End-Stage Acute Hepatic Failure as Clinical Presentation of Liver Metastases from Breast Cancer

1998 ◽  
Vol 84 (5) ◽  
pp. 616-617 ◽  
Author(s):  
Yago Nieto ◽  
José Luis Alonso ◽  
Francisco Ayala ◽  
Luis Ortega ◽  
Antonio Casado ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Liver Disease ◽  
Liver Metastases ◽  
Breast Neoplasm ◽  
Hepatic Failure ◽  
Unusual Case ◽  
Clinical Presentation ◽  
Acute Hepatic Failure ◽  
History Of ◽  
End Stage

A most unusual case of fatal acute hepatic failure as clinical presentation of liver metastases from breast cancer is described. The patient had a four-year history of indolent breast neoplasm and no previously known liver disease.

A Case of Multiple Chemical Sensitivities: Cognitive Therapy for Somatization Disorder and Metaworry

2003 ◽  
Vol 17 (3) ◽  
pp. 267-277 ◽  
Author(s):  
Scott Temple
Keyword(s):  
Cognitive Therapy ◽  
Unusual Case ◽  
Clinical Presentation ◽  
Somatization Disorder ◽  
Case Conceptualization ◽  
Marital Problems ◽  
Multiple Chemical Sensitivities ◽  
Common Clinical Presentation ◽  
History Of ◽  
Multiple Chemical

“Multiple chemical sensitivities” has become an increasingly common clinical presentation to physicians, though it is infrequently seen by psychotherapists. This case report describes a 61-year-old woman who presents with a long history of chemical sensitivities, that led to a somatization disorder with debilitating agoraphobia, depression, and marital problems. Features of a variety of anxiety disorders are present, as are metacognitions that required an unusual case conceptualization. A cognitive therapy case conceptualization and treatment are described, which address the highly idiosyncratic clinical presentation of this patient.

scholarly journals Acute Liver Failure with Diffuse Liver Metastasis from Breast Cancer, Not Detected by Computed Tomography: 2 Case Reports

2018 ◽  
Vol 11 (3) ◽  
pp. 699-704 ◽  
Author(s):  
Takatsugu Ogata ◽  
Yuichiro Kikawa ◽  
Misato Ogata ◽  
Hironaga Satake ◽  
Yukimasa Hatachi ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Computed Tomography ◽  
Liver Metastasis ◽  
Liver Failure ◽  
Acute Liver Failure ◽  
Hepatic Failure ◽  
Poor Prognosis ◽  
Alcoholic Hepatitis ◽  
Case Reports ◽  
History Of

Diffuse liver metastasis is a rare pattern of liver metastasis that is associated with hepatic failure and poor prognosis. We experienced 2 cases of acute liver failure due to diffuse metastasis that could not be detected using computed tomography. In case 1, it was difficult to differentiate diffuse metastasis from alcoholic hepatitis. In case 2, it was difficult to diagnose diffuse liver metastasis because the patient had no history of malignancy. When liver enzyme levels are elevated, it is necessary to consider liver metastasis as a potential cause, regardless of computed tomography findings.

Fulminant Liver Failure in a Patient Affected by Polycystic Liver Disease and Liver Metastases from Breast Carcinoma

2009 ◽  
Vol 95 (4) ◽  
pp. 557-561 ◽  
Author(s):  
Giovanni Maria Fadda ◽  
Davide Adriano Santeufemia ◽  
Paolo Cossu-Rocca ◽  
Gianfranco Bardino ◽  
Salvatore Costantino ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Liver Disease ◽  
Breast Carcinoma ◽  
Liver Failure ◽  
Liver Metastases ◽  
Fulminant Liver Failure ◽  
Polycystic Liver Disease ◽  
Benign Condition ◽  
Polycystic Liver ◽  
Cyst Growth

Background Polycystic liver disease (PLD) is a rare, congenital, benign condition characterized by the presence of multiple bile-duct-derived epithelial cysts in the liver parenchyma. The disease is usually asymptomatic, but cyst growth can result in complications such as ascites, esophageal varices, jaundice and hepatic failure. The exact mechanism leading to cyst growth is unclear, but estrogenic stimulation and paracrine action of vascular endothelial growth factor (VEGF) are thought to play a role in the growth of cyst epithelium. Case report We report a case of acute liver failure in a young woman with PLD and liver metastases from breast carcinoma. Results No data are available in the literature about metastatic liver involvement in PLD patients affected by breast cancer. The prognosis of patients with liver metastases is generally poor but fulminant liver failure is a very rare occurrence. Estrogen stimulation seems to be a risk factor for breast cancer and severe PLD. In the reported case, the presence of either the cysts or the metastatic lesions may have resulted in more extensive liver damage. Conclusions The adoption of drugs selected in relation to their hepatic toxicity together with careful monitoring of liver function is warranted in the management of breast cancer patients affected by PLD, in order to reduce the risk of liver failure.

scholarly journals Intramuscular Dirofilariasis Mimicking an Orbital Metastasis in a Patient with Breast Cancer

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Brett M. Henderson ◽  
Christopher H. Hunt ◽  
Laurence J. Eckel ◽  
Kara M. Schwartz ◽  
Felix E. Diehn ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Metastatic Disease ◽  
Unusual Case ◽  
Parasitic Infection ◽  
Rectus Muscle ◽  
Orbital Metastasis ◽  
Surgical Biopsy ◽  
Superior Rectus ◽  
History Of ◽  
Superior Rectus Muscle

We present the unusual case of a 74 year-old female with a history of breast cancer who presented with acute painless orbital swelling and vertical diplopia. MRI revealed a focal enhancing mass within the superior rectus muscle. As the concern for metastatic disease was high, surgical biopsy was performed and revealed an unusual mimicker of metastatic disease, the parasitic infection dirofilariasis.

