Pregnancy with St. Jude Medical Mitral Valve Prosthesis

2000 ◽  
Vol 8 (2) ◽  
pp. 127-129
Author(s):  
Birol Yamak ◽  
Mustafa Emir ◽  
Tulga A Ulus ◽  
Ayşen Aksöyek ◽  
Zafer Işcan ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Heart Valves ◽  
Oral Anticoagulant Therapy ◽  
Premature Delivery ◽  
Valve Prosthesis ◽  
Childbearing Age ◽  
Jude Medical ◽  
Mitral Valve Prosthesis ◽  
Maternal Morbidity And Mortality ◽  
Valve Thrombosis

From 1986 to 1995, 513 young women of childbearing age (11 to 45 years) underwent mitral valve replacement with a bileaflet St. Jude Medical prosthesis. Twenty-one patients became pregnant within 3 years postoperatively. The mean age of these patients at the onset of pregnancy was 27 ± 8 years (range, 16 to 43 years). Follow-up was complete for all pregnant patients. Of 11 who continued to take warfarin during pregnancy, one had a premature delivery, 2 had spontaneous abortions, and 8 had therapeutic abortions. Five patients who ceased oral anticoagulant therapy had normal deliveries but 4 underwent reoperation for valve thrombosis postnatally, with concurrent left hemiplegia in one case. The other 5 patients adhered to an anticoagulation protocol for pregnancy; there were 3 normal deliveries, 1 premature birth, and 1 abortion. There is a high risk of thromboembolism in patients with mechanical heart valves whose anticoagulants are interrupted during pregnancy. We believe that careful supervision can reduce maternal morbidity and mortality.

scholarly journals Stuck Mitral Valve with Thromboembolic Stroke Managed with Anticoagulation and Mechanical Thrombectomy

2020 ◽  
pp. 10-15
Author(s):  
Akshat Jain ◽  
Gurkirat Singh ◽  
Aniruddha Kaushik ◽  
Rahul Singla ◽  
Narendra Omprakash Bansal
Keyword(s):  
Mitral Valve ◽  
Heart Valves ◽  
Mechanical Valve ◽  
Developed Countries ◽  
Prosthetic Heart Valves ◽  
Valve Prosthesis ◽  
Short Term ◽  
Adequate Knowledge ◽  
Mitral Valve Prosthesis ◽  
Valve Thrombosis

Heart valve replacements are commonly performed these days in India with mitral valve replacement being most common of all. Thromboemboli are a major source of morbidity in patients with prosthetic heart valves. The incidence of clinically recognizable events ranges from 0.6% to 2.3% per patient-year. Mechanical valve thrombosis is another common complication, incidence of which is estimated at 0.3% to 1.3% per patient-year in developed countries, but as high as 6% per patient-year in developing countries. Management of either complication in these patients requires adequate knowledge and clinical experience. We here describe a rare case of a patient who came to us with both complication of stuck mitral valve prosthesis and embolic stroke simultaneously. We here discuss the approach, monitoring and management of these patients, the clinical difficulties we faced in our case, immediate and short term prognosis of our patient.

scholarly journals Thrombosis of mechanical mitral valve prosthesis during pregnancy: An ongoing “saga” in need of comprehensive solutions

2020 ◽  
Vol 2020 (3) ◽  
Author(s):  
Ahmed Mahgoub ◽  
Susy Kotit ◽  
Karim Bakry ◽  
Ahmed Magdy ◽  
Hatem Hosny ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Emergency Treatment ◽  
Maternal Morbidity ◽  
Mechanical Valve ◽  
Valve Prosthesis ◽  
Middle Income ◽  
Middle Income Countries ◽  
Mitral Valve Prosthesis ◽  
Maternal Morbidity And Mortality ◽  
Feasible Solutions

Emergency treatment for thrombosed mechanical valve prothesis during pregnancy is not uncommon in low- and middle-income countries. The presence of a mechanical valve continues to be an important cause of maternal morbidity and mortality. There is a pressing need for increasing awareness and feasible solutions for this huge problem. We here describe four patients who needed emergency treatment for thrombosis of mechanical valve prothesis during pregnancy and review the evolving comprehensive strategies for dealing with this issue.

