Duloxetine-Related Growth of Putamen and Brainstem in First-Onset Drug-Naive Major Depressive Disorder With Panic Disorder: A Case Series

2011 ◽  
Vol 23 (2) ◽  
pp. E40-E41 ◽  
Author(s):  
Chien-Han Lai
Keyword(s):  
Major Depressive Disorder ◽  
Panic Disorder ◽  
Depressive Disorder ◽  
Case Series ◽  
Major Depressive ◽  
First Onset ◽  
Drug Naïve

Subcortical structural abnormalities of first onset drug naïve major depressive disorder with panic disorder patients

2011 ◽  
Vol 26 (S2) ◽  
pp. 936-936
Author(s):  
C.-H. Lai
Keyword(s):  
Major Depressive Disorder ◽  
Panic Disorder ◽  
Depressive Disorder ◽  
Rating Scales ◽  
Surface Model ◽  
Subcortical Structures ◽  
Major Depressive ◽  
Clinical Rating ◽  
Structural Abnormalities ◽  
Drug Naïve

ObjectiveThis study was designed to apply subcortical analysis of first episode drug naïve major depressive disorder with panic disorder patients.MethodAll the participating subjects received scales rating for depression and panic disorder. 15 patients and 15 healthy controls were compared to explore the differences of subcortical structures, such as hippocampus, putamen and thalamus. A new semi-automatic toolbox for computing subcortical areas by a shape and surface model was utilized for the comparison. The volumes of subcortical structures were also compared by using nonparametric t test of SPSS software to support the findings from the FSL FIRST toolbox (FMRIB Software Library, FMRIB's Integrated Registration and Segmentation Tool).ResultsThe patient group had significantly lower volumes in the left hippocampus, thalamus and putamen. The volumetric differences were also significant in these areas (2 tailed p < 0.05; Mann-Whitney U test). The volumes of thalamus and putamen were also well correlated with clinical rating scales. The relationship between left hippocampal volumes and clinical rating scales was modest. The volumes of right hippocampus were not correlated with clinical rating scales.ConclusionsThe structural abnormalities of putamen and thalamus might represent a specific pathology for major depressive disorder co-morbid with panic disorder. The limited deficits of hippocampal volumes should represent an intermediate type between major depressive disorder and panic disorder. The co-morbidity might have a different subcortical pathology.

Heart rate variability in drug-naïve patients with panic disorder and major depressive disorder

2009 ◽  
Vol 33 (8) ◽  
pp. 1474-1478 ◽  
Author(s):  
Mitsuru Kikuchi ◽  
Akira Hanaoka ◽  
Tomokazu Kidani ◽  
Gerard Bastiaan Remijn ◽  
Yoshio Minabe ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Major Depressive Disorder ◽  
Panic Disorder ◽  
Depressive Disorder ◽  
Major Depressive ◽  
Drug Naïve

Brief Report: Major Depressive Disorder with Psychotic Features in Williams Syndrome: A Case Series

2017 ◽  
Vol 48 (3) ◽  
pp. 947-952 ◽  
Author(s):  
Francisca Valdes ◽  
Christopher J. Keary ◽  
Jennifer E. Mullett ◽  
Michelle L. Palumbo ◽  
Jessica L. Waxler ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Williams Syndrome ◽  
Case Series ◽  
Major Depressive ◽  
Psychotic Features
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