scholarly journals Carotid artery color Doppler ultrasonography and plasma levels of lipoprotein-associated phospholipase A2 and cystatin C in arteriosclerotic cerebral infarction

2019 ◽  
Vol 47 (9) ◽  
pp. 4389-4396 ◽  
Author(s):  
Lei Huang ◽  
Shengguo Yao

Objective This study was performed to evaluate the clinical application value of carotid artery color Doppler ultrasonography and the plasma levels of lipoprotein-associated phospholipase A2 (Lp-PLA2) and cystatin C (Cys C) in the diagnosis and treatment of arteriosclerotic cerebral infarction. Methods Sixty patients with arteriosclerotic cerebral infarction and 60 matched healthy participants were included. The patients were divided into mild, moderate, and severe groups according to their National Institutes of Health Stroke Scale (NIHSS) scores. Carotid artery intima plaque formation and the intima–media thickness (IMT) were observed using carotid artery color Doppler ultrasonography. The correlation between IMT and the Lp-PLA2 or Cys C level was statistically analyzed. Results Patients with arteriosclerotic cerebral infarction had a higher detection rate of carotid plaques, especially unstable plaques, than healthy participants. The plasma levels of Lp-PLA2 and Cys C were elevated in patients with arteriosclerotic cerebral infarction and increased with the NIHSS scores. The plasma levels of Lp-PLA2 and Cys C in patients with arteriosclerotic cerebral infarction were correlated with IMT. Conclusion The combination of carotid artery color Doppler ultrasonography with the Lp-PLA2 and Cys C plasma levels is of great clinical value in the diagnosis and treatment of arteriosclerotic cerebral infarction.

2018 ◽  
Vol 11 (3) ◽  
pp. 386-396 ◽  
Author(s):  
Roland Richard Macharzina ◽  
Sascha Kocher ◽  
Steven R. Messé ◽  
Thomas Rutkowski ◽  
Fabian Hoffmann ◽  
...  

2014 ◽  
Vol 2 (2) ◽  
Author(s):  
Sepideh Sefidbakht ◽  
Mohsen Agah ◽  
Zahra Habibagahi ◽  
Elham Aflaki ◽  
Amin Abolhasani Foroughi ◽  
...  

2013 ◽  
Vol 3 (1) ◽  
pp. 41-47
Author(s):  
Samir Kamenjaković ◽  
Farid Ljuca ◽  
Haris Huseinagić ◽  
Šefika Umihanić ◽  
Nihad Mešanović

Introduction: The aim of this research was to compare specifi city and sensitivity of Color Doppler ultrasonographywith CT angiography.Methods: A total of one hundred patients suffering from carotid artery disease (n=200) were tested in this research in the period from June till October, 2011. Average age of the patients was 61.5 years, and most of the patients were in the age group ranging from 55 to 65 years. The level of carotid artery stenosis is measured according to Standards of the North America Symptomatic Carotid Endarterectomy Trail study,by method of Color Doppler ultrasonography and CT angiography.Results: Stenosis <50% registered by Doppler ultrasonography was found in 62% and by CT angiography in 64% patients. Stenosis from 70 to 79% registered by Doppler ultrasonography was found in 88% and by CT angiography in 82% patients. In patients with level of stenosis 70-79% there was a tendencyof registering the stenosis to be higher by Color Doppler ultrasonography, than by CT angiography. In the case of the occlusion, there was also the similar observation, with variation of 8% carotid arteries.Conclusion: Extracranial Doppler and color duplex ultrasound enable reliable detection of both stenosis and occlusion of carotid arteries and accordingly they occupy an important place in radiological algorithm. When it comes to CT angiography it can be concluded that it can provide accurate and exact information regarding the condition of blood vessels as good as Digital Subtractive Angiography can.


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