Correlation Between Subfoveal Choroidal Thickness and the Severity or Progression of Nonexudative Age-Related Macular Degeneration

2013 ◽  
Vol 54 (12) ◽  
pp. 7812 ◽  
Author(s):  
Jin Young Lee ◽  
Dong Hoon Lee ◽  
Joo Yong Lee ◽  
Young Hee Yoon
Keyword(s):  
Macular Degeneration ◽  
Choroidal Thickness ◽  
Age Related Macular Degeneration ◽  
Subfoveal Choroidal Thickness ◽  
Age Related

Subfoveal choroidal thickness in typical age-related macular degeneration and polypoidal choroidal vasculopathy

2011 ◽  
Vol 249 (8) ◽  
pp. 1123-1128 ◽  
Author(s):  
Hideki Koizumi ◽  
Tetsuya Yamagishi ◽  
Taizo Yamazaki ◽  
Ryo Kawasaki ◽  
Shigeru Kinoshita
Keyword(s):  
Macular Degeneration ◽  
Polypoidal Choroidal Vasculopathy ◽  
Choroidal Thickness ◽  
Age Related Macular Degeneration ◽  
Subfoveal Choroidal Thickness ◽  
Age Related ◽  
Choroidal Vasculopathy

Relation between subfoveal choroidal thickness and visual acuity in patients with wet and dry age-related macular degeneration

2014 ◽  
Vol 92 ◽  
pp. 0-0
Author(s):  
K ZABADANI ◽  
L HERRERA ◽  
FJ ASCASO ◽  
C CARAMELLO ◽  
C ALMENARA ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Macular Degeneration ◽  
Choroidal Thickness ◽  
Age Related Macular Degeneration ◽  
Subfoveal Choroidal Thickness ◽  
Age Related

scholarly journals Analysis of Short-Term Change in Subfoveal Choroidal Thickness in Eyes With Age-Related Macular Degeneration Using Optical Coherence Tomography

2014 ◽  
Vol 45 (1) ◽  
pp. 32-37 ◽  
Author(s):  
Jordana G. Fein ◽  
Lauren A. Branchini ◽  
Varsha Manjunath ◽  
Caio V. Regatieri ◽  
James G. Fujimoto ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Degeneration ◽  
Choroidal Thickness ◽  
Age Related Macular Degeneration ◽  
Optical Coherence ◽  
Short Term ◽  
Subfoveal Choroidal Thickness ◽  
Age Related ◽  
Short Term Change ◽  
Term Change

Subfoveal choroidal thickness as a prognostic factor in exudative age-related macular degeneration

2018 ◽  
Vol 103 (7) ◽  
pp. 918-921 ◽  
Author(s):  
Jaya B Kumar ◽  
Karen M Wai ◽  
Justin P Ehlers ◽  
Rishi P Singh ◽  
Aleksandra V Rachitskaya
Keyword(s):  
Prognostic Factor ◽  
Macular Degeneration ◽  
Choroidal Thickness ◽  
Age Related Macular Degeneration ◽  
Intravitreal Injections ◽  
Imaging Biomarkers ◽  
Exudative Amd ◽  
Subfoveal Choroidal Thickness ◽  
Age Related ◽  
The Mean

