scholarly journals Perception of Haidinger Brushes in Macular Disease Depends on Macular Pigment Density and Visual Acuity

2016 ◽  
Vol 57 (3) ◽  
pp. 1448 ◽  
Author(s):  
Philipp L. Müller ◽  
Simone Müller ◽  
Martin Gliem ◽  
Kristina Küpper ◽  
Frank G. Holz ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Macular Pigment ◽  
Macular Disease

Eccentric Visual Acuity in Patients with Macular Disease

Ophthalmology ◽  
1985 ◽  
Vol 92 (11) ◽  
pp. 1550-1553 ◽  
Author(s):  
Michael J. Harris ◽  
David Robins ◽  
Joseph M. Dieter ◽  
Stuart L. Fine ◽  
David L. Guyton
Keyword(s):  
Visual Acuity ◽  
Macular Disease

scholarly journals EFFECT OF ANTI-VEGF THERAPY ON THE STRUCTURAL STATE OF THE RETINA IN DIABETIC MACULAR EDEMA

2016 ◽  
Vol 1 (6) ◽  
pp. 24-27
Author(s):  
Бикбов ◽  
Mukharram Bikbov ◽  
Файзрахманов ◽  
Rinat Fayzrakhmanov ◽  
Зайнуллин ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Macular Edema ◽  
Diabetic Macular Edema ◽  
Optical Density ◽  
Structural State ◽  
Central Area ◽  
Macular Pigment ◽  
Optical Coherence ◽  
Macular Pigment Optical Density ◽  
Anti Vegf

Objective: to analyze the structural state of the central area of the retina in diabetic macular edema in the background anti-VEGF therapy.Methods. The study included 38patients (40eyes) with diabetic macular edema. All patients received anti-VEGF-ranibizumab therapy at a dose of 0.05ml. The results were analyzed after three intravitreal injections with 1month interval. We assessed visual acuity, morphological and anatomical structure of the macular area, the sensitivity of the retina and macular pigment optical densityResults. Analyzing optical density of the macular pigment we revealed a significant increase of all parameters in 73% of patients after the therapy. The average value of the optical density before treatment was at 0.102±0.01du, on the background of anti-VEGF-therapy this figure went up to 0.213±0.01 (p<0.05). According to the optical coherence to-mography average retinal thickness before treatment made 404.62±15.23μm, after the treatment – 300.91±6.43μm (р<0,05). When comparing data of optical coherence tomography and macular pigment optical density we revealed more pronounced decrease in the macular pigment optical density in the area of the retinal edema and a significant increase in the basic parameters on the background of the therapy.Conclusion. Anti-VEGF-therapy significantly improves visual acuity, the recovery profile of macular edema and reduces the zone in patients with diabetic macular edema.

Visual evoked potentials in relation to visual acuity in macular disease

2001 ◽  
Vol 79 (3) ◽  
pp. 271-276 ◽  
Author(s):  
Chisako Negishi ◽  
Michihiko Takasoh ◽  
Naoya Fujimoto ◽  
Yoshihiko Tsuyama ◽  
Emiko Adachi-Usami
Keyword(s):  
Visual Acuity ◽  
Evoked Potentials ◽  
Visual Evoked Potentials ◽  
Macular Disease ◽  
Visual Evoked

Long-term outcomes of penetrating keratoplasty for corneal complications of herpes zoster ophthalmicus

2019 ◽  
pp. bjophthalmol-2018-313602 ◽  
Author(s):  
Thaís Shiota Tanaka ◽  
Christopher Thomas Hood ◽  
Matthias Frank Kriegel ◽  
Leslie Niziol ◽  
H Kaz Soong
Keyword(s):  
Visual Acuity ◽  
Herpes Zoster ◽  
Penetrating Keratoplasty ◽  
Long Term Outcomes ◽  
Herpes Zoster Ophthalmicus ◽  
Macular Disease ◽  
Preoperative Risk Factors ◽  
Visual Potential

