scholarly journals Induction of Anaesthesia with Sevoflurane, Preprogrammed Propofol Infusion or Combined Sevoflurane/Propofol for Laryngeal Mask Insertion: Cardiovascular, Movement and EEG Bispectral Index Responses

1998 ◽  
Vol 26 (4) ◽  
pp. 360-365 ◽  
Author(s):  
D. W. Blake ◽  
M. N. Hogg ◽  
C. H. Hackman ◽  
J. Pang ◽  
A. R. Bjorksten

Inhalation induction with sevoflurane was compared with propofol or sevoflurane/propofol in 60 unpremedicated adults. Target concentrations for the three groups (with 60% nitrous oxide) were 3% end-tidal sevoflurane, 12 mg/l propofol and 1.5% sevoflurane/6 mg/l propofol respectively, prior to insertion of a laryngeal mask airway (LMA) at 10 minutes. Induction of anaesthesia was satisfactory in each group, but movement response to LMA insertion was observed in 20 patients (least in the sevoflurane group). Cardiovascular responses were similar except for a lower heart rate in the sevoflurane group. EEG bispectral index suggested a greater depth of anaesthesia in the inhalation induction group. A bispectral index of 60 separated patients responding to LMA insertion from nonresponders (P=0.006), and had a sensitivity of 68% and specificity 70%. Movement response was not predicted by cardiovascular changes.

2021 ◽  
Author(s):  
Tamaki Iwade ◽  
Koichi Ohno

Abstract BackgroundAlthough endotracheal tube is preferred for airway management during laparoscopic percutaneous extraperitoneal closure for inguinal hernias, laryngeal mask airway may also be used. However, few studies have reported the usefulness of laryngeal mask airway during laparoscopic percutaneous extraperitoneal closure. Our study aims to report the advantages of laryngeal mask airway versus endotracheal tube during laparoscopic percutaneous extraperitoneal closure for inguinal hernia in pediatric day surgery.MethodsThe records of 56 patients (Group I, endotracheal tube; Group II, laryngeal mask airway) treated for inguinal hernia using laparoscopic percutaneous extraperitoneal closure between November 2018 and December 2019 were retrospectively reviewed. The duration of anesthesia; changes in hemodynamics (heart rate and systolic/diastolic blood pressure), end-tidal carbon dioxide, and bispectral index; and postoperative complications were analyzed.ResultsGroups I and II had 39 and 17 patients, respectively. The duration of anesthesia and surgery and changes in hemodynamics and bispectral index were similar between the two groups. Induction and recovery times were significantly shorter and changes in end-tidal carbon dioxide were more significant in Group II (p < 0.05). The incidence of sore throat and nausea was higher in Group I (p < 0.05).ConclusionsLaryngeal mask airway was equivalent to endotracheal tube in terms of performance during laparoscopic percutaneous extraperitoneal closure, although induction and recovery were achieved sooner in laryngeal mask airway, with a lower incidence of sore throat and nausea.Trial RegistrationNot applicable


1997 ◽  
Vol 25 (4) ◽  
pp. 413-416 ◽  
Author(s):  
T. K. Kwek ◽  
A. Ng

The aim of this study was to compare laryngeal mask insertion conditions following inhalational induction with either halothane or sevoflurane. Fifty-eight healthy children scheduled for dental extraction were randomly assigned to receive nitrous oxide 66% in oxygen and 3.0 MAC of either halothane or sevoflurane introduced in a stepwise fashion. The laryngeal masks were inserted when an adequate depth of anaesthesia was attained and the reactions and time to insertion noted. Inhalational induction was smooth in both halothane and sevoflurane groups. Induction time and time to laryngeal mask insertion were significantly faster with sevoflurane. The conditions for laryngeal mask insertion were generally good with 86.2% and 89.2% in the halothane and sevoflurane groups respectively having had no reactions to insertion. The complications to laryngeal mask insertion encountered were mild. The emergence time from the anaesthetic was found to be shorter for sevoflurane but the difference was not statistically significant.


