukemia and suggests that indefinite treatment may not be needed to maintain the response.


2017 ◽  
Vol 32 (suppl_3) ◽  
pp. iii730-iii731 ◽  
Author(s):  
Gaetano Alfano ◽  
Francesco Fontana ◽  
Elisabetta Colaci ◽  
Andrea Messerotti ◽  
Leonardo Potenza ◽  
...  

Reumatismo ◽  
2011 ◽  
Vol 54 (4) ◽  
Author(s):  
F. Ingegnoli ◽  
M. Arreghini ◽  
B. Panni ◽  
R. Capra ◽  
F. Galbiati ◽  
...  

1992 ◽  
Vol 40 (2) ◽  
pp. 135-145 ◽  
Author(s):  
Tsieh Sun ◽  
Philip Schulman ◽  
Jonathan Kolitz ◽  
Myron Susin ◽  
Judith Brody ◽  
...  

1999 ◽  
Vol 19 (3) ◽  
pp. 328-335
Author(s):  
Shanop Shuangshoti Shuangshoti ◽  
Samruay Shuangshoti

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