Background/AimTo review the long-term outcomes of penetrating keratoplasty (PKP) for corneal complications of herpes zoster ophthalmicus (HZO).MethodsWe reviewed the medical records of 53 eyes of 53 patients who underwent PKP due to corneal complications of HZO at the Kellogg Eye Center.ResultsThe mean age of patients at the time of PKP was 68.0±16.4 years, with a follow-up of 4.0±3.8 years and quiescent period of 6.5±5.3 years from active HZO to PKP. Preoperatively, 25 (47.2%) eyes were completely anaesthetic, while 16 (30.2%) had deep corneal neovascularisation in four quadrants. Comorbid ocular disease, including cataract, glaucoma and macular disease, was present in 25 (47.2%) eyes. Twenty patients (37.8%) received acyclovir for the entire postoperative period. There were no recurrences of zoster keratitis in any eye. The most common complications were difficulty healing the ocular surface (12/53, 22.6%) and glaucoma (14/53, 26.4%). Thirty per cent of the eyes required one or more additional postoperative procedures, most commonly tarsorrhaphy (10/53, 18.9%) and amniotic membrane graft (6/53, 11.3%). At 1, 2–4 and ≥5 years, 94%, 82% and 70% grafts remained clear, respectively. Visual acuity improved at 1 year postoperatively (p<0.0001), but this improvement was not sustained. There was no significant benefit of long-term acyclovir on visual acuity (p=0.2132) or graft survival (p=0.241).ConclusionsEven in eyes with significant preoperative risk factors, PKP for the corneal complications of HZO can achieve favourable tectonic and visual results. Although most grafts remained clear, long-term visual potential may be limited by comorbid ocular diseases. Prophylactic postoperative oral acyclovir did not improve outcomes.

Paradoxical Improvement of Visual Acuity in Macular Disease

2010 ◽  
Vol 35 (7) ◽  
pp. 651-656 ◽  
Author(s):  
Satoshi Ishiko ◽  
Frans van de Velde ◽  
Akitoshi Yoshida
Keyword(s):  
Visual Acuity ◽  
Macular Disease

Relationship between macular pigment and visual acuity in eyes with early age-related macular degeneration

2013 ◽  
Vol 91 (4) ◽  
pp. e298-e303 ◽  
Author(s):  
María C. Puell ◽  
Catalina Palomo-Alvarez ◽  
Ana R. Barrio ◽  
Fernando J. Gómez-Sanz ◽  
María Jesús Pérez-Carrasco
Keyword(s):  
Visual Acuity ◽  
Macular Degeneration ◽  
Macular Pigment ◽  
Age Related Macular Degeneration ◽  
Early Age ◽  
Age Related

scholarly journals Smartphone-based remote monitoring of vision in macular disease enables early detection of worsening pathology and need for intravitreal therapy

2021 ◽  
Vol 28 (1) ◽  
pp. e100310
Author(s):  
Meriam Islam ◽  
Stafford Sansome ◽  
Radha Das ◽  
Marko Lukic ◽  
Kelvin Yi Chong Teo ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Remote Monitoring ◽  
Home Monitoring ◽  
Central Macular Thickness ◽  
Traffic Light ◽  
Macular Disease ◽  
Intravitreal Therapy ◽  
Need For Treatment ◽  
System A ◽  
Macular Diseases

Background/aimsTo assess the outcomes of home monitoring of distortion caused by macular diseases using a smartphone-based application (app), and to examine them with hospital-based assessments of visual acuity (VA), optical coherence tomography-derived central macular thickness (CMT) and the requirement of intravitreal injection therapy.DesignObservational study with retrospective analysis of data.MethodsParticipants were trained in the correct use of the app (Alleye, Oculocare, Zurich, Switzerland) in person or by using video and telephone consultations. Automated threshold-based alerts were communicated based on a traffic light system. A ‘threshold alarm’ was defined as three consecutive ‘red’ scores, and turned into a ‘persistent alarm’ if present for greater than a 7-day period. Changes of VA and CMT, and the requirement for intravitreal therapy after an alarm were examined.Results245 patients performing a total of 11 592 tests (mean 46.9 tests per user) were included and 85 eyes (164 alarms) examined. Mean drop in VA from baseline was −4.23 letters (95% CI: −6.24 to −2.22; p<0.001) and mean increase in CMT was 29.5 µm (95% CI: −0.08 to 59.13; p=0.051). Sixty-six eyes (78.5%) producing alarms either had a drop in VA, increase in CMT or both and 60.0% received an injection. Eyes with persistent alarms had a greater loss of VA, −4.79 letters (95% CI: −6.73 to −2.85; p<0.001) or greater increase in CMT, +87.8 µm (95% CI: 5.2 to 170.4; p=0.038).ConclusionSmartphone-based self-tests for macular disease may serve as reliable indicators for the worsening of pathology and the need for treatment.

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