scholarly journals Effect of CO2 on the Perilymphatic Oxygen Tension in Cats

1977 ◽  
Vol 86 (2) ◽  
pp. 164-171 ◽  
Author(s):  
K. Murata ◽  
U. Fisch

A microelectrode with a tip of 100μ permitting recording of the oxygen tension in the perilymphatic space according to the polarographic principle and having a minimal drift of 1–2.5% per hour has been developed. The effects of apnea, hypo- and hyperventilation as well as those of inhalation of pure oxygen, and CO2 upon the perilymphatic Po2 have been measured by placing the electrode in the perilymph through the fenestrated stapedial footplate of 87 adult cats. The correlation between the arterial Pco2 and the perilymphatic Po2 is so close that even hypo- or hyperventilation in presence of air does influence the oxygen content of the perilymphatic space. In view of the effect of the smallest accumulation of alveolar CO2, particular attention has to be paid to the system used for respiration of the experimental animal, when determining the action of drugs or inhaled gas mixtures on the oxygenation of the inner ear fluids. The measurement of the perilymphatic oxygen tension also indicates that the rate of blood flow cannot be used to deduct with accuracy the actual degree of oxygenation of the inner ear fluids.

1982 ◽  
Vol 234 (2) ◽  
pp. 125-130 ◽  
Author(s):  
Matti Anniko ◽  
Aron Sobin ◽  
Romuald Wr�blewski
Keyword(s):  
X Ray ◽  

1979 ◽  
Vol 135 (5) ◽  
pp. 637-646 ◽  
Author(s):  
Louis L.H. Peeters ◽  
Roger E. Sheldon ◽  
M. Douglas Jones ◽  
Edgar L. Makowski ◽  
Giacomo Meschia

1979 ◽  
Vol 88 (5) ◽  
pp. 626-629
Author(s):  
N. Yagi ◽  
U. Fisch

The effect of the intravenous injection of cholinergic drugs on perilymphatic oxygen tension (Po2) was measured using the polarographic method in 20 cats. Acetylcholine, pilocarpine and neostigmine produced minimal but statistically significant changes in perilymphatic Po2. Atropine and scopolamine did not influence the Po2 of the perilymphatic space. The reported results show that under normal conditions the cholinergic receptors of the vestibular vessels have little effect on the permeability of arterial Po2.


1983 ◽  
Vol 58 (4) ◽  
pp. 526-530 ◽  
Author(s):  
Nariyuki Hayashi ◽  
Barth A. Green ◽  
Mayra Gonzalez-Carvajal ◽  
Joseph Mora ◽  
Richard P. Veraa

✓ Using a reliable and reproducible microelectrode technique, consistent simultaneous measurements of local spinal cord blood flow (SCBF), tissue oxygen tension, and tissue oxygen consumption were made at cervical, thoracic, and lumbar levels in the rat spinal cord. These observations showed that the metabolic state is maintained constant along the cord, despite significant variations in vasculature. The physiological and anatomical aspects of these findings are discussed.


1990 ◽  
Vol 259 (5) ◽  
pp. E639-E643 ◽  
Author(s):  
I. W. Gallen ◽  
I. A. Macdonald

Two methods of hand heating [warmed blanket 40 degrees C (WB) and warm-air box 55 degrees C (WA)] were compared with the effect of no heating (control) in six healthy females. After 30 min baseline, the left hand was either heated for 1 h or not heated. Measurements were made of skin temperature (ST), core temperature (CT), right forearm (FBF) and skin blood flow (SBF), and right forearm deep venous blood oxygen content with and without occlusion of the hand circulation. CT rose above baseline in WB (by +0.2 degrees C, P less than 0.01) but not with control or WA. Abdominal ST rose only with WB (by +0.66 degrees C above baseline, P less than 0.01). FBF increased above baseline values with both WA (by +10 ml.l forearm-1.min-1) and WB (by +12 ml.l forearm-1.min-1), but neither was significantly greater than the control. SBF increased above baseline only with WB (by +202 mV, P less than 0.01), and this was significantly greater than control SBF. With an occluded hand circulation, deep venous oxygen content rose above baseline values with WB only (+6.0%, P less than 0.01) but was not greater than control with either method of hand heating. We conclude that using a warm-air box has less effect than a heated blanket on the measured variables.


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