Acute viral hepatitis E presenting with haemolytic anaemia and acute renal failure in a patient with glucose-6-phosphate dehydrogenase deficiency

2014 ◽  
Vol 45 (4) ◽  
pp. 245-246 ◽  
Author(s):  
Laxmikant Ramkumarsingh Tomar ◽  
Amitesh Aggarwal ◽  
Piyush Jain ◽  
Surender Rajpal ◽  
Mukul P Agarwal
1995 ◽  
Vol 15 (3) ◽  
pp. 255-257 ◽  
Author(s):  
Soud A. Al-Rasheed ◽  
Mohamed M. Al-Mugeiren ◽  
Abdullah A. Al-Salloum ◽  
Ibrahim M. Al-Fawaz ◽  
Mohammed O. Al-Sohaibani

2003 ◽  
Vol 14 (4) ◽  
pp. 230-231 ◽  
Author(s):  
Amitabh Monga ◽  
Ravinder PS Makkar ◽  
Anju Arora ◽  
Surabhi Mukhopadhyay ◽  
Ajay K Gupta

Hepatitis E virus is one of the leading causes of acute viral hepatitis in India but usually manifests as a mild self-limiting illness. Viral hepatitis in the presence of glucose-6-phosphate dehydrogenase (G6PD) deficiency may be associated with complications such as severe anemia, hemolysis, renal failure, hepatic encephalopathy and even death. The incidence of G6PD deficiency in the general population of northern India is reported to be between 2.2% and 14%. Despite both hepatitis E infection and G6PD deficiency being common, their impact on patient illness has only recently been reported. The present study reports a case of severe hemolysis in a patient with G6PD deficiency and hepatitis E infection.


2019 ◽  
Vol 69 (8) ◽  
pp. 1440-1442 ◽  
Author(s):  
Jose Diego Brito-Sousa ◽  
Thalie C Santos ◽  
Sara Avalos ◽  
Gustavo Fontecha ◽  
Gisely C Melo ◽  
...  

Abstract Despite glucose-6-phosphate dehydrogenase (G6PD) deficiency prevalence of 5% in the Amazon, primaquine is administered without G6PD screening. This is an important cause of hospitalization among Plasmodium vivax–infected individuals, leading to life-threatening anemia and acute renal failure across endemic areas. In Manaus, the frequency of primaquine-induced hemolysis was 85.2 cases per 100 000 primaquine users.


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