AimsTo investigate the relationship between subfoveal choroidal thickness (SFCT), visual acuity (VA), optical coherence tomography (OCT) features and total anti-vascular endothelial growth factor (VEGF) treatments to determine whether SFCT serves as a prognostic factor in age-related macular degeneration (AMD).MethodsThis is a retrospective case series of 62 consecutive treatment-naive patients with exudative AMD followed for 1 year and treated with treat-and-extend or pro re nata anti-VEGF protocols. SFCT was measured at three locations using Cirrus HD-OCT (the foveal centre and 500 um nasal and temporal to the fovea) at presentation, 3, 6 and 12 months. Demographic characteristics, OCT imaging biomarkers and VA were recorded.ResultsMean SFCT at baseline was 187 µm (range: 70–361 µm). There was a trend of decreasing SFCT at 1 year (173 µm) compared with 3 months (175 µm) and baseline (188 µm) (p=0.2). There was no correlation between baseline SFCT and presence of subretinal fluid (p=0.2), intraretinal fluid (p=0.6) or subretinal hyper-reflective material (p=0.4) at baseline. The mean number of injections at 1 year was 6.6 (range: 2–12). Increased SFCT at baseline showed statistically significant correlation with a higher number of intravitreal injections at 1 year (p=0.004). Eyes with SFCT>1 SD above the mean required 50% more injections compared with others. There was no association between SFCT on presentation with baseline and 1 year VA (p=0.7 and p=0.2).ConclusionsSFCT in naïve patients with exudative AMD may be an important prognostic tool in determining treatment burden. Patients with thicker subfoveal choroid may require increased intravitreal injections.

Distinguishing Central Serous Chorioretinopathy From Neovascular Age-Related Macular Degeneration: A Prospective Study

2020 ◽  
Vol 4 (4) ◽  
pp. 293-299
Author(s):  
Parampal S. Grewal ◽  
Steven R.J. Lapere ◽  
Christopher J. Rudnisky ◽  
Rizwan Somani ◽  
Matthew T.S. Tennant
Keyword(s):  
Decision Making ◽  
Macular Degeneration ◽  
Central Serous Chorioretinopathy ◽  
Choroidal Thickness ◽  
Clinical Decision Making ◽  
Clinical Decision ◽  
Age Related Macular Degeneration ◽  
Subfoveal Choroidal Thickness ◽  
Pigment Epithelial ◽  
Age Related

Purpose: This article identifies clinical features that differentiate central serous chorioretinopathy (CSR) from neovascular age-related macular degeneration (nAMD) and uses this information to develop a diagnostic tool. Methods: A prospective observational study was conducted of patients with a new diagnosis of CSR, nAMD, or indeterminate presentation. All patients underwent clinical assessment, axial length measurement, enhanced-depth imaging–optical coherence tomography, and intravenous fluorescein angiography. A final consensus diagnosis was derived following review of these factors. Results: A total of 56 eyes of 56 patients were enrolled (CSR = 34; nAMD = 22). The subfoveal choroidal thickness was greater in the CSR group (421 ± 106 µm) than the nAMD group (219 ± 91 µm, P < .001). The following odds ratio of CSR reached statistical significance: age 70 and younger (72.00, 95% CI: 11.99-432.50), subfoveal choroidal thickness greater than or equal to 300 µm (33.92, 95% CI: 4.06-283.18), dome-shaped neurosensory detachment (13.24, 95% CI: 3.22-54.45), retinal pigment epithelial changes (0.31, 95% CI: 0.10-0.97), subretinal hyperreflective material (0.11, 95% CI: 0.03-0.42), and fibrovascular pigment epithelial detachment (0.05, 95% CI: 0.01-0.47). A stepwise CSR vs nAMD clinical decision-making algorithm is proposed. Conclusions: Choroidal thickness is increased in CSR when compared with nAMD. The presented odds ratios and the CSR vs nAMD clinical decision-making tool can be applied to distinguish CSR from nAMD.

Association Between Subfoveal Choroidal Thickness, Reticular Pseudodrusen, and Geographic Atrophy in Age-Related Macular Degeneration

2015 ◽  
Vol 46 (5) ◽  
pp. 513-521 ◽  
Author(s):  
Mariana R. Thorell ◽  
Raquel Goldhardt ◽  
Renata Portella Nunes ◽  
Carlos Alexandre de Amorim Garcia Filho ◽  
Ashkan M. Abbey ◽  
...  
Keyword(s):  
Macular Degeneration ◽  
Choroidal Thickness ◽  
Geographic Atrophy ◽  
Age Related Macular Degeneration ◽  
Subfoveal Choroidal Thickness ◽  
Reticular Pseudodrusen ◽  
Age Related
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