scholarly journals Cognitive behavioural therapy improves pregnancy outcomes of in vitro fertilization-embryo transfer treatment: a systematic review and meta-analysis

2021 ◽  
Vol 49 (11) ◽  
pp. 030006052110507
Author(s):  
Ya-qin Li ◽  
Yun Shi ◽  
Chen Xu ◽  
Hong Zhou
Keyword(s):  
Systematic Review ◽  
Pregnancy Outcomes ◽  
Meta Analysis ◽  
Behavioural Therapy ◽  
Psychological Interventions ◽  
Vitro Fertilization ◽  
Cognitive Behavioural ◽  
Professional Psychologists ◽  
Ivf Et

Objective The study aim was to examine the effects of cognitive behavioural therapy (CBT) on the pregnancy outcomes of women receiving in vitro fertilization-embryo transfer (IVF-ET) treatment. Methods A literature review was performed using the databases MEDLINE, the Cochrane Database, Embase, Chinese National Knowledge Infrastructure (CNKI) and WANFANG. Eligible studies were selected according to inclusion and exclusion criteria. Relevant data were extracted and the quality of studies assessed. Odds ratios with 95% confidence intervals were pooled to statistically analyse the difference between intervention and control groups. Results Ten studies were selected for the systematic review and meta-analysis. The findings showed that CBT and cognitive-related therapy significantly improved the pregnancy rate of women undergoing IVF-ET treatment. Subgroup analysis showed that patients who received CBT, rather than complex psychological interventions, and those who received interventions delivered by professional psychologists, were more likely to become pregnant during IVF-ET treatment. Conclusion CBT and cognitive-related interventions had significant effects on the pregnancy outcomes of women receiving IVF-ET treatment. CBT treatment (rather than complex psychological interventions) provided by professional psychologists is strongly recommended.

scholarly journals Transcutaneous Electrical Acupoint Stimulation for Pregnancy Outcomes in Women Undergoing In Vitro Fertilization: A Protocol of Systematic Review and Meta-Analysis

2021 ◽  
Author(s):  
Han Yang ◽  
Juan Li ◽  
Guixing Xu ◽  
Zihao Zou ◽  
Mingsheng Sun ◽  
...  
Keyword(s):  
Systematic Review ◽  
In Vitro Fertilization ◽  
Pregnancy Rate ◽  
Pregnancy Outcomes ◽  
Meta Analysis ◽  
Childbearing Age ◽  
Ongoing Pregnancy Rate ◽  
Vitro Fertilization ◽  
Acupoint Stimulation

Abstract Background Infertility is a common health problem affecting couples at childbearing age. The proposal of in vitro fertilization (IVF) solves the problem of infertility to a certain extent. However, the average IVF success rates are low. Some studies conclude that transcutaneous electrical acupoint stimulation (TEAS) could improve pregnancy outcomes in women undergoing IVF. In consideration of the lack of comprehensive synthesis and evaluation of existing evidence, conducting a systematic review and meta-analysis is planned to determine whether TEAS is effective and safe to improve the pregnancy outcomes for women undergoing IVF. Methods Eight online databases will be searched from inception to June 2021. In addition, four clinical trial registries will also be searched, relevant references will be screened, and experts will be consulted for possible eligible studies. Randomized controlled trials (RCTs) which included patients with infertility who underwent IVF and used TEAS as the main adjuvant treatment versus non-TEAS or sham TEAS control will be included. The clinical pregnancy rate will be considered as the primary outcome. Ongoing pregnancy rate, miscarriage rate, live birth rate, emotion-related indicators, adverse events related to interventions, and other relevant indicators will be regarded as secondary outcomes. The selection, data extraction, and risk of bias assessment will be conducted by two independent researchers using Endnote software V.9.1 and RevMan software V.5.3. Moreover, data synthesis will be conducted using RevMan software V.5.3 and R software V.3.6.1. Ethics and dissemination: Ethical approval is not necessary because the current study will not include the original information of the individuals. We plan to publish the results in a peer-reviewed journal or disseminated in relevant conferences. Systematic review registration: PROSPERO registration number: CRD42021238871

scholarly journals Psychological interventions for people with psychotic experiences: A systematic review and meta-analysis of controlled and uncontrolled effectiveness and economic studies

2020 ◽  
Vol 54 (7) ◽  
pp. 673-695
Author(s):  
Emma Soneson ◽  
Debra Russo ◽  
Jan Stochl ◽  
Margaret Heslin ◽  
Julieta Galante ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cognitive Behavioural Therapy ◽  
Psychotic Disorders ◽  
Meta Analysis ◽  
Behavioural Therapy ◽  
Economic Evaluations ◽  
Psychological Interventions ◽  
Psychotic Experiences ◽  
Treatment As Usual ◽  
Cognitive Behavioural

