Physiologically-Based Pharmacokinetic Modeling and Simulation to Assess Potential Cytochrome P450 3A4 and Transporter-Mediated Drug−drug Interactions with Prucalopride as Victim

Cytochrome P450 3A4 ◽

Physiologically Based ◽

Evaluation of Cytochrome P450 3A4-Mediated Drug–Drug Interaction Potential for Cobimetinib Using Physiologically Based Pharmacokinetic Modeling and Simulation

Clinical Pharmacokinetics ◽

10.1007/s40262-016-0412-5 ◽

2016 ◽

Vol 55 (11) ◽

pp. 1435-1445 ◽

Cited By ~ 16

Author(s):

Nageshwar R. Budha ◽

Tao Ji ◽

Luna Musib ◽

Steve Eppler ◽

Mark Dresser ◽

...

Keyword(s):

Cytochrome P450 ◽

Drug Interaction ◽

Modeling And Simulation ◽

Interaction Potential ◽

Cytochrome P450 3A4 ◽

Physiologically Based ◽

Drug Drug Interaction

Physiologically based pharmacokinetic modeling and simulation to predict drug–drug interactions of ivosidenib with CYP3A perpetrators in patients with acute myeloid leukemia

Cancer Chemotherapy and Pharmacology ◽

10.1007/s00280-020-04148-3 ◽

2020 ◽

Vol 86 (5) ◽

pp. 619-632

Author(s):

Chandra Prakash ◽

Bin Fan ◽

Alice Ke ◽

Kha Le ◽

Hua Yang

Keyword(s):

Acute Myeloid Leukemia ◽

Drug Interactions ◽

Modeling And Simulation ◽

Myeloid Leukemia ◽

Physiologically Based ◽

Acute Myeloid ◽

Meta-Analysis of Nanoparticle Delivery to Tumors Using a Physiologically Based Pharmacokinetic Modeling and Simulation Approach

ACS Nano ◽

10.1021/acsnano.9b08142 ◽

2020 ◽

Vol 14 (3) ◽

pp. 3075-3095 ◽

Cited By ~ 16

Author(s):

Yi-Hsien Cheng ◽

Chunla He ◽

Jim E. Riviere ◽

Nancy A. Monteiro-Riviere ◽

Zhoumeng Lin

Keyword(s):

Modeling And Simulation ◽

Meta Analysis ◽

Simulation Approach ◽

Nanoparticle Delivery ◽

Physiologically Based ◽

Evaluation of Exposure Change of Nonrenally Eliminated Drugs in Patients With Chronic Kidney Disease Using Physiologically Based Pharmacokinetic Modeling and Simulation

The Journal of Clinical Pharmacology ◽

10.1177/0091270011415528 ◽

2012 ◽

Vol 52 (S1) ◽

Cited By ~ 69

Author(s):

Ping Zhao ◽

Manuela de L. T. Vieira ◽

Joseph A. Grillo ◽

Pengfei Song ◽

Ta‐Chen Wu ◽

...

Keyword(s):

Chronic Kidney Disease ◽

Kidney Disease ◽

Modeling And Simulation ◽

Physiologically Based ◽

Physiologically Based Pharmacokinetic Modeling and Simulation in Pediatric Drug Development

CPT Pharmacometrics & Systems Pharmacology ◽

10.1038/psp.2014.45 ◽

2014 ◽

Vol 3 (11) ◽

pp. 1-13 ◽

Cited By ~ 77

Author(s):

A R Maharaj ◽

A N Edginton

Keyword(s):

Drug Development ◽

Modeling And Simulation ◽

Pediatric Drug ◽

Pediatric Drug Development ◽

Physiologically Based ◽

Best Practice in the Use of Physiologically Based Pharmacokinetic Modeling and Simulation to Address Clinical Pharmacology Regulatory Questions

Clinical Pharmacology & Therapeutics ◽

10.1038/clpt.2012.68 ◽

2012 ◽

Vol 92 (1) ◽

pp. 17-20 ◽

Cited By ~ 127

Author(s):

P Zhao ◽

M Rowland ◽

S-M Huang

Keyword(s):

Clinical Pharmacology ◽

Modeling And Simulation ◽

Best Practice ◽

Physiologically Based ◽

Assessing drug interaction risk of the grapefruit juice component and dietary supplement 6′,7′‐dihydroxybergamottin via physiologically‐based pharmacokinetic modeling and simulation

The FASEB Journal ◽

10.1096/fasebj.27.1_supplement.1103.4 ◽

2013 ◽

Vol 27 (S1) ◽

Author(s):

Garrett Robert Ainslie ◽

Brandon T Gufford ◽

Christina S Won ◽

Kristina K Wolf ◽

Mary F Paine

Keyword(s):

Drug Interaction ◽

Modeling And Simulation ◽

Dietary Supplement ◽

Grapefruit Juice ◽

Physiologically Based ◽

Physiologically Based Pharmacokinetic Modeling and Simulation of Sunitinib in Pediatrics

The AAPS Journal ◽

10.1208/s12248-020-0423-x ◽

2020 ◽

Vol 22 (2) ◽

Author(s):

Yanke Yu ◽

Steven G. DuBois ◽

Cynthia Wetmore ◽

Reza Khosravan

Keyword(s):

Modeling And Simulation ◽

Physiologically Based ◽

Predicting Nonlinear Pharmacokinetics of Omeprazole Enantiomers and Racemic Drug Using Physiologically Based Pharmacokinetic Modeling and Simulation: Application to Predict Drug/Genetic Interactions

Pharmaceutical Research ◽

10.1007/s11095-013-1293-z ◽

2014 ◽

Vol 31 (8) ◽

pp. 1919-1929 ◽

Cited By ~ 15

Author(s):

Fang Wu ◽

Lu Gaohua ◽

Ping Zhao ◽

Masoud Jamei ◽

Shiew-Mei Huang ◽

...

Keyword(s):

Modeling And Simulation ◽

Genetic Interactions ◽

Nonlinear Pharmacokinetics ◽

Physiologically Based ◽

Investigating the Impact of Drug Crystallinity in Amorphous Tacrolimus Capsules on Pharmacokinetics and Bioequivalence Using Discriminatory In Vitro Dissolution Testing and Physiologically Based Pharmacokinetic Modeling and Simulation

Journal of Pharmaceutical Sciences ◽

10.1016/j.xphs.2017.12.024 ◽

2018 ◽

Vol 107 (5) ◽

pp. 1330-1341 ◽

Cited By ~ 22

Author(s):

Hitesh S. Purohit ◽

Niraj S. Trasi ◽

Dajun D. Sun ◽

Edwin C.Y. Chow ◽

Hong Wen ◽

...

Keyword(s):

Modeling And Simulation ◽

In Vitro Dissolution ◽

Dissolution Testing ◽

Physiologically Based ◽

The Impact ◽