Ultrasonographic Detection of Vascularity of Focal Breast Lesions: Microvascular Imaging Versus Conventional Color and Power Doppler Imaging

2021 ◽  
pp. 016173462110295
Author(s):  
Tommaso Vincenzo Bartolotta ◽  
Alessia Angela Maria Orlando ◽  
Maria Ilenia Schillaci ◽  
Luigi Spatafora ◽  
Mariangela Di Marco ◽  
...  

To compare microvascular flow imaging (MVFI) to conventional Color-Doppler (CDI) and Power-Doppler (PDI) imaging in the detection of vascularity of Focal Breast Lesions (FBLs). A total of 180 solid FBLs (size: 3.5–45.2 mm) detected in 180 women (age: 21–87 years) were evaluated by means of CDI, PDI, and MVFI. Two blinded reviewers categorized lesion vascularity in absent or present, and vascularity pattern as (a) internal; (b) vessels in rim; (c) combined. The presence of a “penetrating vessel” was assessed separately. Differences in vascularization patterns (chi2 test) and intra- and inter-observer agreement (Fleiss method) were calculated. ROC analysis was performed to assess performance of each technique in differentiating benign from malignant lesions. About 103/180 (57.2%) FBLs were benign and 77/180 (42.8%) were malignant. A statistically significant ( p < .001) increase in blood flow detection was observed for both readers with MVFI in comparison to either CDI or PDI. Benign FBLs showed mainly absence of vascularity ( p  = .02 and p  = .01 for each reader, respectively), rim pattern ( p < .001 for both readers) or combined pattern ( p = .01 and p = .04). Malignant lesions showed a statistically significant higher prevalence of internal flow pattern ( p < .001 for both readers). The prevalence of penetrating vessels was significantly higher with MVFI in comparison to either CDI or PDI ( p < .001 for both readers) and in the malignant FBLs ( p < .001). ROC analysis showed MVFI (AUC = 0.70, 95%CI = [0.64–0.77]) more accurate than CDI (AUC = 0.67, 95%CI = [0.60–0.74]) and PDI (AUC = 0.67, 95%CI = [0.60–0.74]) though not significantly ( p = .5436). Sensitivity/Specificity values for MVFI, PDI, and CDI were 76.6%/64.1%, 59.7%/73.8% and 58.4%/74.8%, respectively. Inter-reader agreement with MVFI was always very good ( k-score 0.85–0.96), whereas with CDI and PDI evaluation ranged from good to very good. No differences in intra-observer agreement were noted. MVFI showed a statistically significant increase in the detection of the vascularization of FBLs in comparison to Color and Power-Doppler.

1996 ◽  
Vol 84 (3) ◽  
pp. 459-461 ◽  
Author(s):  
Joanna M. Wardlaw ◽  
James C. Cannon

✓ “Color Doppler energy” (or “power Doppler”), a new color Doppler ultrasound technique that is independent of flow direction and very sensitive to movement, was assessed for its use in the identification of intracranial aneurysms in patients with recent subarachnoid hemorrhage immediately prior to using cerebral angiography. Features that identified aneurysms using this technique included the appearance of abnormal color where no normal artery was expected, abnormal bulging of an artery, and greater “expansibility” of the aneurysm in comparison to an adjacent normal vessel. In this exploratory study, 30 of 33 aneurysms were correctly identified in 35 patients with a good bone window. Color Doppler energy is considerably more sensitive to intracranial blood flow than conventional color Doppler imaging. Color Doppler energy is a useful research tool; if these preliminary results are verified in larger series, in addition to examination for vasospasm, the technique could be used for identification and follow up of aneurysms.


2000 ◽  
Vol 10 (1) ◽  
pp. 54-56 ◽  
Author(s):  
Satoshi Yasukochi ◽  
Gengi Satomi

AbstractWe successfully visualized the brachiocephalic arteries and aortic arch in a fetus seen at 19 weeks of gestation with a common arterial trunk and interrupted aortic arch by means of color power Doppler angiography, a new diagnostic development of color Doppler echocardiography. Power Doppler imaging is more sensitive to the state of low flow in fetal vessels, thus providing better visualization of fetal vascular structures from an early gestational stage.


1998 ◽  
Vol 16 (1) ◽  
pp. 41-45 ◽  
Author(s):  
Phebe Chen ◽  
Nabil Maklad ◽  
Michael Redwine

2002 ◽  
Vol 43 (5) ◽  
pp. 492-500 ◽  
Author(s):  
H. Reinikainen ◽  
E. Pääkkö ◽  
I. Suramo ◽  
M. Päivänsalo ◽  
J. Jauhiainen ◽  
...  