Effect of Oral Anticoagulant during Pregnancy with Prosthetic Heart Valve

2002 ◽  
Vol 10 (4) ◽  
pp. 306-309 ◽  
Author(s):  
Ashok K Srivastava ◽  
Ashok K Gupta ◽  
Arvind V Singh ◽  
Tanveer Husain
Keyword(s):  
Heart Valve ◽  
Oral Anticoagulant ◽  
Oral Anticoagulants ◽  
Prosthetic Heart Valve ◽  
Premature Delivery ◽  
Valve Prosthesis ◽  
Childbearing Age ◽  
Skeletal Deformity ◽  
Mechanical Prosthesis ◽  
Valve Thrombosis

This retrospective study aimed to evaluate the risks and outcome of oral anticoagulant use during pregnancy in women with prosthetic heart valves. Between December 1989 and November 1998, 192 females of childbearing age underwent heart valve replacement with a mechanical prosthesis. There were 37 pregnancies in 30 patients during follow-up. Pregnancy was terminated on medical grounds in 5 cases, there were 2 (6%) spontaneous abortions, and 1 (3%) premature birth of a normal baby who died 24 hours later due to asphyxia. The other 29 pregnancies (91%) went to full term and the mothers continued taking oral anticoagulants until a week before the expected date of delivery, then switched to heparin. There was no thromboembolism, valve thrombosis, or maternal mortality. Three babies (10%) had a skeletal deformity: nasal hypoplasia in all 3, with cleft pinna in 1. Continuation of oral anticoagulants during pregnancy provided adequate protection against thromboembolism and valve thrombosis, but the risks of fetal abnormalities and premature delivery should be explained to women of childbearing age with a mechanical valve prosthesis.

Transesophageal color Doppler echocardiography of the normal St. Jude medical mitral valve prosthesis

1991 ◽  
Vol 122 (2) ◽  
pp. 489-494 ◽  
Author(s):  
Helmut W. Lange ◽  
Jeanne D. Olson ◽  
Wes R. Pedersen ◽  
Maureen A. Kane ◽  
James A. Daniel ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Doppler Echocardiography ◽  
Color Doppler ◽  
Valve Prosthesis ◽  
Color Doppler Echocardiography ◽  
Jude Medical ◽  
Mitral Valve Prosthesis

A mitral valve prosthesis and a study of thrombosis on heart valves in dogs

1962 ◽  
Vol 2 (3) ◽  
pp. 168-175 ◽  
Author(s):  
Wolfgang Seidel ◽  
Tetsuzo Akutsu ◽  
Velimir Mirkovitch ◽  
Willem J. Kolff
Keyword(s):  
Mitral Valve ◽  
Heart Valves ◽  
Valve Prosthesis ◽  
Mitral Valve Prosthesis

scholarly journals Periprosthetic leak mimicking entrapment of leaflet in a St. Jude Medical mitral valve prosthesis: Case report

1982 ◽  
Vol 83 (3) ◽  
pp. 471-472 ◽  
Author(s):  
Fernando R. Gutierrez ◽  
Alan J. Tiefenbrunn ◽  
Robert C. McKnighl ◽  
Richard E. Clark
Keyword(s):  
Case Report ◽  
Mitral Valve ◽  
Valve Prosthesis ◽  
Jude Medical ◽  
Mitral Valve Prosthesis ◽  
Periprosthetic Leak

scholarly journals Successful Use of Two Thrombolytic Drugs in Prosthetic Mitral and Aortic Valve Thrombosis

2020 ◽  
Author(s):  
Shayesteh Gheibi ◽  
Aliasghar Farsavian ◽  
Maryam Nabati ◽  
Gohar Eslami
Keyword(s):  
Mitral Valve ◽  
Aortic Valve ◽  
Anticoagulation Therapy ◽  
Mechanical Valve ◽  
Valve Prosthesis ◽  
Mechanical Prosthesis ◽  
First Line Therapy ◽  
Mitral Valve Prosthesis ◽  
Valve Thrombosis ◽  
Mobile Mass

Introduction: Prosthetic valve thrombosis is a rare and severe complication of valve replacement, most often encountered with a mechanical prosthesis. The significant morbidity and mortality associated with this condition warrant rapid diagnostic evaluation. Although surgery is the first-line therapy in symptomatic obstructive mechanical valve thrombosis, thrombolytic therapy has been used as an alternative. Case Description: In this case report, we describe a 46-year-old man with a history of the mitral valve and aortic valve replacement 2 years ago. In echocardiography, we detected a mobile mass on the atrial side of the mitral valve prosthesis and a fixed one on the leaflet of the mechanical aortic valve with a high gradient. To save his life, we used double thrombolytic therapy considering the patient’s hemodynamic situation and the risk of bleeding. Although a routine dose of reteplase and streptokinase was considered, we administered these two thrombolytic drugs together within 72 hours. Conclucsion: Ultimately we succeeded with this method without any significant or life-threatening adverse effects, and the patient was discharged after an optimal anticoagulation therapy.

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