Iohexol and Metrizoate in Urography of Insulin Dependent Patients

1986 ◽  
Vol 27 (3) ◽  
pp. 265-267 ◽  
Author(s):  
J. Edgren ◽  
L. Laasonen ◽  
P.-H. Groop ◽  
L. Groop

A double blind urographic study with the ionic contrast medium metrizoate or the non-ionic medium iohexol was perfomed on 69 insulin dependent diabetic patients. Metrizoate caused 24 per cent and iohexol 11 per cent mild adverse reactions and metrizoate a significant decrease in creatinine clearance values. Thus iohexol turned out to be better tolerated by these diabetic patients than metrizoate. References

1989 ◽  
Vol 30 (5) ◽  
pp. 509-515 ◽  
Author(s):  
Å. Billström ◽  
S.-O. Hietala ◽  
F. Lithner ◽  
J. Merikanto ◽  
M. Wirell ◽  
...  

A double-blind urographic and angiographic study was done with the ionic contrast medium meglumine metrizoate and the non-ionic iohexol in 90 patients with diabetes mellitus. Twenty patients were insulin dependent, and 70 non-insulin dependent diabetics. Diabetic patients with decreased as well as normal renal function prior to the examination sustained a reversible and small increase in the plasma creatinine level postexamination. The small increase caused by meglumine metrizoate was significantly higher than the increase caused by iohexol. There was also a significantly higher increase in plasma creatinine among the patients with diabetic nephropathy compared with those without nephropathy.


1984 ◽  
Vol 12 (3) ◽  
pp. 184-187 ◽  
Author(s):  
N Ducrey ◽  
B Curchod

Twenty insulin-dependent diabetic patients with signs of background retinopathy were given Buflomedil 600 mg/day orally or placebo in a randomized double-blind trial for a 6-month period. A larger number of patients had their retinal condition deteriorating in the placebo group and this finding is an indication for pursuing investigations on a larger scale in this direction.


Diabetes ◽  
1985 ◽  
Vol 34 (11) ◽  
pp. 1127-1133 ◽  
Author(s):  
R. K. Mayfield ◽  
P. V. Halushka ◽  
H. J. Wohltmann ◽  
M. Lopes-Virella ◽  
J. K. Chambers ◽  
...  

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