Purpose: To evaluate the dynamics of contrast enhancement in solid breast lesions at contrast-enhanced MR imaging and power Doppler ultrasonography (US) and to compare the methods to histology and to each other. Material and Methods: Forty breast lesions were prospectively examined with dynamic MR and power Doppler US. Time-signal intensity curves of enhancement were obtained for both methods. The shape of the curve was analyzed to be benign, indeterminate or malignant. The curves were also analyzed quantitatively by calculating the slope of the curve and the area under the curve (both methods), relative enhancement (MR), and time to peak (US). The lesions were divided into malignant lesions, fibroadenomas, and other benign lesions. The results were compared to histology. Results: In the subjective analysis of the MR curve in differentiating between benign and malignant lesions the accuracy was 90%. The MR curve also enabled differentiation between fibroadenomas and malignancies. The accuracy of the US curve was 38%. Quantitatively, statistically significant differences were found using all the MR variables, except between malignancies and fibroadenomas. Using the US variables, no significant difference was found between the groups. Conclusion: The dynamics of contrast-enhanced MR were reliable in the differential diagnosis of solid breast lesions, but contrast-enhanced power Doppler US was of limited value.


2017 ◽  
pp. 13-19 ◽  
Author(s):  
Z. A. Agaeva ◽  
T. S. Avhadov ◽  
L. V. Gorbov ◽  
E. N. Karanadze

Purpose: to improve the differential diagnosis of benign liver rumors and the liver metastasis of colorectal cancer with the ultrasound using contrast sonography.Materials and methods.There were evaluated 92 patients with liver neoplasms (44 (47.8%) women and 48 (52.2%) men) age 41 to 83, with a mean age of 62.8 ± 2.64. Ultrasound exam was carried out in three stages: I stage – liver ultrasound in B-mode, II stage – ultrasound in B-mode with addition of color Doppler imaging and power Doppler scanning, III stage – contrast liver sonography employing the contrast agent SonoVue (Bracco Imaging SpA, Milan, Italy). According to the results of the examination the patients were either surgically treated if there were indications, or the nature of the neoplasm was verified via the needle biopsy. Thus the patients formed two groups: I group (n = 35 (38.0%) – patients with benign liver neoplasms: cavernous hemangiomas – 17, hepatocellular adenomas – 3, focal modular hyperplasia of the liver – 5; II group (n = 57 (62.0%) – patients with metastasis of colorectal cancer.Results.With the use of the ultrasound in B-mode with addition of color Doppler imaging and power Doppler scanning in patients from group I (n = 35) with benign tumors of the liver – bilobar involvement in 2 cases, right lobe involvement in 28 cases, left lobe involvement in 5 cases. There were found both solitary (in 33 cases) and multiple (in 2 cases) neoplasms ranging from 2.5– 4.5 cm to conglomerates of 8–17 cm in diameter. In group II (n = 57), in patients with colorectal cancer metastasis who had an ultrasound examination in B-mode with addition of color Doppler imaging and power Doppler scanning, bilobar metastatic (91.2%) involvement of the liver prevailed over the monolobar, notably right lobe (84.21%) involvement was more frequent. Multiple metastasis were encountered more often (89.5%) then solitary. At the moment of metastatic liver disease discovery the size of the tumor nodules was over 5 cm in diameter in 33 (57.8%) patients. According to the results of contrast sonography in patients of group I (n = 35) with benign tumors of the liver, there was detected a prolonged enhancement of the neoplasm in the arterial, portal and delayed phases of enhancement. In patients of group II (n = 57) with metastasis of colorectal cancer to the liver, in the end of arterial phase there was noted a “washing out” of the contrast agent by 16th second – in 36 (63.1%) of the patients, by 23th se cond – in 17 (29.8%) and by the 26th second – in 4 (7.0%) of the patients. In portal and delayed phase of the enhancement all of the group II patients (100%) at the site of the metastasis there were located anechogenic round foci.Conclusions. 1. Complex 3-stage ultrasound examination (B-mode, color Doppler imaging and power Doppler scanning, contrast sonography) of the liver neoplasms allows to get a more detailed information and differentiate benign and metastatic disease of the liver; 2. During contrast sonography the benign liver tumors “keep” the contrast gent during the arterial, portal and delayed enhancement phases, but with metastasis in liver the contrast agent gets “washed out” already in the arterial phase of enhancement.


1998 ◽  
Vol 8 (2) ◽  
pp. 71-74 ◽  
Author(s):  
Stefan Ries ◽  
Wolfgang Steinke ◽  
Gerald Devuyst ◽  
Nikos Artemis ◽  
Attila Valikovics ◽  
...  

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