Solitary metastatic breast carcinoma in a trigeminal nerve mimicking a trigeminal neurinoma

1996 ◽  
Vol 85 (4) ◽  
pp. 677-680 ◽  
Author(s):  
Ichiro Nakano ◽  
Koichi Iwasaki ◽  
Akinori Kondo
Keyword(s):  
Breast Cancer ◽  
Trigeminal Nerve ◽  
Unusual Case ◽  
Metastatic Breast ◽  
Metastatic Tumor ◽  
Content Type ◽  
Metastatic Breast Carcinoma ◽  
Trigeminal Neurinoma ◽  
History Of ◽  
Histopathological Studies

✓ An unusual case of a metastatic adenocarcinoma located entirely within the trigeminal nerve is reported. The patient, with a history of breast cancer, presented with a pure trigeminal mononeuropathy. The neurological and neuroradiological findings in this patient were quite similar to those of a patient with trigeminal neurinoma. Surgery revealed that the tumor was located within the trigeminal nerve and its appearance was similar to that of a neurinoma. However, histopathological studies proved the tumor to be an adenocarcinoma that was related to the breast cancer treated earlier. A solitary metastatic tumor arising solely in a trigeminal nerve is quite rare; this is the first report of such a case metastasized from breast cancer.

scholarly journals Mortality and its Determinants in Adult Patients with End-stage Liver Disease on Waiting List for Liver Transplantation: A Preliminary Report on Baseline Data

2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Kamran Bagheri Lankarani ◽  
Behnam Honarvar ◽  
Mohammad Reza Rouhezamin ◽  
Hadi Raeisi Shahraki ◽  
Vahid Seifi ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Weight Loss ◽  
Liver Disease ◽  
Gallbladder Wall ◽  
Meld Score ◽  
Organ Allocation ◽  
Ca 125 ◽  
End Stage Liver Disease ◽  
History Of ◽  
End Stage

Background: Prevention of death in patients on the waiting list for liver transplantation (LT) is a major concern to prioritize organ allocation. Since the model for the end-stage liver disease (MELD) and its modifications have many shortages, there is a need for further refinement of the allocation strategy. Objectives: The current study aimed at assessing the predictors of mortality in LT candidates in a more comprehensive manner with the possible implications to improve the care of such patients and assist in developing better strategies for organ allocation. Methods: In the current cohort study, 544 adult LT candidates with end-stage liver disease were followed up for a mean of 12 months in three-month intervals. Data analysis was performed in Nutritionist, SPSS, and R software, using Kaplan-Meier, Cox proportional hazard (HRC), and LASSO Cox regression hazard (HRL) tests. Results: The mean age of the patients was 46.7 ± 13.7 years; the majority were male (n = 336, 61.7%). At the end of the study, 414 (76.1%) subjects were still alive and 130 (23.9%) dead. The cumulative percentages of death were 33.1%, 57.7%, and 79.2% after 3, 6, and 12 months of waiting for a donor, respectively. Although there was a strong association between having hepatopulmonary syndrome (HPS) (HRC = 4.7, HRL = 1.8), a history of myocardial infarction (MI) (HRC = 3.3, HRL = 1.6), low-carbohydrate (CHO) diet (HRC = 2.7, HRL = 1.5), and mortality, it was weak for MELD score. Moreover, a serum level of CA 125, high polymorphonuclear (PMN) count, weight loss, a high level of alanine aminotransferase (ALT), positive hepatitis B virus (HBV) markers, high mean corpuscular volume (MCV) of red blood cells, ascites, and edema of gallbladder wall had association with mortality in LT patients. Conclusions: In addition to MELD score, HPS, a history of MI, low CHO intake, weight loss, ascites, PMN, CA 125, ALT, hepatitis B surface antigen, MCV, blood urea nitrogen, and gallbladder wall thickness are predictors of mortality in LT candidates and need to be considered in the LT allocation system.

scholarly journals Necrolytic erythema migrans in celiac disease

2022 ◽  
Vol 13 (e) ◽  
pp. e1-e1
Author(s):  
Dassouli Ryme ◽  
Hanane BayBay ◽  
Souad Choukri ◽  
Zakia Douhi ◽  
Sara Elloudi ◽  
...  
Keyword(s):  
Celiac Disease ◽  
Liver Disease ◽  
Clinical Picture ◽  
Rare Case ◽  
Clinical Presentation ◽  
Erythema Migrans ◽  
Lower Abdomen ◽  
Intestinal Malabsorption ◽  
Timely Manner ◽  
History Of

Erythema migrans necrolytica is a red, blistering rash that spreads over the skin. It particularly affects the skin around the mouth and distal extremities, but can also be found on the lower abdomen, buttocks, perineum and groin. It is strongly associated with glucagonoma, a glucagon-producing tumor of the pancreas, but is also seen in a number of other conditions, including liver disease and intestinal malabsorption such as celiac disease. We present a case of a patient with a history of poorly followed celiac disease presenting with a clinical picture of ENM. This rare case adds to our understanding of the clinical presentation of NME, as well as highlights the importance of acting in a timely manner to avoid the most redoubtful complications.

Acute hepatic failure precipitated in a patient with subclinical liver disease by vibrionic and clostridial septicemia

Pathology ◽  
1988 ◽  
Vol 20 (2) ◽  
pp. 188-190 ◽  
Author(s):  
Thomas P. Simon ◽  
Sarvesh Rajakulendran ◽  
Heung-To Yeung
Keyword(s):  
Liver Disease ◽  
Hepatic Failure ◽  
Acute Hepatic Failure
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