Deranged Pulmonary Function Tests in Allergic Rhinitis in North Indian Patients

Introduction: Significant associations between allergic rhinitis and bronchial asthma have been established and as a result of bronchial hyper-responsiveness, patients can have deranged pulmonary function tests. We aim to compare previous such studies with the result of our study done in India wherein we identify among allergic rhinitis patients who despite not having overt asthmatic symptoms, have pulmonary function derangements, quite possibly at a subclinical disease level. Materials and Methods: We studied 74 patients of allergic rhinitis and after meticulous clinical work up, they underwent blood tests including hemogram, absolute eosinophil count, and total serum IgE followed by pulmonary function tests. Results: Out of 74 patients 60 (81%) had intermittent allergic rhinitis whereas only 14 (19%) had persistent allergic rhinitis. Pulmonary function tests showed reversible obstruction, ie, >10% improvement in FEV1 with inhaled bronchodilators (as seen in asthma) in 18 (24.3%), mild obstruction in 14, and moderate obstruction in 4 cases. Conclusion: The study emphasizes the importance of pulmonary symptoms and the performance of pulmonary function tests in cases of allergic rhinitis patients to rule out latent asthma.

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Relationship between pulmonary function tests, sputum eosinophilia and total serum IgE levels among asthmatic patients in Duhok, Iraq

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20202239 ◽

2020 ◽

Vol 8 (6) ◽

pp. 2033

Author(s):

Hamdia Yousif Issa ◽

Ali A. Ramadhan ◽

Abdulazeez S. Safo ◽

Omar A. M. Al Habib

Keyword(s):

Pulmonary Function ◽

Severe Asthma ◽

Inflammatory Markers ◽

Pulmonary Function Tests ◽

Asthma Severity ◽

Total Serum ◽

Serum Ige ◽

Sputum Eosinophilia ◽

Asthmatic Patients ◽

Function Tests

Background: Bronchial asthma is a disease characterized by reversible airway obstruction, airway inflammation; and hyper-responsiveness. The prevalence of asthma is high, and both its prevalence and burden have increased over the last several decades. The study of inflammatory markers has implications for the appropriate management of this disease. Inflammatory markers has implications for the appropriate management of this disease. Objective of the study is to determine the correlation between asthma severity using pulmonary function tests with sputum eosinophilia and total serum IgE levels.Methods: This case-control study was conducted from March 2017 to September 2018 in the respiratory unit of Azadi general teaching hospital. It included 42 asthmatic patients and 18 healthy subjects. They underwent pulmonary function tests and measurement of total serum IgE levels. Induced sputum was done for asthmatic patients.Results: The age of asthmatic patients ranged from 16-70 years (mean 42±19 years). The asthmatic patient’s female: male ratio was 1.8. Mild asthma was the most common severity group (N=18, 43%) followed by moderate asthma (N=14, 33%) then severe asthma (N=10, 24%). Abnormal sputum eosinophilia (≥3%) was detected in 90% of severe asthma (N=9) compared to 36% in moderate asthma (N=5) and 5.6% in mild asthma (N=1). There was significant statistical association between asthma severity and sputum eosinophilia (p=0.00004). The association between asthma severity and total serum IgE levels was highly significant (p<0.0000) with levels of total serum IgE increasing as the severity of asthma increases.Conclusions: Severe asthma is the least common severity group in this study. Both abnormal sputum eosinophilia and total serum IgE levels are associated with the severity of asthma.

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A Comparative Study of Symptoms, Nasal Eosinophilia and Pulmonary Function Tests Before and After Short Term Treatment with Corticosteroid Nasal Spray in Patients with Allergic Rhinitis

Indian Journal of Otolaryngology and Head & Neck Surgery ◽

10.1007/s12070-020-02034-1 ◽

2020 ◽

Author(s):

Keshav Mangalore Pai ◽

Suresh Pillai ◽

Harshita Sabhahit Pai ◽

Shama Shetty

Keyword(s):

Allergic Rhinitis ◽

Comparative Study ◽

Pulmonary Function ◽

Nasal Spray ◽

Pulmonary Function Tests ◽

Term Treatment ◽

Short Term ◽

Short Term Treatment ◽

Function Tests ◽

Before And After

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Correlation of Height Parameter and Pulmonary Function Test with Grade of Allergic Rhinitis and Asthma in Children

International Journal of Innovative Research in Medical Science ◽

10.23958/ijirms/vol05-i08/937 ◽

2020 ◽

Vol 5 (08) ◽

pp. 349-352

Author(s):

Sadaf Choudhary ◽

Keya Rani Lahiri ◽

Fehmida Najmuddin

Keyword(s):

Allergic Rhinitis ◽

Pulmonary Function ◽

Pulmonary Function Test ◽

Pulmonary Function Tests ◽

Persistent Asthma ◽

P Value ◽

Function Tests ◽

Function Test

Introduction: Allergic Rhinitis and Asthma adversely affects height in children and it could be considered as an objective tool to assess severity, compliance and lung functions in children. We studied the correlation between height and pulmonary function tests with classification of allergic rhinitis and asthma. Aims & Objectives: 1) To study the height parameter with the grade of asthma and allergic rhinitis 2) To evaluate the pulmonary function test with the severity of asthma and allergic rhinitis 3) To correlate height and pulmonary function test with the classification of asthma and allergic rhinitis. Material and Methods: A prospective study including 30 patients in the age group of 5-12 years diagnosed with allergic rhinitis (AR) and bronchial asthma was conducted in a private tertiary care hospital in Navi Mumbai. History was entered in a pre-designed proforma and height was measured using a calibrated stadiometer along with pulmonary function tests recorded at the initial and two visits, 3 months apart. Results: Height increased significantly in patients without AR (p-value<0.01), with mild intermittent (p-value=0.02) and mild persistent AR (p-value<0.01) on subsequent visits. Patients with intermittent, mild persistent and moderate persistent asthma showed a statistically significant increase in height (p-value<0.01) with subsequent assessments. No significant increase in height was noted in patients with moderate persistent AR (p-value=0.14) and severe persistent asthma (p-value=0.16). At baseline, the height correlated significantly with FEV1 (p value<0.01), FVC (p value<0.01), Pre and Post-PEFR (p value<0.01, each). This trend continued at the first follow up. At the second follow-up, height correlated significantly with all parameters of pulmonary function tests (p value<0.01 for FEV1, FVC, FEV1/FVC ratio and PEFR). Conclusion: Height correlation with classification of AR and Asthma along with pulmonary function test has emerged as a simple, safe, cost-effective method in assessing control and monitoring the disease.

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