Longitudinal Change of Varicella-Zoster Virus-Specific Cell-Mediated Immunity in Hunt Syndrome and Bell’s Palsy

2014 ◽  
Vol 151 (1_suppl) ◽  
pp. P215-P215
Author(s):  
Takahiro Ichihara ◽  
Shin-Ichi Haginomori ◽  
Atsuko Mori ◽  
Atsuko Kanazawa ◽  
Akira Nishikado ◽  
...  
2013 ◽  
Vol 149 (2_suppl) ◽  
pp. P239-P239
Author(s):  
Takahiro Ichihara ◽  
Shin-Ichi Haginomori ◽  
Atsuko Mori ◽  
Atsuko Kanazawa ◽  
Ryo Kawata

2015 ◽  
Vol 126 (1) ◽  
pp. E35-E39 ◽  
Author(s):  
Shin-Ichi Haginomori ◽  
Takahiro Ichihara ◽  
Atsuko Mori ◽  
Atsuko Kanazawa ◽  
Ryo Kawata ◽  
...  

2000 ◽  
Vol 38 (7) ◽  
pp. 2753-2755 ◽  
Author(s):  
A. Pitkäranta ◽  
H. Piiparinen ◽  
L. Mannonen ◽  
M. Vesaluoma ◽  
A. Vaheri

Human herpesvirus 6 DNA was detected by PCR in the tear fluid of 7 (35%) of 20 patients with Bell's palsy and of 1 (5%) of 20 healthy controls. Varicella-zoster virus was detected by PCR in the tear fluid of 2 of 20 Bell's palsy patients but in none of the tear fluids from 20 healthy controls. These findings suggest an association between human herpesviruses and Bell's palsy.


2015 ◽  
Vol 79 (3) ◽  
pp. 328-331 ◽  
Author(s):  
Mosaad Abdel-Aziz ◽  
Noha A. Azab ◽  
Badwy Khalifa ◽  
Mohammed Rashed ◽  
Nader Naguib

2008 ◽  
Vol 198 (9) ◽  
pp. 1327-1333 ◽  
Author(s):  
Kay Sadaoka ◽  
Shigefumi Okamoto ◽  
Yasuyuki Gomi ◽  
Takeshi Tanimoto ◽  
Toyokazu Ishikawa ◽  
...  

F1000Research ◽  
2015 ◽  
Vol 4 ◽  
pp. 1356 ◽  
Author(s):  
Don Gilden ◽  
Maria Nagel ◽  
Randall Cohrs ◽  
Ravi Mahalingam ◽  
Nicholas Baird

Varicella zoster virus (VZV) is a ubiquitous, exclusively human alphaherpesvirus. Primary infection usually results in varicella (chickenpox), after which VZV becomes latent in ganglionic neurons along the entire neuraxis. As VZV-specific cell-mediated immunity declines in elderly and immunocompromised individuals, VZV reactivates and causes herpes zoster (shingles), frequently complicated by postherpetic neuralgia. VZV reactivation also produces multiple serious neurological and ocular diseases, such as cranial nerve palsies, meningoencephalitis, myelopathy, and VZV vasculopathy, including giant cell arteritis, with or without associated rash. Herein, we review the clinical, laboratory, imaging, and pathological features of neurological complications of VZV reactivation as well as diagnostic tests to verify VZV infection of the nervous system. Updates on the physical state of VZV DNA and viral gene expression in latently infected ganglia, neuronal, and primate models to study varicella pathogenesis and immunity are presented along with innovations in the immunization of elderly individuals to prevent VZV reactivation.


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