Assessment of the interaction between a partial agonist and a full agonist of benzodiazepine receptors, based on psychomotor performance and memory, in healthy volunteers

1995 ◽  
Vol 9 (2) ◽  
pp. 91-101 ◽  
Author(s):  
A. Patat ◽  
M.C. Perault ◽  
B. Vandel ◽  
Ph. Danjou ◽  
S. Brohier ◽  
...  
Keyword(s):  
Healthy Volunteers ◽  
Psychomotor Performance ◽  
Partial Agonist ◽  
Benzodiazepine Receptors ◽  
Full Agonist

Lack of interaction between amisulpride and lorazepam on psychomotor performance and memory in healthy volunteers

1998 ◽  
Vol 13 (7) ◽  
pp. 493-500 ◽  
Author(s):  
M. C. Perault ◽  
L. Bergougnan ◽  
A. Paillat ◽  
I. Zieleniuk ◽  
P. Rosenzweig ◽  
...  
Keyword(s):  
Healthy Volunteers ◽  
Psychomotor Performance

RXR Partial Agonist Produced by Side Chain Repositioning of Alkoxy RXR Full Agonist Retains Antitype 2 Diabetes Activity without the Adverse Effects

2014 ◽  
Vol 58 (2) ◽  
pp. 912-926 ◽  
Author(s):  
Kohei Kawata ◽  
Ken-ichi Morishita ◽  
Mariko Nakayama ◽  
Shoya Yamada ◽  
Toshiki Kobayashi ◽  
...  
Keyword(s):  
Adverse Effects ◽  
Partial Agonist ◽  
Side Chain ◽  
Full Agonist

Effects of single dose of gamma-hydroxybutyric acid and lorazepam on psychomotor performance and subjective feelings in healthy volunteers

1999 ◽  
Vol 54 (11) ◽  
pp. 821-827 ◽  
Author(s):  
S. D. Ferrara ◽  
R. Giorgetti ◽  
S. Zancaner ◽  
R. Orlando ◽  
A. Tagliabracci ◽  
...  
Keyword(s):  
Single Dose ◽  
Healthy Volunteers ◽  
Psychomotor Performance ◽  
Hydroxybutyric Acid

scholarly journals The post-lunch effect of regular and decaffeinated coffee on psychomotor performance: a randomized double-blind cross-over study

2021 ◽  
Vol 10 (8) ◽  
pp. 954
Author(s):  
Suganthi S. Ramachandran ◽  
Vijay L. Kumar ◽  
S. N. Dwivedi ◽  
Vishwajeet Singh ◽  
Pooja Gupta
Keyword(s):  
Healthy Volunteers ◽  
Psychomotor Performance ◽  
Subjective Ratings ◽  
Double Blind ◽  
Flicker Fusion Frequency ◽  
Female Ratio ◽  
Cardiovascular Parameters ◽  
Significant Difference ◽  
Decaffeinated Coffee ◽  
The Mean

Background: This study aimed to compare the effect of regular coffee and decaffeinated coffee on psychomotor performance in healthy volunteers during post-lunch period.Methods: In this randomized double-blind cross-over study, adult healthy volunteers were given hot coffee (3 g each of regular or decaffeinated coffee) during post-lunch period. Psychomotor functions (critical flicker-fusion frequency (CFF), choice reaction time (CRT) and error count in hand-steadiness test (HST)), blood pressure and heart rate were measured pre-lunch, pre-coffee (1-hour post-lunch) and 1-hour post-coffee consumption. Subjective ratings of sleepiness and mood were also assessed during post-lunch sessions.Results: The mean age of the participants (n=16) was 27.4±2.7 years with a male: female ratio of 7:9. There was no significant deterioration in psychomotor performance post-lunch when compared to pre-lunch on both the days. The mean CFF, CRT, errors committed in HST and cardiovascular parameters did not differ significantly between regular coffee and decaffeinated groups during post-lunch sessions. There was no significant difference in values of cardiovascular parameters as well as subjective ratings of sleep and mood between two groups.Conclusions: In healthy adult individuals’ consumption of both regular coffee and decaffeinated coffee during the post-lunch period did not affect psychomotor performance.

Abecarnil is a Full Agonist at Some, and a Partial Agonist at Other Recombinant GABAA Receptor Subtypes

1993 ◽  
pp. 50-61 ◽  
Author(s):  
I. Pribilla ◽  
R. Neuhaus ◽  
R. Huba ◽  
M. Hillmann ◽  
J. D. Turner ◽  
...  
Keyword(s):  
Gabaa Receptor ◽  
Partial Agonist ◽  
Receptor Subtypes ◽  
Full Agonist ◽  
Gabaa Receptor Subtypes

The effects of remoxipride and chlorpromazine on eye movements and psychomotor performance in healthy volunteers

1995 ◽  
Vol 9 (2) ◽  
pp. 143-149 ◽  
Author(s):  
D.J. King ◽  
P. Best ◽  
G. Lynch ◽  
M.F. Mannion ◽  
R.C. Montgomery ◽  
...  
Keyword(s):  
Eye Movements ◽  
Healthy Volunteers ◽  
Psychomotor Performance

Antagonist, Partial Agonist, and Full Agonist Imidazo[1,5-a]quinoxaline Amides and Carbamates Acting through the GABAA/Benzodiazepine Receptor

1994 ◽  
Vol 37 (6) ◽  
pp. 758-768 ◽  
Author(s):  
Ruth E. TenBrink ◽  
Wha B. Im ◽  
Vimala H. Sethy ◽  
Andrew H. Tang ◽  
Don B. Carter
Keyword(s):  
Partial Agonist ◽  
Benzodiazepine Receptor ◽  
Full Agonist
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