Objective: Many people with psychotic experiences do not develop psychotic disorders, yet those who seek help demonstrate high clinical complexity and poor outcomes. In this systematic review and meta-analysis, we evaluated the effectiveness and cost-effectiveness of psychological interventions for people with psychotic experiences. Method: We searched 13 databases for studies of psychological interventions for adults with psychotic experiences, but not psychotic disorders. Our outcomes were the proportion of participants remitting from psychotic experiences (primary); changes in positive and negative psychotic symptoms, depression, anxiety, functioning, distress, and quality of life; and economic outcomes (secondary). We analysed results using multilevel random-effects meta-analysis and narrative synthesis. Results: A total of 27 reports met inclusion criteria. In general, there was no strong evidence for the superiority of any one intervention. Five studies reported on our primary outcome, though only two reports provided randomised controlled trial evidence that psychological intervention (specifically, cognitive behavioural therapy) promoted remission from psychotic experiences. For secondary outcomes, we could only meta-analyse trials of cognitive behavioural therapy. We found that cognitive behavioural therapy was more effective than treatment as usual for reducing distress (pooled standardised mean difference: −0.24; 95% confidence interval = [−0.37, −0.10]), but no more effective than the control treatment for improving any other outcome. Individual reports indicated that cognitive behavioural therapy, mindfulness-based cognitive therapy, sleep cognitive behavioural therapy, systemic therapy, cognitive remediation therapy, and supportive treatments improved at least one clinical or functional outcome. Four reports included economic evaluations, which suggested cognitive behavioural therapy may be cost-effective compared with treatment as usual. Conclusion: Our meta-analytic findings were primarily null, with the exception that cognitive behavioural therapy may reduce the distress associated with psychotic experiences. Our analyses were limited by scarcity of studies, small samples and variable study quality. Several intervention frameworks showed preliminary evidence of positive outcomes; however, the paucity of consistent evidence for clinical and functional improvement highlights a need for further research into psychological treatments for psychotic experiences. PROSPERO protocol registration number: CRD42016033869

scholarly journals Psychological interventions for alcohol use disorders in people living with HIV/AIDS: a systematic review

2019 ◽  
Vol 8 (1) ◽  
Author(s):  
Munyaradzi Madhombiro ◽  
Alfred Musekiwa ◽  
James January ◽  
Alfred Chingono ◽  
Melanie Abas ◽  
...  
Keyword(s):  
Systematic Review ◽  
Alcohol Use ◽  
Motivational Interviewing ◽  
Meta Analysis ◽  
Behavioural Therapy ◽  
Psychological Interventions ◽  
People Living With Hiv ◽  
Inclusion Criteria ◽  
Cognitive Behavioural ◽  
Living With Hiv

Abstract Background Alcohol use disorders (AUDs) in people living with HIV/AIDS (PLWH) are a significant impediment to achieving virological control. HIV non-suppression in PLWH with AUDs is mainly attributable to sub-optimal antiretroviral therapy adherence. Sub-optimal adherence makes control of the epidemic elusive, considering that effective antiretroviral treatment and viral suppression are the two key pillars in reducing new infections. Psychological interventions have been proposed as effective treatments for the management of AUDs in PLWH. Evidence for their effectiveness has been inconsistent, with two reviews (2010 and 2013) concluding a lack of effectiveness. However, a 2017 review that examined multiple HIV prevention and treatment outcomes suggested that behavioural interventions were effective in reducing alcohol use. Since then, several studies have been published necessitating a re-examination of this evidence. This review provides an updated synthesis of the effectiveness of psychological interventions for AUDs in PLWH. Methods A search was conducted in the following databases: PubMed, Cochrane Central Register of Trials (CENTRAL), MEDLINE (Ovid), EMBASE, PsychInfo (Ovid) and Clinical trials.gov (clinicaltrials.gov) for eligible studies until August 2018 for psychotherapy and psychosocial interventions for PLWH with AUDs. Two reviewers independently screened titles, abstracts and full texts to select studies that met the inclusion criteria. Two reviewers independently performed data extraction with any differences resolved through discussion. Risk of bias was assessed by two independent reviewers using the Cochrane risk of bias tool, and the concordance between the first and second reviewers was 0.63 and between the first and third reviewers 0.71. Inclusion criteria were randomised controlled trials using psychological interventions in people aged 16 and above, with comparisons being usual care, enhanced usual care, other active treatments or waitlist controls. Results A total of 21 studies (6954 participants) were included in this review. Studies had diverse populations including men alone, men and women and men who had sex with men (MSM). Use of motivational interviewing alone or blended with cognitive behavioural therapy (CBT) and technology/computer-assisted platforms were common as individual-level interventions, while a few studies investigated group motivational interviewing or CBT. Alcohol use outcomes were all self-report and included assessment of the quantity and the frequency of alcohol use. Measured secondary outcomes included viral load, CD4 count or other self-reported outcomes. There was a lack of evidence for significant intervention effects in the included studies. Isolated effects of motivational interviewing, cognitive behavioural therapy and group therapy were noted. However for some of the studies that found significant effects, the effect sizes were small and not sustained over time. Owing to the variation in outcome measures employed across studies, no meta-analysis could be carried out. Conclusion This systematic review did not reveal large or sustained intervention effects of psychological interventions for either primary alcohol use or secondary HIV-related outcomes. Due to the methodological heterogeneity, we were unable to undertake a meta-analysis. Effectiveness trials of psychological interventions for AUDs in PLWH that include disaggregation of data by level of alcohol consumption, gender and age are needed. There is a need to standardise alcohol use outcome measures across studies and include objective biomarkers that provide a more accurate measure of alcohol consumption and are relatively free from social desirability bias. Systematic review registration PROSPERO CRD 42017063856.

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