Time-Dependent Effects of Elevated Intraocular Pressure on Optic Nerve Head Axonal Transport and Cytoskeleton Proteins

2008 ◽  
Vol 49 (3) ◽  
pp. 986 ◽  
Author(s):  
Chandrakumar Balaratnasingam ◽  
William H. Morgan ◽  
Louise Bass ◽  
Stephen J. Cringle ◽  
Dao-Yi Yu
Keyword(s):  
Intraocular Pressure ◽  
Optic Nerve ◽  
Axonal Transport ◽  
Optic Nerve Head ◽  
Time Dependent ◽  
Elevated Intraocular Pressure

scholarly journals Optic Nerve Head Astrocytes Display Axon-Dependent and -Independent Reactivity in Response to Acutely Elevated Intraocular Pressure

2019 ◽  
Vol 60 (1) ◽  
pp. 312 ◽  
Author(s):  
Shandiz Tehrani ◽  
Lauren Davis ◽  
William O. Cepurna ◽  
R. Katherine Delf ◽  
Diana C. Lozano ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Optic Nerve ◽  
Optic Nerve Head ◽  
Elevated Intraocular Pressure

scholarly journals Astrocyte Structural and Molecular Response to Elevated Intraocular Pressure Occurs Rapidly and Precedes Axonal Tubulin Rearrangement within the Optic Nerve Head in a Rat Model

PLoS ONE ◽  
2016 ◽  
Vol 11 (11) ◽  
pp. e0167364 ◽  
Author(s):  
Shandiz Tehrani ◽  
Lauren Davis ◽  
William O. Cepurna ◽  
Tiffany E. Choe ◽  
Diana C. Lozano ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Optic Nerve ◽  
Optic Nerve Head ◽  
Rat Model ◽  
Molecular Response ◽  
Elevated Intraocular Pressure

The Impact of Acutely Elevated Intraocular Pressure on the Porcine Optic Nerve Head

2011 ◽  
Vol 52 (9) ◽  
pp. 6192 ◽  
Author(s):  
Naeem Fatehee ◽  
Paula K. Yu ◽  
William H. Morgan ◽  
Stephen J. Cringle ◽  
Dao-Yi Yu
Keyword(s):  
Intraocular Pressure ◽  
Optic Nerve ◽  
Optic Nerve Head ◽  
Elevated Intraocular Pressure ◽  
The Impact

The Effect of Nonlinear Scleral Properties on Optic Nerve Head Biomechanics

2007 ◽  
Author(s):  
Armin Eilaghi ◽  
Ian A. Sigal ◽  
Christian G. Olesen ◽  
Inka Tertinegg ◽  
John G. Flanagan ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Optic Nerve ◽  
Optic Nerve Head ◽  
Progressive Damage ◽  
Ocular Diseases ◽  
Glaucomatous Damage ◽  
Elevated Intraocular Pressure ◽  
Biomechanical Factors

Glaucoma is a group of potentially blinding ocular diseases caused by gradual and progressive damage to the optic nerve, and is usually associated with elevated intraocular pressure (IOP) [1]. This damage occurs at the optic nerve head (ONH), the site where the optic nerve axons leave the posterior eye. IOP-related biomechanical factors are hypothesized to play a key role in the pathogenesis of glaucomatous damage [2].

scholarly journals A method to quantify regional axonal transport blockade at the optic nerve head after short term intraocular pressure elevation in mice

2020 ◽  
Vol 196 ◽  
pp. 108035 ◽  
Author(s):  
Arina Korneva ◽  
Julie Schaub ◽  
Joan Jefferys ◽  
Elizabeth Kimball ◽  
Mary Ellen Pease ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Optic Nerve ◽  
Axonal Transport ◽  
Optic Nerve Head ◽  
Short Term ◽  
Pressure Elevation ◽  
Intraocular Pressure Elevation
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