2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Cristina Monteserín-Matesanz ◽  
Tatiana González ◽  
María José Anadón-Baselga ◽  
Matilde Zaballos

Abstract Background ProSeal (PLMA) and Supreme (SLMA) laryngeal mask airways are effective ventilator devices with distinctive designs that may require different anaesthetics for insertion. Sevoflurane induction provides acceptable conditions for laryngeal mask insertion, and remifentanil significantly decreases the minimum alveolar concentration of sevoflurane required for that insertion. The study aimed to evaluate the optimal end-tidal (ET) sevoflurane concentration for successful insertion of PLMA versus SLMA in patients receiving a remifentanil infusion without a neuromuscular blocking agent. Methods Altogether, 45 patients ASA (American Society Anaesthesiologists) physical status I–II, aged 18–60 years were scheduled for elective ambulatory surgery. Exclusion criteria were a difficult airway, recent respiratory infection, reactive airway, obstructive sleep apnoea syndrome, gastric aspiration’s risk factors, pregnancy, and lactation. Patients were randomly allocated to receive the SLMA or the PLMA. Sevoflurane induction with co-administration of remifentanil was performed at an effect-site concentration of 4 ng mL− 1. ET50 was calculated with a modified Dixon’s up-and-down method (starting at 2.5% in steps of 0.5%). Predetermined sevoflurane concentration was kept constant during the 10 min before LMA insertion. Patient’s response to LMA insertion was classified as “movement” or “no movement”. Sevoflurane ET50 was determined as the midpoint concentration of all the independent pairs that manifested crossover from “movement” to “no movement”. Results The ET50 sevoflurane concentration co-administered with remifentanil required for PLMA insertion was 1.20 ± 0.41% (95% confidence interval 0.76 to 1.63%). For SLMA insertion, it was 0.55 ± 0.38% (95% confidence interval 0.14 to 0.95%) (p = 0.019). Conclusions The end-tidal sevoflurane concentration with co-administered remifentanil required to allow insertion of the SLMA was 54% lower than that needed for inserting the PLMA. Trial registration Clinicaltrials.gov identifier: NCT03003377. Retrospectively registered. Date of registration: December 28, 2016.


2003 ◽  
Vol 99 (5) ◽  
pp. 1055-1058 ◽  
Author(s):  
Shinichi Kihara ◽  
Yuichi Yaguchi ◽  
Shinichi Inomata ◽  
Seiji Watanabe ◽  
Joseph R. Brimacombe ◽  
...  

Background Inhalational induction with sevoflurane and nitrous oxide is frequently used for Laryngeal Mask Airway (LMA; Laryngeal Mask Company, Henley-on-Thames, United Kingdom) insertion in children. The authors determined the influence of nitrous oxide on the minimum alveolar concentration (MAC) of sevoflurane for LMA insertion. Methods One hundred twenty unpremedicated children (age, 1-9 yr; American Society of Anesthesiologists physical status I) were randomly assigned to receive 1 of 15 end-tidal concentrations of nitrous oxide and sevoflurane for inhalational induction via a facemask: 0% nitrous oxide with 1.2, 1.4, 1.6, 1.8, or 2.0% sevoflurane; 33% nitrous oxide with 0.8, 1.0, 1.2, 1.4, or 1.6% sevoflurane; or 67% nitrous oxide with 0.4, 0.6, 0.8, 1.0, or 1.2% sevoflurane. The LMA was inserted after steady state end-tidal anesthetic concentrations had been maintained for 15 min. The response to insertion was recorded by three independent blinded observers. The interaction between nitrous oxide and sevoflurane was determined using logistic regression analysis. Results The MAC of sevoflurane for LMA insertion (95% confidence limit) was 1.57% (1.42-1.72%), and the concentration of sevoflurane required to prevent movement in 95% of children was 1.99% (1.81-2.57%). The addition of 33% and 67% nitrous oxide linearly decreased the MAC of sevoflurane for LMA insertion by 22% and 49%, respectively (P &lt; 0.001). The interaction coefficient between nitrous oxide and sevoflurane did not differ from zero (P = 0.7843), indicating that the relation was additive. Conclusions Nitrous oxide and sevoflurane suppress the responses to LMA insertion in a linear and additive fashion in children.


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